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PDB: 55 件

2BVT
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The structure of a modular endo-beta-1,4-mannanase from Cellulomonas fimi explains the product specificity of glycoside hydrolase family 26 mannanases.
分子名称: BETA-1,4-MANNANASE, CACODYLATE ION, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose
著者Le Nours, J, Anderson, L, Stoll, D, Stalbrand, H, Lo Leggio, L.
登録日2005-07-04
公開日2005-09-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Structure and Characterization of a Modular Endo-Beta-1,4-Mannanase from Cellulomonas Fimi
Biochemistry, 44, 2005
2BVY
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The structure and characterization of a modular endo-beta-1,4-mannanase from Cellulomonas fimi
分子名称: ACETATE ION, BETA-1,4-MANNANASE, CACODYLATE ION, ...
著者Le Nours, J, Anderson, L, Stoll, D, Stalbrand, H, Lo Leggio, L.
登録日2005-07-04
公開日2005-09-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Structure and Characterization of a Modular Endo-Beta-1,4-Mannanase from Cellulomonas Fimi
Biochemistry, 44, 2005
2J74
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Structure of Beta-1,4-Galactanase
分子名称: CALCIUM ION, YVFO, beta-D-galactopyranose-(1-4)-beta-D-galactopyranose, ...
著者Le Nours, J, De Maria, L, Welner, D, Jorgensen, C.T, Christensen, L.L.H, Larsen, S, Lo Leggio, L.
登録日2006-10-06
公開日2007-12-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Investigating the Binding of Beta-1,4-Galactan to Bacillus Licheniformis Beta-1,4-Galactanase by Crystallography and Computational Modeling.
Proteins, 75, 2009
2CCR
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Structure of Beta-1,4-Galactanase
分子名称: CALCIUM ION, TRIETHYLENE GLYCOL, YVFO, ...
著者Le Nours, J, De Maria, L, Welner, D, Jorgensen, C.T, Christensen, L.L.H, Larsen, S, Lo Leggio, L.
登録日2006-01-18
公開日2006-03-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Investigating the Binding of Beta-1,4-Galactan to Bacillus Licheniformis Beta-1,4-Galactanase by Crystallography and Computational Modeling.
Proteins, 75, 2009
1HJS
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Structure of two fungal beta-1,4-galactanases: searching for the basis for temperature and pH optimum.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BETA-1,4-GALACTANASE, ...
著者Le Nours, J, Ryttersgaard, C, Lo Leggio, L, Ostergaard, P.R, Borchert, T.V, Christensen, L.L.H, Larsen, S.
登録日2003-02-27
公開日2003-06-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structure of Two Fungal Beta-1,4-Galactanases: Searching for the Basis for Temperature and Ph Optimum
Protein Sci., 12, 2003
6MWR
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Recognition of MHC-like molecule
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Le Nours, J, Rossjohn, J.
登録日2018-10-30
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A class of gamma delta T cell receptors recognize the underside of the antigen-presenting molecule MR1.
Science, 366, 2019
4BWG
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Structural basis of subtilase cytotoxin SubAB assembly
分子名称: GLYCEROL, SUBA, SUBTILASE CYTOTOXIN, ...
著者Le Nours, J, Paton, A.W, Byres, E, Troy, S, Herdman, B.P, Johnson, M.D, Paton, J.C, Rossjohn, J, Beddoe, T.
登録日2013-07-02
公開日2013-08-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis of Subtilase Cytotoxin Subab Assembly.
J.Biol.Chem., 288, 2013
4WW1
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Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8 and Beta Chain-TRBV7-8
分子名称: TCR Alpha Chain-TRAV21-TRAJ8, TCR Beta Chain-TRBV7-8
著者Le Nours, J, Praveena, T, Pellicci, D.G, Lim, R.T, Besra, G, Howell, A.R, Godfrey, D.I, Rossjohn, J, Uldrich, A.P.
