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PDB: 69 件

2BT3
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AGAO in complex with Ruthenium-C4-wire at 1.73 angstroms
分子名称: BIS[1H,1'H-2,2'-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1'~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM, COPPER (II) ION, GLYCEROL, ...
著者Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B.
登録日2005-05-26
公開日2005-09-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Reversible Inhibition of Copper Amine Oxidase Activity by Channel-Blocking Ruthenium(II) and Rhenium(I) Molecular Wires.
Proc.Natl.Acad.Sci.USA, 102, 2005
5VJQ
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Complex between HyHEL10 Fab fragment heavy chain mutant (I29F, S52T, Y53F) and Pekin duck egg lysozyme isoform I (DEL-I)
分子名称: CHLORIDE ION, GLYCEROL, HyHEL10 heavy chain Fab fragment carrying three mutations; I29F, ...
著者Langley, D.B, Christ, D.
登録日2017-04-19
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.
Science, 360, 2018
1DUV
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BU of 1duv by Molmil
CRYSTAL STRUCTURE OF E. COLI ORNITHINE TRANSCARBAMOYLASE COMPLEXED WITH NDELTA-L-ORNITHINE-DIAMINOPHOSPHINYL-N-SULPHONIC ACID (PSORN)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, NDELTA-(N'-SULPHODIAMINOPHOSPHINYL)-L-ORNITHINE, ORNITHINE TRANSCARBAMOYLASE
著者Langley, D.B, Templeton, M.D, Fields, B.A, Mitchell, R.E, Collyer, C.A.
登録日2000-01-18
公開日2000-07-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of inactivation of ornithine transcarbamoylase by Ndelta -(N'-Sulfodiaminophosphinyl)-L-ornithine, a true transition state analogue? Crystal structure and implications for catalytic mechanism.
J.Biol.Chem., 275, 2000
4X4X
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BU of 4x4x by Molmil
Retrofitting antibodies with stabilizing mutations. Herceptin scFv mutant.
分子名称: Human Variable Heavy Chain of Herceptin, Human Variable Light Chain of Herceptin
著者Langley, D.B, Roome, B, Christ, D.
登録日2014-12-04
公開日2015-12-23
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Retrofitting antibodies with stabilizing mutations
To Be Published
4X4Z
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BU of 4x4z by Molmil
Retrofitting antibodies with stabilizing mutations. Herceptin VL mutant F53D.
分子名称: Herceptin VL domain with F53D mutation
著者Langley, D.B, Rouet, R, Christ, D.
登録日2014-12-04
公開日2015-12-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Retrofitting antibodies with stabilizing mutations
To Be Published
2ZCG
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BU of 2zcg by Molmil
Structure and inhibition of orotidine 5'-phosphate decarboxylase from plasmodium falciparum
分子名称: Orotidine 5'-phosphate decarboxylase
著者Langley, D.B, Guss, J.M, Shojaei, M, Christopherson, R.I.
登録日2007-11-08
公開日2008-03-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.223 Å)
主引用文献Structure and Inhibition of Orotidine 5'-Monophosphate Decarboxylase from Plasmodium falciparum
Biochemistry, 47, 2008
2ZP2
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C-terminal domain of KipI from Bacillus subtilis
分子名称: Kinase A inhibitor
著者Langley, D.B, Jacques, D.A.
登録日2008-06-24
公開日2009-01-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Histidine kinase regulation by a cyclophilin-like inhibitor
J.Mol.Biol., 384, 2008
7RTA
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BU of 7rta by Molmil
Crystal structures of human PYY and NPY
分子名称: 4A3B2-B Fab heavy chain, 4A3B2-B Fab light chain, Neuropeptide Y, ...
著者Langley, D.B, Christ, D.
登録日2021-08-12
公開日2022-03-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY).
Neuropeptides, 92, 2022
7RT9
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Crystal structures of human PYY and NPY
分子名称: 4A3B2-A Fab heavy chain, 4A3B2-A Fab light chain, GLYCEROL, ...
著者Langley, D.B, Christ, D.
登録日2021-08-12
公開日2022-03-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY).
Neuropeptides, 92, 2022
4N1C
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BU of 4n1c by Molmil
Structural evidence for antigen receptor evolution
分子名称: Lysozyme C, immunoglobulin variable light chain domain
著者Langley, D.B, Rouet, R, Roome, B, Stock, D, Christ, D.
登録日2013-10-03
公開日2014-10-29
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural reconstruction of protein ancestry.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4N1E
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BU of 4n1e by Molmil
Structural evidence for antigen receptor evolution
分子名称: Lysozyme C, immunoglobulin variable light chain domain
著者Langley, D.B, Rouet, R, Stock, D, Christ, D.
登録日2013-10-04
公開日2014-10-29
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural reconstruction of protein ancestry.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6DSI
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BU of 6dsi by Molmil
Anti recombinant prolactin receptor scFv
分子名称: Anti-TN-C scFv
著者Langley, D.B, Rouet, R, Christ, D.
登録日2018-06-14
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Anti recombinant prolactin receptor scFv
To Be Published
6DN0
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BU of 6dn0 by Molmil
Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D.
