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PDB: 90 件

1K4R
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Structure of Dengue Virus
分子名称: MAJOR ENVELOPE PROTEIN E
著者Kuhn, R.J, Zhang, W, Rossmann, M.G, Pletnev, S.V, Corver, J, Lenches, E, Jones, C.T, Mukhopadhyay, S, Chipman, P.R, Strauss, E.G, Baker, T.S, Strauss, J.H.
登録日2001-10-08
公開日2002-03-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (24 Å)
主引用文献Structure of dengue virus: implications for flavivirus organization, maturation, and fusion.
Cell(Cambridge,Mass.), 108, 2002
1EGX
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SOLUTION STRUCTURE OF THE ENA-VASP HOMOLOGY 1 (EVH1) DOMAIN OF HUMAN VASODILATOR-STIMULATED PHOSPHOPROTEIN (VASP)
分子名称: VASODILATOR-STIMULATED PHOSPHOPROTEIN
著者Ball, L, Kuhne, R, Hoffmann, B, Hafner, A, Schmieder, P, Volkmer-Engert, R, Hof, M, Wahl, M, Schneider-Mergener, J, Walter, U, Oschkinat, H, Jarchau, T.
登録日2000-02-17
公開日2000-09-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity.
EMBO J., 19, 2000
1R84
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NMR structure of the 13-cis-15-syn retinal in dark_adapted bacteriorhodopsin
分子名称: Bacteriorhodopsin, RETINAL
著者Patzelt, H, Simon, B, Ter Laak, A, Kessler, B, Kuhne, R, Schmieder, P, Oesterhaelt, D, Oschkinat, H.
登録日2003-10-23
公開日2003-11-11
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献The structures of the active center in dark-adapted bacteriorhodopsin by solution-state NMR spectroscopy
Proc.Natl.Acad.Sci.USA, 99, 2002
1S3A
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NMR Solution Structure of Subunit B8 from Human NADH-Ubiquinone Oxidoreductase Complex I (CI-B8)
分子名称: NADH-ubiquinone oxidoreductase B8 subunit
著者Brockmann, C, Diehl, A, Rehbein, K, Kuhne, R, Oschkinat, H.
登録日2004-01-13
公開日2005-01-25
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献The oxidized subunit B8 from human complex I adopts a thioredoxin fold.
Structure, 12, 2004
1JMQ
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YAP65 (L30K mutant) WW domain in Complex with GTPPPPYTVG peptide
分子名称: 65 KDA YES-ASSOCIATED PROTEIN, WW Domain Binding Protein-1
著者Pires, J.R, Taha-Nejad, F, Toepert, F, Ast, T, Hoffmuller, U, Schneider-Mergener, J, Kuhne, R, Macias, M.J, Oschkinat, H.
登録日2001-07-19
公開日2001-12-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
J.Mol.Biol., 314, 2001
1K9Q
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YAP65 WW domain complexed to N-(n-octyl)-GPPPY-NH2
分子名称: 65 kDa Yes-associated protein, N-OCTANE, WW domain binding protein-1
著者Pires, J.R, Taha-Nejad, F, Toepert, F, Ast, T, Hoffmuller, U, Schneider-Mergener, J, Kuhne, R, Macias, M.J, Oschkinat, H.
登録日2001-10-30
公開日2001-12-28
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
J.Mol.Biol., 314, 2001
1K9R
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YAP65 WW domain complexed to Acetyl-PLPPY
分子名称: 65 kDa Yes-associated protein, WW domain binding protein-1
著者Pires, J.R, Taha-Nejad, F, Toepert, F, Ast, T, Hoffmuller, U, Schneider-Mergener, J, Kuhne, R, Macias, M.J, Oschkinat, H.
登録日2001-10-30
公開日2001-12-28
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries reveal a minimal binding epitope.
J.Mol.Biol., 314, 2001
1OQA
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Solution structure of the BRCT-c domain from human BRCA1
分子名称: Breast cancer type 1 susceptibility protein
著者Gaiser, O.J, Ball, L.J, Schmieder, P, Leitner, D, Strauss, H, Wahl, M, Kuhne, R, Oschkinat, H, Heinemann, U.
登録日2003-03-07
公開日2004-06-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1.
Biochemistry, 43, 2004
1Q8G
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NMR structure of human Cofilin
分子名称: Cofilin, non-muscle isoform
著者Pope, B.J, Zierler-Gould, K.M, Kuhne, R, Weeds, A.G, Ball, L.J.
登録日2003-08-21
公開日2004-07-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of human cofilin: rationalizing actin binding and pH sensitivity
J.Biol.Chem., 279, 2004
1Q8X
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NMR structure of human cofilin
分子名称: Cofilin, non-muscle isoform
著者Pope, B.J, Zierler-Gould, K.M, Kuhne, R, Weeds, A.G, Ball, L.J.