登録日2014-11-10
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Nat Commun, 7, 2016
4WW2
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Crystal structure of human TCR Alpha Chain-TRAV21-TRAJ8, Beta Chain-TRBV7-8, Antigen-presenting glycoprotein CD1d, and Beta-2-microglobulin
分子名称: (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ...
著者Le Nours, J, Praveena, T, Pellicci, D, Gherardin, N.A, Lim, R.T, Besra, G, Keshipeddy, S, Richardson, S.K, Howell, A.R, Gras, S, Godfrey, D.I, Rossjohn, J, Uldrich, A.P.
登録日2014-11-10
公開日2016-02-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Nat Commun, 7, 2016
4WWK
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Crystal structure of human TCR Alpha Chain-TRAV12-3, Beta Chain-TRBV6-5, Antigen-presenting molecule CD1d, and Beta-2-microglobulin
分子名称: (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ...
著者Le Nours, J, Praveena, T, Pellicci, D.G, Gherardin, N.A, Lim, R.T, Besra, G, Keshipeddy, A, Richardson, S.K, Howell, A.R, Gras, S, Godfrey, D.I, Rossjohn, J, Uldrich, A.P.
登録日2014-11-11
公開日2016-02-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.
Nat Commun, 7, 2016
3ZZM
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Crystal structure of Mycobacterium tuberculosis PurH with a novel bound nucleotide CFAIR, at 2.2 A resolution.
分子名称: 5-(FORMYLAMINO)-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, GLYCEROL, ...
著者Le Nours, J, Bulloch, E.M.M, Zhang, Z, Greenwood, D.R, Middleditch, M.J, Dickson, J.M.J, Baker, E.N.
登録日2011-09-02
公開日2011-09-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium Tuberculosis Reveal a Novel Bound Nucleotide.
J.Biol.Chem., 286, 2011
4A1O
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Crystal structure of Mycobacterium tuberculosis PurH complexed with AICAR and a novel nucleotide CFAIR, at 2.48 A resolution.
分子名称: 5-(FORMYLAMINO)-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, ...
著者Le Nours, J, Bulloch, E.M.M, Zhang, Z, Greenwood, D.R, Middleditch, M.J, Dickson, J.M.J, Baker, E.N.
登録日2011-09-17
公開日2011-09-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium Tuberculosis Reveal a Novel Bound Nucleotide.
J.Biol.Chem., 286, 2011
1HJU
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BU of 1hju by Molmil
Structure of two fungal beta-1,4-galactanases: searching for the basis for temperature and pH optimum.
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-1,4-GALACTANASE, ...
著者Le Nours, J, Ryttersgaard, C, Lo Leggio, L, Ostergaard, P.R, Borchert, T.V, Christensen, L.L.H, Larsen, S.
登録日2003-02-27
公開日2003-06-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of Two Fungal Beta-1,4-Galactanases: Searching for the Basis for Temperature and Ph Optimum
Protein Sci., 12, 2003
1HJQ
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Structure of two fungal beta-1,4-galactanases: searching for the basis for temperature and pH optimum.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-1,4-GALACTANASE
著者Le Nours, J, Ryttersgaard, C, Lo Leggio, L, Ostergaard, P.R, Borchert, T.V, Christensen, L.L.H, Larsen, S.
登録日2003-02-27
公開日2003-07-25
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of Two Fungal Beta-1,4-Galactanases: Searching for the Basis for Temperature and Ph Optimum
Protein Sci., 12, 2003
6BNL
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Crystal structure of TCR-MHC-like molecule
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Le Nours, J, Rossjohn, J.
登録日2017-11-16
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.
Cell Chem Biol, 25, 2018
6BNK
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Crystal structure of TCR-MHC-like molecule
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Le Nours, J, Rossjohn, J.
登録日2017-11-16
公開日2018-04-04
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.
