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PDB: 104 件

7T9R
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Crystal structure of Crocodile defensin CpoBD13:phosphatidic acid complex
分子名称: (R)-2-(FORMYLOXY)-3-(PHOSPHONOOXY)PROPYL PENTANOATE, 1,2-ETHANEDIOL, CpoBD13, ...
著者Kvansakul, M, Williams, S, Hulett, M.D.
登録日2021-12-19
公開日2023-01-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption.
Nat Commun, 14, 2023
7T9Q
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Crystal structure of Crocodile defensin CpoBD13
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, CpoBD13
著者Kvansakul, M, Williams, S, Hulett, M.D.
登録日2021-12-19
公開日2023-01-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption.
Nat Commun, 14, 2023
1O91
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Crystal Structure of a Collagen VIII NC1 Domain Trimer
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, COLLAGEN ALPHA 1(VIII) CHAIN, SULFATE ION
著者Kvansakul, M, Bogin, O, Hohenester, E, Yayon, A.
登録日2002-12-10
公開日2003-11-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Collagen Alpha1(Viii) Nc1 Trimer.
Matrix Biol., 22, 2003
5KK4
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Crystal Structure of the Plant Defensin NsD7 bound to Phosphatidic Acid
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 1,2-ETHANEDIOL, ACETATE ION, ...
著者Kvansakul, M, Hulett, M.D, Lay, F.T.
登録日2016-06-21
公開日2016-10-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization.
Proc.Natl.Acad.Sci.USA, 113, 2016
1UX6
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Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats
分子名称: CALCIUM ION, THROMBOSPONDIN-1
著者Kvansakul, M, Adams, J.C, Hohenester, E.
登録日2004-02-19
公開日2004-03-18
最終更新日2017-07-12
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of a Thrombospondin C-Terminal Fragment Reveals a Novel Calcium Core in the Type 3 Repeats
Embo J., 23, 2004
1GL4
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Nidogen-1 G2/Perlecan IG3 Complex
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN CORE PROTEIN, NIDOGEN-1, ...
著者Kvansakul, M, Hopf, M, Ries, A, Timpl, R, Hohenester, E.
登録日2001-08-23
公開日2001-11-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the High-Affinity Interaction of Nidogen-1 with Immunoglobulin-Like Domain 3 of Perlecan
Embo J., 20, 2001
2XPX
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Crystal structure of BHRF1:Bak BH3 complex
分子名称: 1,2-ETHANEDIOL, APOPTOSIS REGULATOR BHRF1, BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, ...
著者Kvansakul, M, Huang, D.C.S, Colman, P.M.
登録日2010-08-31
公開日2011-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus Bhrf1.
Plos Pathog., 6, 2010
2JBX
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Crystal Structure of the myxoma virus anti-apoptotic protein M11L
分子名称: M11L PROTEIN
著者Kvansakul, M, Van Delft, M.F, Lee, E.F, Gulbis, J.M, Fairlie, W.D, Huang, D.C.S, Colman, P.M.
登録日2006-12-14
公開日2007-03-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献A Structural Viral Mimic of Prosurvival Bcl-2: A Pivotal Role for Sequestering Proapoptotic Bax and Bak.
Mol.Cell, 25, 2007
2JBY
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A viral protein unexpectedly mimics the structure and function of pro- survival Bcl-2
分子名称: BCL-2 HOMOLOGOUS ANTAGONIST/KILLER 2, M11L PROTEIN, SODIUM ION
著者Kvansakul, M, Van Delft, M.F, Lee, E.F, Gulbis, J.M, Fairlie, W.D, Huang, D.C.S, Colman, P.M.
登録日2006-12-14
公開日2007-03-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.
Mol. Cell, 25, 2007
5AEA
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Crystal structure of human NCAM domain 1
分子名称: CITRATE ANION, NEURAL CELL ADHESION MOLECULE 1
著者Kvansakul, M, Griffiths, K, Foley, M.
登録日2015-08-27
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献I-Bodies, Human Single Domain Antibodies that Antagonize Chemokine Receptor Cxcr4.
J.Biol.Chem., 291, 2016
5AJK
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Crystal structure of variola virus virulence factor F1L in complex with human Bak BH3 domain
分子名称: ACETATE ION, BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, CHLORIDE ION, ...
著者Kvansakul, M, Colman, P.M.
登録日2015-02-25
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Variola Virus F1L is a Bcl-2-Like Protein that Unlike its Vaccinia Virus Counterpart Inhibits Apoptosis Independent of Bim.
Cell Death Dis., 6, 2015
2V6Q
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Crystal Structure of a BHRF-1 : Bim BH3 complex
分子名称: BCL-2-LIKE PROTEIN 11, BHRF1 PROTEIN, BROMIDE ION
著者Kvansakul, M, Huang, D.C.S, Colman, P.M.
登録日2007-07-20
公開日2008-08-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus Bhrf1.
Plos Pathog., 6, 2010
5AJJ
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Crystal structure of variola virus virulence factor F1L in complex with human Bid BH3 domain
分子名称: ACETATE ION, BH3-INTERACTING DOMAIN DEATH AGONIST, GLYCEROL, ...
著者Kvansakul, M, Colman, P.M.
登録日2015-02-25
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Variola Virus F1L is a Bcl-2-Like Protein that Unlike its Vaccinia Virus Counterpart Inhibits Apoptosis Independent of Bim.
