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PDB: 80 件

3QLU
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Crystal structure of the GluK2/GluK5 (GluR6/KA2) ATD dimer assembly
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
著者Kumar, J, Mayer, M.L.
登録日2011-02-03
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献Structure and assembly mechanism for heteromeric kainate receptors.
Neuron, 71, 2011
1ZBV
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Crystal Structure of the goat signalling protein (SPG-40) complexed with a designed peptide Trp-Pro-Trp at 3.2A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3 like protein 1, WPW
著者Kumar, J, Ethayathulla, A.S, Srivastava, D.B, Singh, N, Sharma, S, Somvanshi, R.K, Dey, S, Singh, T.P.
登録日2005-04-09
公開日2005-04-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Crystal Structure of the goat signalling protein (SPG-40) complexed with a designed peptide Trp-Pro-Trp at 3.2A resolution
to be published
1ZBW
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Crystal structure of the complex formed between signalling protein from goat mammary gland (SPG-40) and a tripeptide Trp-Pro-Trp at 2.8A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3 like protein 1, WPW
著者Kumar, J, Ethayathulla, A.S, Srivastava, D.B, Singh, N, Sharma, S, Somvanshi, R.K, Dey, S, Singh, T.P.
登録日2005-04-09
公開日2005-04-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the complex formed between signalling protein from goat mammary gland (SPG-40) and a tripeptide Trp-Pro-Trp at 2.8A resolution
to be published
7S3L
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Structure of Bacillus subtilis CcrZ (previously called YtmP)
分子名称: Aminoglycoside phosphotransferase family protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Nandakumar, J, Wozniak, K.J.
登録日2021-09-07
公開日2022-05-11
最終更新日2022-06-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and kinase activity of bacterial cell cycle regulator CcrZ.
Plos Genet., 18, 2022
5I2Y
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Crystal Structure of TPP1 K170A
分子名称: Adrenocortical dysplasia protein homolog
著者Nandakumar, J, Smith, E.M.
登録日2016-02-09
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional consequences of a disease mutation in the telomere protein TPP1.
Proc.Natl.Acad.Sci.USA, 113, 2016
5I2X
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Crystal Structure of TPP1 K170del
分子名称: Adrenocortical dysplasia protein homolog
著者Nandakumar, J, Smith, E.
登録日2016-02-09
公開日2016-11-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional consequences of a disease mutation in the telomere protein TPP1.
Proc.Natl.Acad.Sci.USA, 113, 2016
8U8M
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X-ray crystal structure of TEBP-1 MCD2 homodimer
分子名称: COBALT (II) ION, Double-strand telomeric DNA-binding proteins 1
著者Nandakumar, J, Padmanaban, S.
登録日2023-09-18
公開日2024-04-03
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U8L
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X-ray crystal structure of TEBP-2 MCD3 with ds DNA
分子名称: CESIUM ION, DNA (5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*GP*CP*CP*TP*AP*AP*GP*CP*CP*TP*AP*AP*CP*A)-3'), ...
著者Nandakumar, J, Padmanaban, S.
登録日2023-09-18
公開日2024-04-03
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Caenorhabditis elegans telomere-binding proteins TEBP-1 and TEBP-2 adapt the Myb module to dimerize and bind telomeric DNA.
Proc.Natl.Acad.Sci.USA, 121, 2024
7LDG
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Crystal structure of the MEILB2-BRCA2 complex
分子名称: Breast cancer type 2 susceptibility protein, Heat shock factor 2-binding protein
著者Nandakumar, J, Pendlebury, D.F.
登録日2021-01-13
公開日2021-08-11
最終更新日2021-08-25
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structure of a meiosis-specific complex central to BRCA2 localization at recombination sites.
Nat.Struct.Mol.Biol., 28, 2021
8SH1
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Structure of human POT1 DNA binding domain bound to a 5'-phosphorylated junction of a telomeric double-stranded DNA duplex with a 3'-overhang
分子名称: DNA (5'-D(*CP*GP*CP*GP*CP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*AP*CP*GP*CP*GP*CP*G)-3'), Protection of telomeres protein 1
著者Nandakumar, J, Tesmer, V.M.
登録日2023-04-13
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.
Science, 381, 2023
8SH0
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Structure of human POT1 DNA binding domain bound to a 5'-phosphorylated junction of a telomeric DNA hairpin with a 3'-overhang
分子名称: ACETATE ION, DNA (5'-D(P*CP*CP*AP*GP*CP*AP*GP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), Protection of telomeres protein 1
著者Nandakumar, J, Tesmer, V.M.