Cell Chem Biol, 25, 2018
2GFT
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BU of 2gft by Molmil
Crystal structure of the E263A nucleophile mutant of Bacillus licheniformis endo-beta-1,4-galactanase in complex with galactotriose
分子名称: CALCIUM ION, Glycosyl Hydrolase Family 53, beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose
著者Welner, D, Le Nours, J, De Maria, L, Jorgensen, C.T, Christensen, L.L.H, Larsen, S, Lo Leggio, L.
登録日2006-03-23
公開日2006-06-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Oligosaccharide binding of Bacillus licheniformis endo-beta-1,4-galactanase
To be Published
8SGM
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Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR Beta-Chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ...
著者Chan Yew Poa, K.T.O, Le Nours, J, Rossjohn, J.
登録日2023-04-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.50000215 Å)
主引用文献Semi-invariant human type II Natural Killer T cells recognise CD1d independently of bound lipids.
To Be Published
8SGB
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Crystal Structure of CD1d-lipid complexed with Beta-2-Microglobulin, TCR Alpha-Chain and TCR Beta-Chain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
著者Chan Yew Poa, K.T.O, Le Nours, J, Rossjohn, J.
登録日2023-04-12
公開日2024-04-24
実験手法X-RAY DIFFRACTION (2.80001545 Å)
主引用文献Semi-invariant human type II Natural Killer T cells recognise CD1d independently of bound lipids.
To Be Published
5J1A
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Antigen presenting molecule
分子名称: 3-[(8Z,11Z)-pentadeca-8,11-dien-1-yl]benzene-1,2-diol, Beta-2-microglobulin, T-cell surface glycoprotein CD1a
著者Yongqing, T, Rossjohn, J, Le Nours, J, Marquez, E, Winau, F.
登録日2016-03-29
公開日2016-08-03
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献CD1a on Langerhans cells controls inflammatory skin disease.
Nat. Immunol., 17, 2016
7UFJ
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Structure of human MR1-ethylvanillin in complex with human MAIT A-F7 TCR
分子名称: 3-ethoxy-4-hydroxybenzaldehyde, ACETATE ION, Beta-2-microglobulin, ...
著者Wang, C.J, Rossjohn, J, Le Nours, J.
登録日2022-03-22
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Quantitative affinity measurement of small molecule ligand binding to Major Histocompatibility Complex class-I related protein 1 MR1.
J.Biol.Chem., 298, 2022
7M72
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MHC-like protein complex structure
分子名称: (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxy-15-methylhexadecan-2-yl]-3-hydroxyheptadecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Thirunavukkarasu, P, Le Nours, J, Rossjohn, J.
登録日2021-03-26
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Host immunomodulatory lipids created by symbionts from dietary amino acids.
Nature, 600, 2021
4GUP
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Structure of MHC-class I related molecule MR1
分子名称: 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde, Beta-2-microglobulin, CHLORIDE ION, ...
著者Patel, O, Le Nours, J, Rossjohn, J.
登録日2012-08-29
公開日2012-10-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献MR1 presents microbial vitamin B metabolites to MAIT cells
Nature, 491, 2012
2WZM
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Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form
分子名称: ALDO-KETO REDUCTASE, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
著者Scoble, J, McAlister, A.D, Fulton, Z, Troy, S, Byres, E, Vivian, J.P, Brammananth, R, Wilce, M.C.J, Le Nours, J, Zaker-Tabrizi, L, Coppel, R.L, Crellin, P.K, Rossjohn, J, Beddoe, T.
登録日2009-11-30
公開日2010-02-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase.
J.Mol.Biol., 398, 2010
6XNG
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MHC-like protein complex structure
分子名称: (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxyheptadecan-2-yl]-3-hydroxyheptadecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Thirunavukkarasu, P, Le Nours, J, Rossjohn, J.
登録日2020-07-02
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Host immunomodulatory lipids created by symbionts from dietary amino acids.
Nature, 600, 2021

 

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