5WKZ
 
 | | VH1-69 germline antibody predicted from CR6261 | | 分子名称: | Immunoglobulin heavy variable 1-69D,IgG H chain, Lambda-chain (AA -20 to 215), SULFATE ION | | 著者 | Lang, S, Lee, P.S. | | 登録日 | 2017-07-25 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Anti-idiotypic antibody K1-18 engages VH1-69 precursor and affinity-matured, anti-stem antibodies through mimicry of the HA stem
To Be Published
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1ZSH
 | | Crystal structure of bovine arrestin-2 in complex with inositol hexakisphosphate (IP6) | | 分子名称: | Beta-arrestin 1, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION | | 著者 | Milano, S.K, Kim, Y.M, Stefano, F.P, Benovic, J.L, Brenner, C. | | 登録日 | 2005-05-24 | | 公開日 | 2006-01-31 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding
J.Biol.Chem., 281, 2006
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6RL1
 | | The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinotriose | | 分子名称: | Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ... | | 著者 | Lansky, S, Salama, R, Shoham, Y, Shoham, G. | | 登録日 | 2019-05-01 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
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7REN
 | | Room temperature serial crystal structure of Glutaminase C in complex with inhibitor UPGL-00004 | | 分子名称: | 2-phenyl-N-{5-[4-({5-[(phenylacetyl)amino]-1,3,4-thiadiazol-2-yl}amino)piperidin-1-yl]-1,3,4-thiadiazol-2-yl}acetamide, Glutaminase kidney isoform, mitochondrial | | 著者 | Milano, S.K, Finke, A, Cerione, R.A. | | 登録日 | 2021-07-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography.
J.Biol.Chem., 298, 2022
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7RGG
 | | Room temperature serial crystal structure of Glutaminase C in complex with inhibitor BPTES | | 分子名称: | Glutaminase kidney isoform, mitochondrial 68 kDa chain, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide) | | 著者 | Milano, S.K, Finke, A, Cerione, R.A. | | 登録日 | 2021-07-15 | | 公開日 | 2022-05-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | New insights into the molecular mechanisms of glutaminase C inhibitors in cancer cells using serial room temperature crystallography.
J.Biol.Chem., 298, 2022
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5HO0
 | | Crystal structure of AbnA (closed conformation), a GH43 extracellular arabinanase from Geobacillus stearothermophilus | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Lansky, S, Shwartstien, S, Salama, R, Shoham, Y, Shoham, G. | | 登録日 | 2016-01-19 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of AbnA (closed conformation), a GH43 extracellular arabinanase from Geobacillus stearothermophilus
To Be Published
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4HF2
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6RJY
 | | The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinobiose | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Arabino-oligosaccharids-binding protein, CALCIUM ION, ... | | 著者 | Lansky, S, Salama, R, Shoham, Y, Shoham, G. | | 登録日 | 2019-04-29 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.621 Å) | | 主引用文献 | Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
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6RKL
 | | The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinoheptaose | | 分子名称: | Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ... | | 著者 | Lansky, S, Salama, R, Shoham, Y, Shoham, G. | | 登録日 | 2019-04-30 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
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4HF0
 | | Crystal Structure of Apo IscR | | 分子名称: | HTH-type transcriptional regulator IscR, SULFATE ION | | 著者 | Rajagopalan, S.R, Phillips, K.J. | | 登録日 | 2012-10-04 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity.
Nat.Struct.Mol.Biol., 20, 2013
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4YRU
 | | Crystal structure of C-terminally truncated Neuronal Calcium Sensor (NCS-1) from Rattus norvegicus | | 分子名称: | CALCIUM ION, Neuronal calcium sensor 1 | | 著者 | Pandalaneni, S, Karrupiah, V, Mayans, O, Derrick, J.P, Lian, L.Y. | | 登録日 | 2015-03-15 | | 公開日 | 2015-04-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions.
J.Biol.Chem., 290, 2015
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6RL2
 | | The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinotetraose | | 分子名称: | Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ... | | 著者 | Lansky, S, Salama, R, Shoham, Y, Shoham, G. | | 登録日 | 2019-05-01 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
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6RKX
 | | The crystal structure of AbnE, an arabino-oligosaccharide binding protein, in complex with arabinopentaose | | 分子名称: | Arabino-oligosaccharids-binding protein, CALCIUM ION, GLYCEROL, ... | | 著者 | Lansky, S, Salama, R, Shoham, Y, Shoham, G. | | 登録日 | 2019-04-30 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.094 Å) | | 主引用文献 | Carbohydrate-Binding Capability and Functional Conformational Changes of AbnE, an Arabino-oligosaccharide Binding Protein.