Cell Death Dis., 6, 2015
2VTY
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Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain swapped dimer
分子名称: PROTEIN F1
著者Kvansakul, M, Yang, H, Fairlie, W.D, Czabotar, P.E, Fischer, S.F, Perugini, M.A, Huang, D.C.S, Colman, P.M.
登録日2008-05-19
公開日2008-06-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Vaccinia Virus Anti-Apoptotic F1L is a Novel Bcl-2-Like Domain-Swapped Dimer that Binds a Highly Selective Subset of Bh3-Containing Death Ligands.
Cell Death Differ., 15, 2008
2WH6
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Crystal structure of anti-apoptotic BHRF1 in complex with the Bim BH3 domain
分子名称: BCL-2-LIKE PROTEIN 11, BROMIDE ION, EARLY ANTIGEN PROTEIN R, ...
著者Kvansakul, M, Huang, D.C.S, Colman, P.M.
登録日2009-05-01
公開日2010-05-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1.
PLoS Pathog., 6, 2010
4D2M
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Vaccinia Virus F1L bound to Bim BH3
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, BCL-2-LIKE PROTEIN 11, CHLORIDE ION, ...
著者Kvansakul, M, Colman, P.M.
登録日2014-05-12
公開日2014-06-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Insight Into Bh3-Domain Binding of Vaccinia Virus Anti-Apoptotic F1L.
J.Virol., 88, 2014
4D2L
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Vaccinia Virus F1L bound to Bak BH3
分子名称: BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, PROTEIN F1L
著者Kvansakul, M, Colman, P.M.
登録日2014-05-12
公開日2014-06-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.903 Å)
主引用文献Structural Insight Into Bh3-Domain Binding of Vaccinia Virus Anti-Apoptotic F1L.
J.Virol., 88, 2014
6WH0
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Crystal structure of HyBcl-2-4 with HyBax BH3
分子名称: Apoptosis regulator BAX, Maltodextrin-binding protein,Bcl-2-like 4, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Kvansakul, M, Hinds, M.G, Banjara, S.
登録日2020-04-07
公開日2021-03-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The structural basis of Bcl-2 mediated cell death regulation in hydra.
Biochem.J., 477, 2020
6WGZ
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Crystal structure of HyBcl-2-4 with HyBak1 BH3
分子名称: ACETATE ION, Bak, Bcl-2-like 4, ...
著者Kvansakul, M, Hinds, M.G, Banjara, S.
登録日2020-04-07
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of HyBcl-2-4 with HyBak1 BH3 and HyBax BH3
To Be Published
7QTX
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Kaposi sarcoma associated herpes virus (KSHV) encoded apoptosis inhibitor, KsBcl-2 in complex with Puma BH3
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, Bcl-2, ...
著者Suraweera, C.D, Hinds, M.G, Kvansakul, M.
登録日2022-01-17
公開日2022-11-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.11598849 Å)
主引用文献Structural Insight into KsBcl-2 Mediated Apoptosis Inhibition by Kaposi Sarcoma Associated Herpes Virus.
Viruses, 14, 2022
7QTW
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Kaposi sarcoma associated herpes virus(KSHV) encoded apoptosis inhibitor, KsBcl-2 in complex with Bid BH3
分子名称: 1,2-ETHANEDIOL, BH3-interacting domain death agonist p15, Bcl-2
著者Suraweera, C.D, Hinds, M.G, Kvansakul, M.
登録日2022-01-17
公開日2022-11-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structural Insight into KsBcl-2 Mediated Apoptosis Inhibition by Kaposi Sarcoma Associated Herpes Virus.
Viruses, 14, 2022
1GR3
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Structure of the human collagen X NC1 trimer
分子名称: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, COLLAGEN X, ...
著者Bogin, O, Kvansakul, M, Rom, E, Singer, J, Yayon, A, Hohenester, E.
登録日2001-12-12
公開日2002-02-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insight Into Schmid Metaphyseal Chondrodysplasia from the Crystal Structure of the Collagen X Nc1 Domain Trimer.
Structure, 10, 2002
6TZC
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Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin
分子名称: Apoptosis regulator Bcl-2 homolog, Beclin-1, Maltose/maltodextrin-binding periplasmic protein, ...
著者Banjara, S, Kvansakul, M, Hinds, M.G.
登録日2019-08-12
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin.
Viruses, 11, 2019
8QUS
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Crystal structure of the Plasmodium vivax Apical membrane antigen (AMA1) in complex with single domain i-body WD34
分子名称: Apical merozoite antigen 1, single domain i-body WD34
著者Maddumage, J.C, Kvansakul, M.
登録日2023-10-17
公開日2024-07-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A broadly cross-reactive i-body to AMA1 potently inhibits blood and liver stages of Plasmodium parasites.
Nat Commun, 15, 2024
8QU7
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Crystal structure of the Plasmodium falciparum Apical membrane antigen (AMA1) in complex with single domain i-body WD34
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Apical membrane antigen 1, ...
著者Maddumage, J.C, Kvansakul, M.
登録日2023-10-14
公開日2024-07-03
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A broadly cross-reactive i-body to AMA1 potently inhibits blood and liver stages of Plasmodium parasites.
Nat Commun, 15, 2024

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