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PDB: 250 件

5J45
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Crystal structure of Shrub, fly ortholog of SNF7/CHMP4B
分子名称: GH13992p
著者McMillan, B.J, Blacklow, S.C.
登録日2016-03-31
公開日2016-07-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Electrostatic Interactions between Elongated Monomers Drive Filamentation of Drosophila Shrub, a Metazoan ESCRT-III Protein.
Cell Rep, 16, 2016
1HOP
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BU of 1hop by Molmil
STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI AT PH 6.5 AND 25 DEGREES CELSIUS
分子名称: ADENYLOSUCCINATE SYNTHETASE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Poland, B.W, Hou, Z, Bruns, C, Fromm, H.J, Honzatko, R.B.
登録日1996-04-26
公開日1996-11-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined crystal structures of guanine nucleotide complexes of adenylosuccinate synthetase from Escherichia coli.
J.Biol.Chem., 271, 1996
1HOO
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STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI AT PH 6.5 AND 25 DEGREES CELSIUS
分子名称: ADENYLOSUCCINATE SYNTHETASE, AMINOPHOSPHONIC ACID-GUANYLATE ESTER, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Poland, B.W, Hou, Z, Bruns, C, Fromm, H.J, Honzatko, R.B.
登録日1996-04-26
公開日1997-02-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined crystal structures of guanine nucleotide complexes of adenylosuccinate synthetase from Escherichia coli.
J.Biol.Chem., 271, 1996
6MHU
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BU of 6mhu by Molmil
Nucleotide-free Cryo-EM Structure of E.coli LptB2FG Transporter
分子名称: (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-5-[(2~{S},3~{S},4~{R},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{R},5~{S},6~{R})-6-[(1~{S})-2-[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-1-oxidanyl-ethyl]-3,4-bis(oxidanyl)-5-phosphonooxy-oxan-2-yl]oxy-3-oxidanyl-5-phosphonooxy-oxan-2-yl]oxy-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ...
著者Orlando, B.J, Li, Y, Liao, M.
登録日2018-09-18
公開日2019-04-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
6MI8
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Cryo-EM Structure of vanadate-trapped E.coli LptB2FGC
分子名称: ADP ORTHOVANADATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ...
著者Orlando, B.J, Li, Y, Liao, M.
登録日2018-09-19
公開日2019-04-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
6MHZ
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Vanadate trapped Cryo-EM Structure of E.coli LptB2FG Transporter
分子名称: ADP ORTHOVANADATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ...
著者Orlando, B.J, Li, Y, Liao, M.
登録日2018-09-18
公開日2019-04-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
6MI7
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Nucleotide-free Cryo-EM Structure of E.coli LptB2FGC
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ...
著者Orlando, B.J, Li, Y, Liao, M.
登録日2018-09-19
公開日2019-04-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of lipopolysaccharide extraction by the LptB2FGC complex.
Nature, 567, 2019
6NJ8
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Encapsulin iron storage compartment from Quasibacillus thermotolerans
分子名称: Encapsulating protein for a DyP-type peroxidase, targeting peptide
著者Orlando, B.J, Giessen, T.W, Chambers, M.G, Liao, M, Silver, P.A.
登録日2019-01-02
公開日2019-08-07
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Large protein organelles form a new iron sequestration system with high storage capacity.
Elife, 8, 2019
6H02
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BU of 6h02 by Molmil
Crystal structure of human Mediator subunit MED23
分子名称: LAMA nanobody NB106, Mediator of RNA polymerase II transcription subunit 23
著者Clantin, B, Monte, D, Villeret, V.
登録日2018-07-06
公開日2018-08-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human Mediator subunit MED23.
Nat Commun, 9, 2018
3QDO
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BU of 3qdo by Molmil
Crystal Structure of PDZ domain of sorting nexin 27 (SNX27) fused to the Gly-Gly linker followed by C-terminal (ESESKV) of GIRK3
分子名称: Sorting nexin-27, G protein-activated inward rectifier potassium channel 3 chimera
著者Balana, B, Kwiatkowski, W, Choe, S.
登録日2011-01-18
公開日2011-03-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27.
Proc.Natl.Acad.Sci.USA, 108, 2011
3NJT
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BU of 3njt by Molmil
Crystal structure of the R450A mutant of the membrane protein FhaC
分子名称: Filamentous hemagglutinin transporter protein fhaC
著者Clantin, B, Delattre, A.S, Jacob-Dubuisson, F, Villeret, V.