登録日2023-04-13
公開日2023-08-30
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.
Science, 381, 2023
3KJP
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Crystal Structure of hPOT1V2-GGTTAGGGTTAG
分子名称: 5'-D(*G*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3', Protection of telomeres protein 1
著者Nandakumar, J, Cech, T.R, Podell, E.R.
登録日2009-11-03
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KJO
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Crystal Structure of hPOT1V2-dTrUd(AGGGTTAG)
分子名称: DNA/RNA (5'-D(*T)-R(P*U)-D(P*AP*GP*GP*GP*TP*TP*AP*G)-3'), Protection of telomeres protein 1
著者Nandakumar, J, Cech, T.R, Podell, E.R.
登録日2009-11-03
公開日2010-01-19
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献How telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
2HVQ
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Structure of Adenylated full-length T4 RNA Ligase 2
分子名称: Hypothetical 37.6 kDa protein in Gp24-hoc intergenic region, MAGNESIUM ION
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
2HVS
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Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 2'-deoxyribonucleotide at the nick
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3', 5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3', ...
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
2HVR
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Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 3'-deoxyribonucleotide at the nick
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*AP*TP*TP*CP*CP*GP*AP*TP*AP*GP*TP*GP*GP*GP*GP*TP*CP*GP*CP*AP*AP*TP*TP*G)-3', 5'-D(*CP*AP*AP*TP*TP*GP*CP*GP*AP*C)-R(P*(OMC)P*C)-3', ...
著者Nandakumar, J, Lima, C.D.
登録日2006-07-30
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献RNA Ligase Structures Reveal the Basis for RNA Specificity and Conformational Changes that Drive Ligation Forward.
Cell(Cambridge,Mass.), 127, 2006
5WIR
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Structure of the TRF1-TERB1 interface
分子名称: TERB1-TBM, Telomeric repeat-binding factor 1
著者Nandakumar, J, Pendlebury, D.F, Smith, E.M, Tesmer, V.M.
登録日2017-07-20
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dissecting the telomere-inner nuclear membrane interface formed in meiosis.
Nat. Struct. Mol. Biol., 24, 2017
4UQ6
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Electron density map of GluA2em in complex with LY451646 and glutamate
分子名称: GLUTAMATE RECEPTOR 2, GLUTAMIC ACID
著者Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
登録日2014-06-20
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (12.8 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQQ
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Electron density map of GluK2 desensitized state in complex with 2S,4R-4-methylglutamate
分子名称: GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2, GLUTAMIC ACID
著者Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
登録日2014-06-24
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQJ
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Cryo-EM density map of GluA2em in complex with ZK200775
分子名称: GLUTAMATE RECEPTOR 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
著者Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
登録日2014-06-24
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (10.4 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQK
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Electron density map of GluA2em in complex with quisqualate and LY451646
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2
著者Meyerson, J.R, Kumar, J, Chittori, S, Rao, P, Pierson, J, Bartesaghi, A, Mayer, M.L, Subramaniam, S.
登録日2014-06-24
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (16.4 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
2G8Z
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Crystal structure of the ternary complex of signalling protein from sheep (SPS-40) with trimer and designed peptide at 2.5A resolution
分子名称: (TRP)(PRO)(TRP), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, ...
著者Ethayathulla, A.S, Srivastava, D.B, Kumar, J, Somvanshi, R.K, Sharma, S, Singh, T.P.
登録日2006-03-04
公開日2006-04-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the ternary complex of signalling protein from sheep (SPS-40) with trimer and designed peptide at 2.5A resolution
To be Published
7YSV
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GluK1-1a extracellular domain captured in SYM2081 bound desensitized state
分子名称: Glutamate receptor
著者Dhingra, S, Kumar, J.
登録日2022-08-13
公開日2023-08-16
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8.01 Å)
主引用文献Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors
Elife, 2023
7YSJ
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GluK1-1a in nanodisc captured in SYM2081 bound desensitized state
分子名称: Glutamate receptor
著者Dhingra, S, Kumar, J.
登録日2022-08-12
公開日2023-08-16
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors
Elife, 2023
1SQY
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Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Vikram, P, Prem Kumar, R, Singh, N, Kumar, J, Ethayathulla, A.S, Sharma, S, Kaur, P, Singh, T.P.
登録日2004-03-22
公開日2004-04-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of human diferric lactoferrin at 2.5A resolution using crystals grown at pH 6.5.
To be Published

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