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PDB: 6 results

6PW3
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BU of 6pw3 by Molmil
LARP1 DM15 FYRE (F844Y, R847E) mutant bound to m7GpppG dinucleotide (capG)
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, La-related protein 1, MAGNESIUM ION
Authors:Lahr, R.M, Berman, A.J.
Deposit date:2019-07-22
Release date:2019-11-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Capturing the Mechanism Underlying TOP mRNA Binding to LARP1.
Structure, 27, 2019
5C0V
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BU of 5c0v by Molmil
Structure of the LARP1-unique domain DM15
Descriptor: La-related protein 1, SULFATE ION
Authors:Lahr, R.M, Berman, A.J.
Deposit date:2015-06-12
Release date:2015-08-05
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence.
Nucleic Acids Res., 43, 2015
4ZC4
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BU of 4zc4 by Molmil
Crystal structure of LARP1-unique domain DM15
Descriptor: La-related protein 1, SULFATE ION
Authors:Lahr, R.M, Berman, A.J.
Deposit date:2015-04-15
Release date:2015-08-05
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence.
Nucleic Acids Res., 43, 2015
5V4R
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BU of 5v4r by Molmil
Crystal structure of LARP1-unique domain DM15 bound to m7GTP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, La-related protein 1
Authors:Berman, A.J, Lahr, R.M.
Deposit date:2017-03-10
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife, 6, 2017
5V7C
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BU of 5v7c by Molmil
Crystal structure of LARP1-unique domain DM15 bound 5'TOP RNA sequence
Descriptor: La-related protein 1, RNA (5'-R(*CP*UP*UP*UP*UP*CP*CP*G)-3')
Authors:Berman, A.J, Lahr, R.M, Al-Ashtal, H.A.
Deposit date:2017-03-20
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife, 6, 2017
5V87
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BU of 5v87 by Molmil
Crystal structure of LARP1-unique domain DM15 bound to m7GpppC
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, La-related protein 1, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate
Authors:Berman, A.J, Lahr, R.M.
Deposit date:2017-03-21
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.692 Å)
Cite:La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife, 6, 2017

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