分子名称: FORMIC ACID, Human Variable Heavy Chain of Herceptin containing VH mutation K30D, Human Variable Light Chain of Herceptin containing VL mutation S52D
著者Langley, D.B, Roome, B, Christ, D.
登録日2018-06-05
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Retrofitting antibodies with stabilizing mutations
To Be Published
6D9I
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BU of 6d9i by Molmil
Pekin duck egg lysozyme isoform II (DEL-II)
分子名称: CHLORIDE ION, Lysozyme, MAGNESIUM ION
著者Langley, D.B, Christ, D.
登録日2018-04-30
公開日2018-09-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal structure of duck egg lysozyme isoform II (DEL-II).
BMC Struct. Biol., 18, 2018
7T72
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Epitope-based selection of SARS-CoV-2 neutralizing antibodies from convalescent patients
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, Antibody light chain, ...
著者Langley, D.B, Christ, D, Rouet, R.
登録日2021-12-14
公開日2022-12-21
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.177 Å)
主引用文献Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.
Nat Commun, 14, 2023
7UEL
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BU of 7uel by Molmil
Genetic and structural basis for the human anti-alpha-galactosyl antibody response
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Heavy chain Fab of antibody JEC1, ...
著者Langley, D.B, Christ, D.
登録日2022-03-22
公開日2022-06-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Genetic and structural basis of the human anti-alpha-galactosyl antibody response.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UEM
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BU of 7uem by Molmil
Genomic and structural basis for the human anti-alpha-galactosyl antibody response
分子名称: CHLORIDE ION, Heavy chain Fab arm of antibody HKB7, Light chain Fab of antibody HKB7, ...
著者Langley, D.B, Christ, D.
登録日2022-03-22
公開日2022-06-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.314 Å)
主引用文献Genetic and structural basis of the human anti-alpha-galactosyl antibody response.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UEN
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BU of 7uen by Molmil
Genetic and structural basis of the human anti-alpha-galactosyl antibody response
分子名称: M86 antibody Fab heavy chain, M86 antibody Fab light chain, PHOSPHATE ION, ...
著者Langley, D.B, Christ, D.
登録日2022-03-22
公開日2022-06-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Genetic and structural basis of the human anti-alpha-galactosyl antibody response.
Proc.Natl.Acad.Sci.USA, 119, 2022
7KZB
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BU of 7kzb by Molmil
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Fab heavy chain of CR3014-C8 antibody, ...
著者Langley, D.B, Christ, D.
登録日2020-12-10
公開日2021-02-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies.
Mabs, 13
7KZC
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BU of 7kzc by Molmil
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
分子名称: CHLORIDE ION, Fab heavy chain of m396-B10 antibody, Fab light chain of m396-B10 antibody
著者Langley, D.B, Christ, D.
登録日2020-12-10
公開日2021-02-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies.
Mabs, 13
7KZA
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BU of 7kza by Molmil
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
分子名称: CHLORIDE ION, Fab fragment heavy chain of anti-CoV2-RBD antibody variant CR3022-B6, Fab fragment light chain of anti-CoV2-RBD antibody variant CR3022-B6, ...
著者Langley, D.B, Christ, D.
登録日2020-12-10
公開日2021-02-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies.
Mabs, 13
7MSQ
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BU of 7msq by Molmil
Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD)
分子名称: AB-3467 Fab Heavy Chain, AB-3467 Fab Light Chain, CHLORIDE ION, ...
著者Langley, D.B, Christ, D.
登録日2021-05-12
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.
Immunity, 54, 2021
8CWI
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BU of 8cwi by Molmil
Fab arm of antibody 10G4 bound to CoV-2 receptor binding domain (RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Heavy chain of Fab arm of antibody 10G4, ...
著者Langley, D.B, Christ, D.
登録日2022-05-19
公開日2023-05-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.873 Å)
主引用文献Neutralization of CoV-2 omicron lineages by affinity-matured class 5 antibodies
To Be Published
8CWJ
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BU of 8cwj by Molmil
Fab arms of antibodies 4C12-B12 and CR3022 bound to pangolin receptor binding domain (pRBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Langley, D.B, Christ, D.
登録日2022-05-19
公開日2023-05-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.449 Å)
主引用文献Neutralization of CoV-2 omicron lineages by affinity-matured class 5 antibodies
To Be Published
8CWK
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BU of 8cwk by Molmil
Fab arm of antibodies 4G1-C2 and 10G4 bound to CoV-2 receptor binding domain (RBD)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Heavy chain of Fab arm of antibody 10G4, ...
著者Langley, D.B, Christ, D.
登録日2022-05-19
公開日2023-05-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.368 Å)
主引用文献Neutralization of CoV-2 omicron sublineages by affinity-matured class 5 antibodies
To Be Published

 

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