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PDB: 435 件
3R0M
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Crystal structure of anti-HIV llama VHH antibody A12
分子名称: Llama VHH A12, SULFATE ION
著者Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
登録日2011-03-08
公開日2012-03-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Single-Headed Immunoglobulins Efficiently Penetrate CD4-Binding Site and Effectively Neutralize HIV-1
To be Published
3PIQ
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BU of 3piq by Molmil
Crystal structure of human 2909 Fab, a quaternary structure-specific antibody against HIV-1
分子名称: Human monoclonal antibody 2909 Fab heavy chain, Human monoclonal antibody 2909 Fab light chain
著者Changela, A, Gorny, M.K, Zolla-Pazner, S, Kwong, P.D.
登録日2010-11-07
公開日2011-01-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.325 Å)
主引用文献Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1.
J.Virol., 85, 2011
3Q39
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BU of 3q39 by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type H2 (diglycan)
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-12-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3RPT
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BU of 3rpt by Molmil
Crystal structure of the anti-HIV b12 scaffold protein
分子名称: Endoglucanase E-2, SULFATE ION
著者Chen, L, Kwong, P.D.
登録日2011-04-27
公開日2011-12-21
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.303 Å)
主引用文献Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold.
Science, 334, 2011
3RJQ
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Crystal structure of anti-HIV llama VHH antibody A12 in complex with C186 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C186 gp120, Llama VHH A12
著者Chen, L, McLellan, J.S, Kwon, Y.D, Schmidt, S, Wu, X, Zhou, T, Yang, Y, Zhang, B, Forsman, A, Weiss, R.A, Verrips, T, Mascola, J, Kwong, P.D.
登録日2011-04-15
公開日2012-05-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Crystal structure of anti-HIV A12 VHH of llama antibody in complex with C1086 gp120
To be Published
3R6K
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BU of 3r6k by Molmil
Crystal Structure of the Capsid P Domain from Norwalk Virus Strain Hiroshima/1999 in complex with HBGA type B (triglycan)
分子名称: 1,2-ETHANEDIOL, VP1 protein, alpha-L-fucopyranose-(1-2)-[alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose
著者Hansman, G.S, Biertumpfel, C, McLellan, J.S, Georgiev, I, Chen, L, Zhou, T, Katayama, K, Kwong, P.D.
登録日2011-03-21
公開日2011-05-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability.
J.Virol., 85, 2011
3RRT
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BU of 3rrt by Molmil
Structure of the RSV F protein in the post-fusion conformation
分子名称: Fusion glycoprotein F0
著者McLellan, J.S, Yongping, Y, Graham, B.S, Kwong, P.D.
登録日2011-04-30
公開日2011-06-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.
J.Virol., 85, 2011
3RRR
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BU of 3rrr by Molmil
Structure of the RSV F protein in the post-fusion conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
著者McLellan, J.S, Yongping, Y, Graham, B.S, Kwong, P.D.
登録日2011-04-30
公開日2011-06-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.821 Å)
主引用文献Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.
J.Virol., 85, 2011
3RY8
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BU of 3ry8 by Molmil
Structural basis for norovirus inhibition and fucose mimicry by citrate
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, Capsid protein
著者Hansman, G.S, McLellan, J.S, Kwong, P.D.
登録日2011-05-11
公開日2011-11-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural basis for norovirus inhibition and fucose mimicry by citrate.
J.Virol., 86, 2012
3PA1
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BU of 3pa1 by Molmil
Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with HBGA type A
分子名称: 1,2-ETHANEDIOL, Capsid protein, IMIDAZOLE, ...
著者Hansman, G.S, Biertumpfel, C, Chen, L, Georgiev, I, McLellan, J.S, Katayama, K, Kwong, P.D.
登録日2010-10-18
公開日2011-05-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability.
J.Virol., 85, 2011
7KHF
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BU of 7khf by Molmil
CryoEM structure of LILRB1 D3D4 domain-inserted antibody MDB1 Fab in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MDB1 Fab heavy chain, ...
著者Xu, K, Kwong, P.D.
