Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 85 件
5WFM
DownloadVisualize
BU of 5wfm by Molmil
Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 10e (SRI-30024)
分子名称: 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-[2-(phenylsulfonyl)ethyl]-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein, ...
著者Kumar, G, White, S.W.
登録日2017-07-12
公開日2018-01-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.251 Å)
主引用文献Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
Sci Rep, 7, 2017
5WFW
DownloadVisualize
BU of 5wfw by Molmil
Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 10j (SRI-30026)
分子名称: 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-N-(5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)-5-hydroxy-6-ox o-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein, ...
著者Kumar, G, White, S.W.
登録日2017-07-12
公開日2018-01-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.292 Å)
主引用文献Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
Sci Rep, 7, 2017
5WG9
DownloadVisualize
BU of 5wg9 by Molmil
Crystal structure of the influenza virus PA endonuclease (E119D mutant) in complex with inhibitor 9b (SRI-30101)
分子名称: 2-{(2S)-1-[3-(2-chlorophenyl)propanoyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-N-(2-phenoxyethyl)-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein, ...
著者Kumar, G, White, S.W.
登録日2017-07-13
公開日2018-01-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
Sci Rep, 7, 2017
5W9G
DownloadVisualize
BU of 5w9g by Molmil
Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 9k (SRI-30023)
分子名称: 2-[(2S)-1-{[(2-chlorophenyl)sulfanyl]acetyl}pyrrolidin-2-yl]-5-hydroxy-6-oxo-N-(2-phenoxyethyl)-1,6-dihydropyrimidine-4 -carboxamide, CHLORIDE ION, MANGANESE (II) ION, ...
著者Kumar, G, White, S.
登録日2017-06-23
公開日2017-12-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
Sci Rep, 7, 2017
5W73
DownloadVisualize
BU of 5w73 by Molmil
Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 9f (SRI-29835)
分子名称: 2-{(2S)-1-[(2-chlorophenoxy)acetyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-N-(2-phenoxyethyl)-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein, ...
著者Kumar, G, White, S.
登録日2017-06-19
公開日2018-01-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.202 Å)
主引用文献Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
Sci Rep, 7, 2017
3EWM
DownloadVisualize
BU of 3ewm by Molmil
Crystal structure of an uncharacterized sugar kinase PH1459 from pyrococcus horikoshii
分子名称: Uncharacterized sugar kinase PH1459
著者Kumar, G, Eswaramoorthy, S, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-10-15
公開日2008-11-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an uncharacterized sugar kinase PH1459 from pyrococcus horikoshii
To be Published
5CCY
DownloadVisualize
BU of 5ccy by Molmil
2009 H1N1 PA endonuclease in complex with dTMP
分子名称: MANGANESE (II) ION, Polymerase acidic protein, THYMIDINE-5'-PHOSPHATE
著者Kumar, G, White, S.W.
登録日2015-07-02
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
5CL0
DownloadVisualize
BU of 5cl0 by Molmil
2009 H1N1 PA endonuclease in complex with rUMP
分子名称: MANGANESE (II) ION, Polymerase acidic protein, URIDINE-5'-MONOPHOSPHATE
著者Kumar, G, White, S.W.
登録日2015-07-15
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
5CGV
DownloadVisualize
BU of 5cgv by Molmil
2009 H1N1 PA endonuclease in complex with L-742,001
分子名称: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, GLYCEROL, MANGANESE (II) ION, ...
著者Kumar, G, White, S.W.
登録日2015-07-09
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5D9J
DownloadVisualize
BU of 5d9j by Molmil
2009 H1N1 PA endonuclease mutant F105S in complex with L-742,001
分子名称: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, Polymerase acidic protein
著者Kumar, G, White, S.W.
登録日2015-08-18
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
5D4G
DownloadVisualize
BU of 5d4g by Molmil
2009 H1N1 PA endonuclease mutant F105S in complex with rUMP
分子名称: MANGANESE (II) ION, Polymerase acidic protein, URIDINE-5'-MONOPHOSPHATE
著者Kumar, G, White, S.W.
登録日2015-08-07
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5D8U
DownloadVisualize
BU of 5d8u by Molmil
2009 H1N1 PA endonuclease mutant E119D in complex with L-742,001
分子名称: (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, Polymerase acidic protein
著者Kumar, G, White, S.W.
登録日2015-08-18
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
5D42
DownloadVisualize
BU of 5d42 by Molmil
2009 H1N1 PA endonuclease mutant F105S in complex with dTMP
分子名称: MANGANESE (II) ION, Polymerase acidic protein, THYMIDINE-5'-PHOSPHATE
著者Kumar, G, White, S.W.
登録日2015-08-07
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DEB
DownloadVisualize
BU of 5deb by Molmil
2009 H1N1 PA endonuclease mutant E119D in complex with rUMP
分子名称: MANGANESE (II) ION, Polymerase acidic protein, URIDINE-5'-MONOPHOSPHATE
著者Kumar, G, White, S.W.