J.Mol.Biol., 432, 2020
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4HF1
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4ZFM
 | | Structure of Gan1D-E170Q in complex with cellobiose-6-phosphate | | 分子名称: | 1,5-anhydro-6-O-phosphono-D-glucitol, 1,5-anhydro-6-O-phosphono-D-glucitol-(1-4)-beta-D-glucopyranose, 6-O-phosphono-beta-D-glucopyranose, ... | | 著者 | Lansky, S, Zehavi, A, Dvir, H, Shoham, Y, Shoham, G. | | 登録日 | 2015-04-21 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of Gan1D-E170Q in complex with cellobiose-6-phosphate
To Be Published
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4NX0
 | | Crystal structure of Abp-WT, a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus | | 分子名称: | Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ... | | 著者 | Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G. | | 登録日 | 2013-12-08 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6
Acta Crystallogr.,Sect.D, 70, 2014
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4NZF
 | | Crystal structure of Abp-D197A (a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus), in complex with arabinose | | 分子名称: | Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ... | | 著者 | Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G. | | 登録日 | 2013-12-12 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6
Acta Crystallogr.,Sect.D, 70, 2014
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4NXK
 | | Crystal structure of Abp-D197A, a catalytic mutant of a GH27-b-L-arabinopyranosidase from Geobacillus stearothermophilus | | 分子名称: | Abp, a GH27 beta-L-arabinopyranosidase, CITRIC ACID, ... | | 著者 | Lansky, S, Solomon, H.V, Salama, R, Belrhali, H, Shoham, Y, Shoham, G. | | 登録日 | 2013-12-09 | | 公開日 | 2014-12-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure-specificity relationships in Abp, a GH27 beta-L-arabinopyranosidase from Geobacillus stearothermophilus T6
Acta Crystallogr.,Sect.D, 70, 2014
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5XTU
 | | Crystal Structure of GDSL Esterase of Photobacterium sp. J15 | | 分子名称: | 1,2-ETHANEDIOL, CACODYLATE ION, CALCIUM ION, ... | | 著者 | Mazlan, S.N.H.S, Jonet, M.A, Leow, T.C, Ali, M.S.M, Rahman, R.N.Z.R.A. | | 登録日 | 2017-06-21 | | 公開日 | 2018-10-10 | | 最終更新日 | 2018-10-17 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Crystallization and structure elucidation of GDSL esterase of Photobacterium sp. J15.
Int. J. Biol. Macromol., 119, 2018
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3T03
 | | Crystal structure of PPAR gamma ligand binding domain in complex with a novel partial agonist GQ-16 | | 分子名称: | (5Z)-5-(5-bromo-2-methoxybenzylidene)-3-(4-methylbenzyl)-1,3-thiazolidine-2,4-dione, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma | | 著者 | Rajagopalan, S, Webb, P, Baxter, J.D, Brennan, R.G, Phillips, K.J. | | 登録日 | 2011-07-19 | | 公開日 | 2012-05-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | GQ-16, a novel peroxisome proliferator-activated receptor (PPAR gamma) ligand, promotes insulin sensitization without weight gain.
J.Biol.Chem., 287, 2012
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2B77
 | | Human transthyretin (TTR) complexed with Diflunisal analogues- TTR.2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID | | 分子名称: | 2',4'-DICHLORO-4-HYDROXY-1,1'-BIPHENYL-3-CARBOXYLIC ACID, Transthyretin | | 著者 | Palaninathan, S.K, Kelly, J.W, Sacchettini, J.C. | | 登録日 | 2005-10-03 | | 公開日 | 2005-10-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis.
J.Med.Chem., 47, 2004
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2B9A
 | | Human transthyretin (TTR) complexed with diflunisal analogues- TTR.3',5'-difluorobiphenyl-4-carboxylic acid | | 分子名称: | 3',5'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID, Transthyretin | | 著者 | Palaninathan, S.K, Kelly, J.W, Sacchettini, J.C. | | 登録日 | 2005-10-11 | | 公開日 | 2005-10-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Diflunisal Analogues Stabilize the Native State of Transthyretin. Potent Inhibition of Amyloidogenesis.
J.Med.Chem., 47, 2004
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3D2T
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2FLM
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2FBR
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