4QNW
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6QEX
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6QEE
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4IPY
| HIV capsid C-terminal domain | Descriptor: | 1,2-ETHANEDIOL, Capsid protein p24 | Authors: | Lampel, A, Yaniv, O, Berger, O, Bachrach, E, Gazit, E, Frolow, F. | Deposit date: | 2013-01-10 | Release date: | 2013-10-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | A triclinic crystal structure of the carboxy-terminal domain of HIV-1 capsid protein with four molecules in the asymmetric unit reveals a novel packing interface. Acta Crystallogr.,Sect.F, 69, 2013
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4GMF
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4GMG
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4HT1
| Human TWEAK in complex with the Fab fragment of a neutralizing antibody | Descriptor: | Tumor necrosis factor ligand superfamily member 12, chimeric antibody Fab | Authors: | Lammens, A. | Deposit date: | 2012-10-31 | Release date: | 2013-06-12 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Crystal Structure of Human TWEAK in Complex with the Fab Fragment of a Neutralizing Antibody Reveals Insights into Receptor Binding. Plos One, 8, 2013
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1DO5
| HUMAN COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE DOMAIN II | Descriptor: | HUMAN COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE DOMAIN II, ZINC ION | Authors: | Lamb, A.L, Wernimont, A.K, Pufahl, R.A, O'Halloran, T.V, Rosenzweig, A.C. | Deposit date: | 1999-12-18 | Release date: | 2000-12-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of the second domain of the human copper chaperone for superoxide dismutase. Biochemistry, 39, 2000
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1JK9
| Heterodimer between H48F-ySOD1 and yCCS | Descriptor: | SULFATE ION, ZINC ION, copper chaperone for superoxide dismutase, ... | Authors: | Lamb, A.L, Torres, A.S, O'Halloran, T.V, Rosenzweig, A.C. | Deposit date: | 2001-07-11 | Release date: | 2001-09-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Heterodimeric structure of superoxide dismutase in complex with its metallochaperone. Nat.Struct.Biol., 8, 2001
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8EEB
| Cryo-EM structure of human ABCA7 in Digitonin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phospholipid-transporting ATPase ABCA7, ... | Authors: | Alam, A, Le, L.T.M, Thompson, J.R. | Deposit date: | 2022-09-06 | Release date: | 2022-12-21 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms. Embo J., 42, 2023
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8EOP
| Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Alam, A, Le, L.T.M, Thompson, J.R. | Deposit date: | 2022-10-04 | Release date: | 2022-12-21 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms. Embo J., 42, 2023
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8EE6
| Cryo-EM Structure of human ABCA7 in PE/Ch nanodiscs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Phospholipid-transporting ATPase ABCA7, ... | Authors: | Alam, A, Le, L.T.M, Thompson, J.R. | Deposit date: | 2022-09-06 | Release date: | 2022-12-21 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms. Embo J., 42, 2023
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8EDW
| Cryo-EM Structure of human ABCA7 in BPL/Ch Nanodiscs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Alam, A, Le, L.T.M, Thompson, J.R. | Deposit date: | 2022-09-06 | Release date: | 2022-12-21 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms. Embo J., 42, 2023
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1XEX
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1T11
| Trigger Factor | Descriptor: | Trigger factor | Authors: | Ludlam, A.V, Moore, B.A, Xu, Z. | Deposit date: | 2004-04-14 | Release date: | 2004-09-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of ribosomal chaperone trigger factor from Vibrio cholerae. Proc.Natl.Acad.Sci.USA, 101, 2004
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7SVN
| DPP9 IN COMPLEX WITH LIGAND ICeD-1 | Descriptor: | (2S,4S)-1-[(2S)-2-amino-2-cyclohexylacetyl]-4-fluoropyrrolidine-2-carbonitrile, Dipeptidyl peptidase 9 | Authors: | Lammens, A, Hollenstein, K, Klein, D.J. | Deposit date: | 2021-11-19 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells. Acs Chem.Biol., 17, 2022
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7SVM
| DPP8 IN COMPLEX WITH LIGAND ICeD-2 | Descriptor: | (2S)-2-amino-1-(1,3-dihydro-2H-isoindol-2-yl)-2-[(1r,4S)-4-(pyrrolidin-1-yl)cyclohexyl]ethan-1-one, Dipeptidyl peptidase 8, trimethylamine oxide | Authors: | Lammens, A, Hollenstein, K, Klein, D.J. | Deposit date: | 2021-11-19 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells. Acs Chem.Biol., 17, 2022
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7SVO
| DPP8 IN COMPLEX WITH LIGAND ICeD-1 | Descriptor: | (2S,4S)-1-[(2S)-2-amino-2-cyclohexylacetyl]-4-fluoropyrrolidine-2-carbonitrile, Dipeptidyl peptidase 8, trimethylamine oxide | Authors: | Lammens, A, Hollenstein, K, Klein, D.J. | Deposit date: | 2021-11-19 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells. Acs Chem.Biol., 17, 2022
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7SVL
| DPP9 IN COMPLEX WITH LIGAND ICeD-2 | Descriptor: | (2S)-2-amino-1-(1,3-dihydro-2H-isoindol-2-yl)-2-[(1r,4S)-4-(pyrrolidin-1-yl)cyclohexyl]ethan-1-one, Dipeptidyl peptidase 9 | Authors: | Lammens, A, Hollenstein, K, Klein, D.J. | Deposit date: | 2021-11-19 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells. Acs Chem.Biol., 17, 2022
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1XEW
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1FW5
| SOLUTION STRUCTURE OF MEMBRANE BINDING PEPTIDE OF SEMLIKI FOREST VIRUS MRNA CAPPING ENZYME NSP1 | Descriptor: | NONSTRUCTURAL PROTEIN NSP1 | Authors: | Lampio, A, Kilpelinen, I, Pesonen, S, Karhi, K, Auvinen, P, Somerharju, P, Kriinen, L. | Deposit date: | 2000-09-21 | Release date: | 2001-09-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Membrane binding mechanism of an RNA virus-capping enzyme. J.Biol.Chem., 275, 2001
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2H9D
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2R31
| Crystal structure of atp12p from paracoccus denitrificans | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP12 ATPase | Authors: | Ludlam, A.V, Brunzelle, J.S, Gatti, D.L, Ackerman, S.H. | Deposit date: | 2007-08-28 | Release date: | 2008-03-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Chaperones of F1-ATPase. J.Biol.Chem., 284, 2009
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2H9C
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6TCU
| Glycogen synthase kinase-3 beta (GSK3b) in complex with ligand 1 | Descriptor: | 5-[2,3-bis(fluoranyl)phenyl]-~{N}-[[1-(2-methoxyethyl)piperidin-4-yl]methyl]-1~{H}-indazole-3-carboxamide, ACETATE ION, Glycogen synthase kinase-3 beta | Authors: | Lammens, A, Krapp, S, Buonfiglio, R, Ombrato, R. | Deposit date: | 2019-11-06 | Release date: | 2020-09-16 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Optimization of Indazole-Based GSK-3 Inhibitors with Mitigated hERG Issue andIn VivoActivity in a Mood Disorder Model. Acs Med.Chem.Lett., 11, 2020
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