登録日2015-08-25
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
5CZN
DownloadVisualize
BU of 5czn by Molmil
2009 H1N1 PA endonuclease mutant E119D
分子名称: MANGANESE (II) ION, Polymerase acidic protein, SULFATE ION
著者Kumar, G, White, S.W.
登録日2015-07-31
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DBS
DownloadVisualize
BU of 5dbs by Molmil
2009 H1N1 PA endonuclease mutant E119D in complex with dTMP
分子名称: MANGANESE (II) ION, Polymerase acidic protein, SULFATE ION, ...
著者Kumar, G, White, S.W.
登録日2015-08-21
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5DES
DownloadVisualize
BU of 5des by Molmil
2009 H1N1 PA endonuclease domain
分子名称: MANGANESE (II) ION, Polymerase acidic protein
著者Kumar, G, White, S.W.
登録日2015-08-25
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
5VP8
DownloadVisualize
BU of 5vp8 by Molmil
I38T mutant of 2009 H1N1 PA Endonuclease
分子名称: 1-[(3R,5S,7R)-1,5,7,9-tetrakis(2-oxopyrrolidin-1-yl)nonan-3-yl]-1,3-dihydro-2H-pyrrol-2-one, MANGANESE (II) ION, Polymerase acidic protein, ...
著者Kumar, G, White, S.W.
登録日2017-05-04
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors.
MBio, 9, 2018
5EGA
DownloadVisualize
BU of 5ega by Molmil
2009 H1N1 PA endonuclease domain in complex with an N-acylhydrazone inhibitor
分子名称: 3,4,5-tris(oxidanyl)-~{N}-[(~{E})-[3,4,5-tris(oxidanyl)phenyl]methylideneamino]benzamide, MANGANESE (II) ION, Polymerase acidic protein
著者Kumar, G, White, S.W.
登録日2015-10-26
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes.
Sci Rep, 6, 2016
5VPT
DownloadVisualize
BU of 5vpt by Molmil
2009 H1N1 PA Endonuclease in complex with RO-7
分子名称: 1-[(11S)-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-5-hydroxy-3-[(2R)-1,1,1-trifluoropropan-2-yl]-2,3-dihydro-1H-pyrido[2,1-f][1,2,4]triazine-4,6-dione, MANGANESE (II) ION, Polymerase acidic protein, ...
著者Kumar, G, White, S.W.
登録日2017-05-05
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors.
MBio, 9, 2018
5D2O
DownloadVisualize
BU of 5d2o by Molmil
2009 H1N1 PA endonuclease mutant F105S
分子名称: MANGANESE (II) ION, Polymerase acidic protein
著者Kumar, G, White, S.W.
登録日2015-08-05
公開日2016-03-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
5WE7
DownloadVisualize
BU of 5we7 by Molmil
Crystal structure of the influenza virus PA endonuclease in complex with an inhibitor - SRI-29782
分子名称: 2-{(2R)-1-[2-(4-chlorophenoxy)-2-methylpropanoyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid, D-MALATE, MANGANESE (II) ION, ...
著者Kumar, G, White, S.W.
登録日2017-07-07
公開日2018-01-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Crystal structure of the influenza virus PA endonuclease in complex with an inhibitor - SRI-29782
To Be Published
5WCS
DownloadVisualize
BU of 5wcs by Molmil
Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 6b (SRI-29789)
分子名称: 5-hydroxy-2-[(2S)-1-{[(naphthalen-1-yl)oxy]acetyl}pyrrolidin-2-yl]-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein
著者Kumar, G, White, S.W.
登録日2017-07-01
公開日2018-01-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.525 Å)
主引用文献Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
Sci Rep, 7, 2017
5VRJ
DownloadVisualize
BU of 5vrj by Molmil
2009 H1N1 PA Endonuclease in complex with RO-7 and Magnesium
分子名称: 1-[(11S)-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-5-hydroxy-3-[(2R)-1,1,1-trifluoropropan-2-yl]-2,3-dihydro-1H-pyrido[2,1-f][1,2,4]triazine-4,6-dione, MAGNESIUM ION, Polymerase acidic protein, ...
著者Kumar, G, White, S.W.
登録日2017-05-10
公開日2018-04-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors.
MBio, 9, 2018
5WA7
DownloadVisualize
BU of 5wa7 by Molmil
Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 9b (SRI-30101)
分子名称: 2-{(2S)-1-[3-(2-chlorophenyl)propanoyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-N-(2-phenoxyethyl)-1,6-dihydropyrimidine-4-carboxamide, MANGANESE (II) ION, Polymerase acidic protein, ...
著者Kumar, G, White, S.W.
登録日2017-06-25
公開日2018-01-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
Sci Rep, 7, 2017

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon