2HY6
| A seven-helix coiled coil | Descriptor: | General control protein GCN4, HEXANE-1,6-DIOL | Authors: | Liu, J, Zheng, Q, Deng, Y, Cheng, C.S, Kallenbach, N.R, Lu, M. | Deposit date: | 2006-08-04 | Release date: | 2006-10-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | A seven-helix coiled coil. Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2OMJ
| solution structure of LARG PDZ domain | Descriptor: | Rho guanine nucleotide exchange factor 12 | Authors: | Liu, J, Huang, H, Hu, Q. | Deposit date: | 2007-01-22 | Release date: | 2008-01-22 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | solution structure and dynamics of the LARG PDZ domain To be Published
|
|
2OS6
| |
3TCP
| Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC569 | Descriptor: | 1-[(trans-4-aminocyclohexyl)methyl]-N-butyl-3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine, CALCIUM ION, CHLORIDE ION, ... | Authors: | Liu, J, Yang, C, Simpson, C, DeRyckere, D, Van Deusen, A, Miley, M, Kireev, D.B, Norris-Drouin, J, Sather, S, Hunter, D, Patel, H.S, Janzen, W.P, Machius, M, Johnson, G, Earp, H.S, Graham, D.K, Frye, S, Wang, X. | Deposit date: | 2011-08-09 | Release date: | 2012-06-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic Leukemia. ACS Med Chem Lett, 3, 2012
|
|
4IDV
| Crystal Structure of NIK with compound 4-{3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl}-2-methylbut-3-yn-2-ol (13V) | Descriptor: | 4-{3-[2-amino-5-(2-methoxyethoxy)pyrimidin-4-yl]-1H-indol-5-yl}-2-methylbut-3-yn-2-ol, Mitogen-activated protein kinase kinase kinase 14 | Authors: | Liu, J, Sudom, A, Wang, Z. | Deposit date: | 2012-12-13 | Release date: | 2013-04-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Inhibiting NF-KB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure activity relationship, and co-crystal structures Bioorg.Med.Chem.Lett., 23, 2013
|
|
3TO2
| Structure of HLA-A*0201 complexed with peptide Md3-C9 derived from a clustering region of restricted cytotoxic T lymphocyte epitope from SARS-CoV M protein | Descriptor: | Beta-2-microglobulin, MHC class I antigen, Md3-C9 peptide derived from Membrane glycoprotein | Authors: | Liu, J, Qi, J, Gao, F, Yan, J, Gao, G.F. | Deposit date: | 2011-09-03 | Release date: | 2012-08-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Functional and Structural Definition of a Clustering Region of HLA-A2-restricted Cytotoxic T Lymphocyte Epitopes Sci.Technology Rev., 29, 2011
|
|
2HZ5
| Crystal structure of human dynein light chain Dnlc2A | Descriptor: | CESIUM ION, Dynein light chain 2A, cytoplasmic | Authors: | Liu, J.-F, Wang, Z.-X, Wang, X.-Q, Tang, Q, An, X.-M, Gui, L.-L, Liang, D.-C. | Deposit date: | 2006-08-08 | Release date: | 2007-08-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of human dynein light chain Dnlc2A: Structural insights into the interaction with IC74 Biochem.Biophys.Res.Commun., 349, 2006
|
|
4HLR
| |
2LKO
| Structural Basis of Phosphoinositide Binding to Kindlin-2 Pleckstrin Homology Domain in Regulating Integrin Activation | Descriptor: | Fermitin family homolog 2, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE | Authors: | Liu, J, Fukuda, K, Xu, Z. | Deposit date: | 2011-10-17 | Release date: | 2011-10-26 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation. J.Biol.Chem., 286, 2011
|
|
4IDT
| Crystal Structure of NIK with 11-bromo-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine (T28) | Descriptor: | 11-bromo-5,6,7,8-tetrahydropyrimido[4',5':3,4]cyclohepta[1,2-b]indol-2-amine, Mitogen-activated protein kinase kinase kinase 14 | Authors: | Liu, J, Sudom, A, Wang, Z. | Deposit date: | 2012-12-13 | Release date: | 2013-04-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Inhibiting NF-KB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure activity relationship, and co-crystal structures Bioorg.Med.Chem.Lett., 23, 2013
|
|
3VBT
| |
3VBV
| |
3VBQ
| |
3VBY
| |
3VBW
| |
4LCY
| Crystal structure of HLA-b46 at 1.6 angstrom resolution | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-46 alpha chain, ... | Authors: | Liu, J.X. | Deposit date: | 2013-06-24 | Release date: | 2014-06-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure Analysis of the Human Leukocyte Antigen B*46:01 To be Published
|
|
3VBX
| |
3VC4
| |
5WEH
| Cytochrome c oxidase from Rhodobacter sphaeroides in the reduced state | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, Aa3-type cytochrome c oxidase subunit IV, CALCIUM ION, ... | Authors: | Liu, J, Ferguson-Miller, F, Ling, Q, Hiser, C. | Deposit date: | 2017-07-10 | Release date: | 2017-09-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Role of conformational change and K-path ligands in controlling cytochrome c oxidase activity. Biochem. Soc. Trans., 45, 2017
|
|
6KLY
| Crystal structure of the type III effector XopAI from Xanthomonas axonopodis pv. citri in space group P43212 | Descriptor: | Type III effector XopAI | Authors: | Liu, J.-H, Wu, J.E, Lin, H, Chiu, S.W, Yang, J.Y. | Deposit date: | 2019-07-30 | Release date: | 2019-08-21 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal Structure-Based Exploration of Arginine-Containing Peptide Binding in the ADP-Ribosyltransferase Domain of the Type III Effector XopAI Protein. Int J Mol Sci, 20, 2019
|
|
4OEA
| Crystal structure of AR-LBD | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor | Authors: | Liu, J.S, Hsu, C.L, Wu, W.G. | Deposit date: | 2014-01-12 | Release date: | 2014-08-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
|
|
4OFR
| Crystal structure of AR-LBD bound with co-regulator peptide | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, co-regulator peptide | Authors: | Liu, J.S, Hsu, C.L, Wu, W.G. | Deposit date: | 2014-01-15 | Release date: | 2014-08-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
|
|
4OFU
| Crystal structure of AR-LBD bound with co-regulator peptide | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, co-regulator peptide | Authors: | Liu, J.S, Hsu, C.L, Wu, W.G. | Deposit date: | 2014-01-15 | Release date: | 2014-08-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
|
|
2LSJ
| |
4OK1
| Crystal structure of W741L-AR-LBD bound with co-regulator peptide | Descriptor: | Androgen receptor, R-BICALUTAMIDE, co-regulator peptide | Authors: | Liu, J.S, Hsu, C.L, Wu, W.G. | Deposit date: | 2014-01-21 | Release date: | 2014-08-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
|
|