4QNW
 
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1FW5
 | | SOLUTION STRUCTURE OF MEMBRANE BINDING PEPTIDE OF SEMLIKI FOREST VIRUS MRNA CAPPING ENZYME NSP1 | | 分子名称: | NONSTRUCTURAL PROTEIN NSP1 | | 著者 | Lampio, A, Kilpelinen, I, Pesonen, S, Karhi, K, Auvinen, P, Somerharju, P, Kriinen, L. | | 登録日 | 2000-09-21 | | 公開日 | 2001-09-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Membrane binding mechanism of an RNA virus-capping enzyme.
J.Biol.Chem., 275, 2001
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1DO5
 | | HUMAN COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE DOMAIN II | | 分子名称: | HUMAN COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE DOMAIN II, ZINC ION | | 著者 | Lamb, A.L, Wernimont, A.K, Pufahl, R.A, O'Halloran, T.V, Rosenzweig, A.C. | | 登録日 | 1999-12-18 | | 公開日 | 2000-12-18 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structure of the second domain of the human copper chaperone for superoxide dismutase.
Biochemistry, 39, 2000
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4IPY
 | | HIV capsid C-terminal domain | | 分子名称: | 1,2-ETHANEDIOL, Capsid protein p24 | | 著者 | Lampel, A, Yaniv, O, Berger, O, Bachrach, E, Gazit, E, Frolow, F. | | 登録日 | 2013-01-10 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | A triclinic crystal structure of the carboxy-terminal domain of HIV-1 capsid protein with four molecules in the asymmetric unit reveals a novel packing interface.
Acta Crystallogr.,Sect.F, 69, 2013
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1QDS
 | | SUPERSTABLE E65Q MUTANT OF LEISHMANIA MEXICANA TRIOSEPHOSPHATE ISOMERASE (TIM) | | 分子名称: | 2-PHOSPHOGLYCOLIC ACID, TRIOSEPHOSPHATE ISOMERASE | | 著者 | Lambeir, A.M, Backmann, J, Ruiz-Sanz, J, Filimonov, V, Nielsen, J.E, Vriend, G, Kursula, I, Norledge, B.V, Wierenga, R.K. | | 登録日 | 1999-07-10 | | 公開日 | 2000-12-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase.
Eur.J.Biochem., 267, 2000
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1QUP
 | | CRYSTAL STRUCTURE OF THE COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE | | 分子名称: | SULFATE ION, SUPEROXIDE DISMUTASE 1 COPPER CHAPERONE | | 著者 | Lamb, A.L, Wernimont, A.K, Pufahl, R.A, O'Halloran, T.V, Rosenzweig, A.C. | | 登録日 | 1999-07-01 | | 公開日 | 1999-12-10 | | 最終更新日 | 2018-06-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the copper chaperone for superoxide dismutase.
Nat.Struct.Biol., 6, 1999
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4HT1
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8EEB
 | | Cryo-EM structure of human ABCA7 in Digitonin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phospholipid-transporting ATPase ABCA7, ... | | 著者 | Alam, A, Le, L.T.M, Thompson, J.R. | | 登録日 | 2022-09-06 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
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6W3K
 | | Structure of unphosphorylated human IRE1 bound to G-9807 | | 分子名称: | 4-[5-[2,6-bis(fluoranyl)phenyl]-2~{H}-pyrazolo[3,4-b]pyridin-3-yl]-2-(4-oxidanylpiperidin-1-yl)-1~{H}-pyrimidin-6-one, Serine/threonine-protein kinase/endoribonuclease IRE1 | | 著者 | Lammens, A, Wang, W, Ferri, E, Rudolph, J. | | 登録日 | 2020-03-09 | | 公開日 | 2020-12-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands.
Nat Commun, 11, 2020
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8EE6
 | | Cryo-EM Structure of human ABCA7 in PE/Ch nanodiscs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Phospholipid-transporting ATPase ABCA7, ... | | 著者 | Alam, A, Le, L.T.M, Thompson, J.R. | | 登録日 | 2022-09-06 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
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8EDW
 | | Cryo-EM Structure of human ABCA7 in BPL/Ch Nanodiscs | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Alam, A, Le, L.T.M, Thompson, J.R. | | 登録日 | 2022-09-06 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
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8EOP
 | | Cryo-EM Structure of Nanodisc reconstituted human ABCA7 EQ mutant in ATP bound closed state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Alam, A, Le, L.T.M, Thompson, J.R. | | 登録日 | 2022-10-04 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-02-15 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryo-EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms.
