6WOV
| Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 wild type in complex with FKBP12.6 | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | Authors: | Iyer, K.A, Hu, Y, Nayak, A.R, Kurebayashi, N, Murayama, T, Samso, M. | Deposit date: | 2020-04-25 | Release date: | 2020-08-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
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6WOU
| Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with FKBP12.6 in nanodisc | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | Authors: | Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M. | Deposit date: | 2020-04-25 | Release date: | 2020-08-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
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6WOT
| Cryo-EM structure of recombinant rabbit Ryanodine Receptor type 1 mutant R164C in complex with FKBP12.6 | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION | Authors: | Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M. | Deposit date: | 2020-04-25 | Release date: | 2020-08-05 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
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7VMS
| Structure of recombinant RyR2 mutant K4593A (Ca2+ dataset) | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | Deposit date: | 2021-10-09 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations Nat Commun, 13, 2022
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7VML
| Structure of recombinant RyR2 (EGTA dataset, class 1&2, closed state) | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | Deposit date: | 2021-10-09 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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7VMO
| Structure of recombinant RyR2 (Ca2+ dataset, class 1, open state) | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | Deposit date: | 2021-10-09 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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7VMM
| Structure of recombinant RyR2 (EGTA dataset, class 1, closed state) | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | Deposit date: | 2021-10-09 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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7VMN
| Structure of recombinant RyR2 (EGTA dataset, class 2, closed state) | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | Deposit date: | 2021-10-09 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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7VMQ
| Structure of recombinant RyR2 (Ca2+ dataset, class 3, open state) | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | Deposit date: | 2021-10-09 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations Nat Commun, 13, 2022
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7VMR
| Structure of recombinant RyR2 mutant K4593A (EGTA dataset) | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | Deposit date: | 2021-10-09 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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7VMP
| Structure of recombinant RyR2 (Ca2+ dataset, class 2, open state) | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | Authors: | Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H. | Deposit date: | 2021-10-09 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations. Nat Commun, 13, 2022
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