2BT3
 
 | | AGAO in complex with Ruthenium-C4-wire at 1.73 angstroms | | Descriptor: | BIS[1H,1'H-2,2'-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1'~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM, COPPER (II) ION, GLYCEROL, ... | | Authors: | Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B. | | Deposit date: | 2005-05-26 | | Release date: | 2005-09-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Reversible Inhibition of Copper Amine Oxidase Activity by Channel-Blocking Ruthenium(II) and Rhenium(I) Molecular Wires.
Proc.Natl.Acad.Sci.USA, 102, 2005
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5VJQ
 | | Complex between HyHEL10 Fab fragment heavy chain mutant (I29F, S52T, Y53F) and Pekin duck egg lysozyme isoform I (DEL-I) | | Descriptor: | CHLORIDE ION, GLYCEROL, HyHEL10 heavy chain Fab fragment carrying three mutations; I29F, ... | | Authors: | Langley, D.B, Christ, D. | | Deposit date: | 2017-04-19 | | Release date: | 2018-04-11 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.
Science, 360, 2018
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1DUV
 | | CRYSTAL STRUCTURE OF E. COLI ORNITHINE TRANSCARBAMOYLASE COMPLEXED WITH NDELTA-L-ORNITHINE-DIAMINOPHOSPHINYL-N-SULPHONIC ACID (PSORN) | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, NDELTA-(N'-SULPHODIAMINOPHOSPHINYL)-L-ORNITHINE, ORNITHINE TRANSCARBAMOYLASE | | Authors: | Langley, D.B, Templeton, M.D, Fields, B.A, Mitchell, R.E, Collyer, C.A. | | Deposit date: | 2000-01-18 | | Release date: | 2000-07-04 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Mechanism of inactivation of ornithine transcarbamoylase by Ndelta -(N'-Sulfodiaminophosphinyl)-L-ornithine, a true transition state analogue? Crystal structure and implications for catalytic mechanism.
J.Biol.Chem., 275, 2000
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4X4X
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4X4Z
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2ZCG
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2ZP2
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7RTA
 | | Crystal structures of human PYY and NPY | | Descriptor: | 4A3B2-B Fab heavy chain, 4A3B2-B Fab light chain, Neuropeptide Y, ... | | Authors: | Langley, D.B, Christ, D. | | Deposit date: | 2021-08-12 | | Release date: | 2022-03-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY).
Neuropeptides, 92, 2022
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7RT9
 | | Crystal structures of human PYY and NPY | | Descriptor: | 4A3B2-A Fab heavy chain, 4A3B2-A Fab light chain, GLYCEROL, ... | | Authors: | Langley, D.B, Christ, D. | | Deposit date: | 2021-08-12 | | Release date: | 2022-03-02 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY).
Neuropeptides, 92, 2022
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4N1C
 | | Structural evidence for antigen receptor evolution | | Descriptor: | Lysozyme C, immunoglobulin variable light chain domain | | Authors: | Langley, D.B, Rouet, R, Roome, B, Stock, D, Christ, D. | | Deposit date: | 2013-10-03 | | Release date: | 2014-10-29 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural reconstruction of protein ancestry.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4N1E
 | | Structural evidence for antigen receptor evolution | | Descriptor: | Lysozyme C, immunoglobulin variable light chain domain | | Authors: | Langley, D.B, Rouet, R, Stock, D, Christ, D. | | Deposit date: | 2013-10-04 | | Release date: | 2014-10-29 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (2.23 Å) | | Cite: | Structural reconstruction of protein ancestry.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6DSI
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6DN0
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6D9I
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7T72
 | | Epitope-based selection of SARS-CoV-2 neutralizing antibodies from convalescent patients | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ... | | Authors: | Langley, D.B, Christ, D, Rouet, R. | | Deposit date: | 2021-12-14 | | Release date: | 2022-12-21 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (3.177 Å) | | Cite: | Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.
Nat Commun, 14, 2023
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7UEL
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7UEM
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7UEN
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7KZB
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7KZC
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7KZA
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7MSQ
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8CWI
 | | Fab arm of antibody 10G4 bound to CoV-2 receptor binding domain (RBD) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Heavy chain of Fab arm of antibody 10G4, ... | | Authors: | Langley, D.B, Christ, D. | | Deposit date: | 2022-05-19 | | Release date: | 2023-05-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.873 Å) | | Cite: | Neutralization of CoV-2 omicron lineages by affinity-matured class 5 antibodies
To Be Published
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8CWJ
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8CWK
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