Embo J., 42, 2023
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7SVM
 | | DPP8 IN COMPLEX WITH LIGAND ICeD-2 | | 分子名称: | (2S)-2-amino-1-(1,3-dihydro-2H-isoindol-2-yl)-2-[(1r,4S)-4-(pyrrolidin-1-yl)cyclohexyl]ethan-1-one, Dipeptidyl peptidase 8, trimethylamine oxide | | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | | 登録日 | 2021-11-19 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Acs Chem.Biol., 17, 2022
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7SVN
 | | DPP9 IN COMPLEX WITH LIGAND ICeD-1 | | 分子名称: | (2S,4S)-1-[(2S)-2-amino-2-cyclohexylacetyl]-4-fluoropyrrolidine-2-carbonitrile, Dipeptidyl peptidase 9 | | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | | 登録日 | 2021-11-19 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Acs Chem.Biol., 17, 2022
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7SVO
 | | DPP8 IN COMPLEX WITH LIGAND ICeD-1 | | 分子名称: | (2S,4S)-1-[(2S)-2-amino-2-cyclohexylacetyl]-4-fluoropyrrolidine-2-carbonitrile, Dipeptidyl peptidase 8, trimethylamine oxide | | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | | 登録日 | 2021-11-19 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Acs Chem.Biol., 17, 2022
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7SVL
 | | DPP9 IN COMPLEX WITH LIGAND ICeD-2 | | 分子名称: | (2S)-2-amino-1-(1,3-dihydro-2H-isoindol-2-yl)-2-[(1r,4S)-4-(pyrrolidin-1-yl)cyclohexyl]ethan-1-one, Dipeptidyl peptidase 9 | | 著者 | Lammens, A, Hollenstein, K, Klein, D.J. | | 登録日 | 2021-11-19 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Acs Chem.Biol., 17, 2022
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1XEX
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1T11
 | | Trigger Factor | | 分子名称: | Trigger factor | | 著者 | Ludlam, A.V, Moore, B.A, Xu, Z. | | 登録日 | 2004-04-14 | | 公開日 | 2004-09-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of ribosomal chaperone trigger factor from Vibrio cholerae.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1XEW
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2H9C
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2H9D
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6TCU
 | | Glycogen synthase kinase-3 beta (GSK3b) in complex with ligand 1 | | 分子名称: | 5-[2,3-bis(fluoranyl)phenyl]-~{N}-[[1-(2-methoxyethyl)piperidin-4-yl]methyl]-1~{H}-indazole-3-carboxamide, ACETATE ION, Glycogen synthase kinase-3 beta | | 著者 | Lammens, A, Krapp, S, Buonfiglio, R, Ombrato, R. | | 登録日 | 2019-11-06 | | 公開日 | 2020-09-16 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Optimization of Indazole-Based GSK-3 Inhibitors with Mitigated hERG Issue andIn VivoActivity in a Mood Disorder Model.
Acs Med.Chem.Lett., 11, 2020
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3I1C
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3KTA
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3C25
 | | Crystal Structure of NotI Restriction Endonuclease Bound to Cognate DNA | | 分子名称: | CALCIUM ION, DNA (5'-D(*DCP*DGP*DGP*DAP*DGP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DCP*DGP*DCP*DCP*DG)-3'), DNA (5'-D(*DCP*DGP*DGP*DCP*DGP*DGP*DCP*DGP*DCP*DGP*DGP*DCP*DCP*DGP*DCP*DGP*DCP*DCP*DTP*DCP*DCP*DG)-3'), ... | | 著者 | Lambert, A.R, Sussman, D, Shen, B, Stoddard, B.L. | | 登録日 | 2008-01-24 | | 公開日 | 2008-02-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding.
Structure, 16, 2008
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