登録日2010-06-18
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Functional importance of a conserved sequence motif in FhaC, a prototypic member of the TpsB/Omp85 superfamily.
Febs J., 277, 2010
7M05
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BU of 7m05 by Molmil
CryoEM structure of PRMT5 bound to covalent PBM-site inhibitor BRD-6988
分子名称: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-{[2-(pyridin-2-yl)ethyl]sulfamoyl}phenyl)acetamide, Methylosome protein 50, Protein arginine N-methyltransferase 5
著者McMillan, B.J, McKinney, D.C, Timm, D.E.
登録日2021-03-10
公開日2021-03-17
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
J.Med.Chem., 64, 2021
3QE1
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BU of 3qe1 by Molmil
Crystal Structure of PDZ domain of sorting nexin 27 (SNX27) fused to the C-terminal residues (ESESKV) of GIRK3
分子名称: Sorting nexin-27, G protein-activated inward rectifier potassium channel 3 chimera
著者Balana, B, Kwiatkowski, W, Choe, S.
登録日2011-01-19
公開日2011-03-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27.
Proc.Natl.Acad.Sci.USA, 108, 2011
1EF0
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BU of 1ef0 by Molmil
CRYSTAL STRUCTURE OF PI-SCEI MINIPRECURSOR
分子名称: PI-SCEI ENDONUCLEASE, ZINC ION
著者Poland, B.W, Xu, M.-Q, Quiocho, F.A.
登録日2000-02-04
公開日2000-06-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into the protein splicing mechanism of PI-SceI.
J.Biol.Chem., 275, 2000
6V0O
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BU of 6v0o by Molmil
PRMT5 bound to the PBM peptide from pICln
分子名称: ACETYL GROUP, Methylosome protein 50, PBM peptide, ...
著者McMillan, B.J, Raymond, D.D.
登録日2019-11-19
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Molecular basis for substrate recruitment to the PRMT5 methylosome.
Mol.Cell, 81, 2021
4XI7
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BU of 4xi7 by Molmil
Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with Jagged1 N-box peptide
分子名称: E3 ubiquitin-protein ligase MIB1, Jagged 1 N-box peptide, SULFATE ION, ...
著者McMillan, B.J, Blacklow, S.C.
登録日2015-01-06
公開日2015-03-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.051 Å)
主引用文献A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
6VXF
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BU of 6vxf by Molmil
Structure of apo-closed ABCG2
分子名称: Broad substrate specificity ATP-binding cassette transporter ABCG2
著者Orlando, B.J, Maofu, L.
登録日2020-02-21
公開日2020-05-13
最終更新日2020-05-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
4XIB
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BU of 4xib by Molmil
Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with fly Delta N-box peptide
分子名称: Delta N-box peptide, E3 ubiquitin-protein ligase MIB1, SULFATE ION, ...
著者McMillan, B.J, Blacklow, S.C.
登録日2015-01-06
公開日2015-03-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
4XI6
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BU of 4xi6 by Molmil
Crystal structure of the MZM-REP domains of Mind bomb 1
分子名称: E3 ubiquitin-protein ligase MIB1, SULFATE ION, ZINC ION
著者McMillan, B.J, Blacklow, S.C.
登録日2015-01-06
公開日2015-03-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
7K81
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KIR3DL1*005 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, Beta-2-microglobulin, ...
著者MacLachlan, B.J, Rossjohn, J, Vivian, J.P.
登録日2020-09-24
公開日2020-12-09
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.
J Immunol., 206, 2021
7K80
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KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ARG-TYR-PRO-LEU-THR-PHE-GLY-TRP, ...
著者MacLachlan, B.J, Rossjohn, J, Vivian, J.P.
登録日2020-09-24
公開日2020-12-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.
J Immunol., 206, 2021
8PJF
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BU of 8pjf by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR
分子名称: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
著者MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J.
登録日2023-06-23
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation.
Cell Rep, 43, 2024
8CMF
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Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 nsp3 epitope (orf1ab)1350-1364
分子名称: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMD
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BU of 8cmd by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S761-775
分子名称: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMH
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BU of 8cmh by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Omicron (BA.1) Spike peptide S486-505
分子名称: 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, HLA class II histocompatibility antigen, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023

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