登録日2020-10-21
公開日2021-03-31
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
Nature, 592, 2021
7KFK
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BU of 7kfk by Molmil
Crystal structure of LILRB1 D3D4 domain in complex with Plasmodium RIFIN (PF3D7_1373400) V2 domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Leukocyte immunoglobulin-like receptor subfamily B member 1, Rifin, ...
著者Xu, K, Kwong, P.D.
登録日2020-10-14
公開日2021-03-31
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
Nature, 592, 2021
7KJP
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Disulfide Stabilized Norovirus GI.1 VLP Shell Region
分子名称: Capsid protein VP1
著者Gorman, J, Kwong, P.D.
登録日2020-10-26
公開日2020-12-02
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Disulfide stabilization of human norovirus GI.1 virus-like particles focuses immune response toward blockade epitopes.
NPJ Vaccines, 5, 2020
4ZPT
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BU of 4zpt by Molmil
Structure of MERS-Coronavirus Spike Receptor-binding Domain (England1 Strain) in Complex with Vaccine-Elicited Murine Neutralizing Antibody D12 (Crystal Form 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D12 Fab Heavy chain, D12 Fab Light chain, ...
著者Joyce, M.G, Mascola, J.R, Graham, B.S, Kwong, P.D.
登録日2015-05-08
公開日2015-10-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.591 Å)
主引用文献Evaluation of candidate vaccine approaches for MERS-CoV
Nat Commun, 6, 2015
7KC1
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BU of 7kc1 by Molmil
Cryo-EM structure of SRR2899884.46167H+MEDI8852L fab in complex with Victoria HA
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
著者Gorman, J, Kwong, P.D.
登録日2020-10-04
公開日2021-05-12
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses.
Front Immunol, 12, 2021
7JZ4
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BU of 7jz4 by Molmil
Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGD21
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MGD21 heavy chain, MGD21 light chain, ...
著者Xu, K, Kwong, P.D.
登録日2020-09-01
公開日2021-05-26
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.747 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZK
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BU of 7jzk by Molmil
Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_0401300) V2 domain
分子名称: LAIR1 ecotodomain from MGD21 antibody, Rifin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Xu, K, Kwong, P.D.
登録日2020-09-02
公開日2021-05-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.457 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZ1
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Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGC34
分子名称: MGC34 heavy chain, MGC34 light chain
著者Xu, K, Kwong, P.D.
登録日2020-09-01
公開日2021-05-26
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JZI
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BU of 7jzi by Molmil
Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_1040300) V2 domain
分子名称: LAIR1 ectodomain from antibody MGD21, PLATINUM (II) ION, Rifin
著者Xu, K, Kwong, P.D.
登録日2020-09-02
公開日2021-05-26
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.707 Å)
主引用文献Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.
Nat Commun, 12, 2021
7JKS
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BU of 7jks by Molmil
Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2411a in complex with HIV-1 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 core, The heavy chain of antibody 2411a, ...
著者Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R.
登録日2020-07-28
公開日2021-06-09
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth.
Immunity, 54, 2021
7JKT
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BU of 7jkt by Molmil
Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2413a in complex with HIV-1 gp120 core
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core from strain d45-01dG5, ...
著者Zhou, T, Chen, X, Kwong, P.D, Mascola, J.R.
登録日2020-07-28
公開日2021-06-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth.
Immunity, 54, 2021
7KNI
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BU of 7kni by Molmil
Cryo-EM structure of Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 5.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
登録日2020-11-04
公開日2020-12-16
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KNE
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BU of 7kne by Molmil
Cryo-EM structure of single ACE2-bound SARS-CoV-2 trimer spike at pH 5.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
登録日2020-11-04
公開日2020-12-16
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KMB
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ACE2-RBD Focused Refinement Using Symmetry Expansion of Applied C3 for Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 7.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Kwong, P.D, Shapiro, L.
登録日2020-11-02
公開日2020-12-09
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020
7KNH
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BU of 7knh by Molmil
Cryo-EM Structure of Double ACE2-Bound SARS-CoV-2 Trimer Spike at pH 5.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Gorman, J, Rapp, M, Kwong, P.D, Shapiro, L.
登録日2020-11-04
公開日2020-12-16
最終更新日2021-12-15
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains.
Cell Host Microbe, 28, 2020

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