登録日2003-08-22
公開日2004-07-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of human cofilin: rationalizing actin binding and pH sensitivity
J.Biol.Chem., 279, 2004
1R2N
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NMR structure of the all-trans retinal in dark-adapted Bacteriorhodopsin
分子名称: Bacteriorhodopsin, RETINAL
著者Patzelt, H, Simon, B, terLaak, A, Kessler, B, Kuhne, R, Schmieder, P, Oesterhaelt, D, Oschkinat, H.
登録日2003-09-29
公開日2003-10-28
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献The structures of the active center in dark-adapted bacteriorhodopsin by solution-state NMR spectroscopy
Proc.Natl.Acad.Sci.USA, 99, 2002
1R4T
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Solution structure of exoenzyme S
分子名称: exoenzyme S
著者Langdon, G.M, Leitner, D, Labudde, D, Kuhne, R, Schmieder, P, Aktories, K, Oschkinat, H.O, Schmidt, G.
登録日2003-10-08
公開日2005-04-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal GTPase activating domain of Pseudomonas aeruginosa exoenzyme S
To be Published
1IEZ
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Solution Structure of 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase of Riboflavin Biosynthesis
分子名称: 3,4-Dihydroxy-2-Butanone 4-Phosphate Synthase
著者Kelly, M.J.S, Ball, L.J, Kuhne, R, Bacher, A, Oschkinat, H.
登録日2001-04-11
公開日2001-11-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The NMR structure of the 47-kDa dimeric enzyme 3,4-dihydroxy-2-butanone-4-phosphate synthase and ligand binding studies reveal the location of the active site.
Proc.Natl.Acad.Sci.USA, 98, 2001
1L2Z
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CD2BP2-GYF domain in complex with proline-rich CD2 tail segment peptide
分子名称: CD2 ANTIGEN (CYTOPLASMIC TAIL)-BINDING PROTEIN 2, T-CELL SURFACE ANTIGEN CD2
著者Freund, C, Kuhne, R, Yang, H, Park, S, Reinherz, E.L, Wagner, G.
登録日2002-02-26
公開日2002-11-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules
Embo J., 21, 2002
2JNU
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Solution structure of the RGS domain of human RGS14
分子名称: Regulator of G-protein signaling 14
著者Dowler, E.F, Diehl, A, Bray, J, Elkins, J, Soundararajan, M, Doyle, D.A, Gileadi, C, Phillips, C, Schoch, G.A, Yang, X, Brockmann, C, Leidert, M, Rehbein, K, Schmieder, P, Kuhne, R, Higman, V.A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC)
登録日2007-02-02
公開日2007-02-27
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2R6P
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Fit of E protein and Fab 1A1D-2 into 24 angstrom resolution cryoEM map of Fab complexed with dengue 2 virus.
分子名称: Heavy chain of 1A1D-2, Light chain of 1A1D-2, Major envelope protein E
著者Lok, S.M, Kostyuchenko, V.K, Holdaway, H.A, Chipman, P.R, Kuhn, R.J, Rossmann, M.G.
登録日2007-09-06
公開日2007-12-25
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (24 Å)
主引用文献Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins.
Nat.Struct.Mol.Biol., 15, 2008
8FE4
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Structure of dengue virus (DENV2) in complex with prM13, an anti-PrM monoclonal antibody
分子名称: Envelope protein E, prM protein, prM13 Fab Heavy Chain, ...
著者Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C.
登録日2022-12-05
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FE3
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Structure of dengue virus (DENV2) in complex with prM12, an anti-PrM monoclonal antibody
分子名称: Envelope protein E, prM protein, prM12 Fab Heavy Chain, ...
著者Dowd, A.D, Sirohi, D, Speer, S, Mukherjee, S, Govero, J, Aleshnick, M, Larman, B, Sukupolvi-Petty, S, Sevvana, M, Miller, A.S, Klose, T, Zheng, A, Kielian, M, Kuhn, R.J, Diamond, M.S, Pierson, T.C.
登録日2022-12-05
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (10.2 Å)
主引用文献prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Proc.Natl.Acad.Sci.USA, 120, 2023
4UOM
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Electron Cryo-microscopy of Venezuelan Equine Encephalitis Virus TC- 83 in complex with neutralizing antibody Fab F5
分子名称: FAB FRAGMENT HEAVY CHAIN, FAB FRAGMENT LIGHT CHAIN
著者Porta, J, Jose, J, Roehrig, J.T, Blair, C.D, Kuhn, R.J, Rossmann, M.G.
登録日2014-06-05
公開日2014-10-15
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Locking and Blocking the Viral Landscape of an Alphavirus with Neutralizing Antibodies.
J.Virol., 88, 2014
4UOK
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Electron Cryo-microscopy of Venezuelan Equine Encephalitis Virus TC-83 in complex with neutralizing antibody Fab 3B4C-4
分子名称: FAB FRAGMENT HEAVY CHAIN, FAB FRAGMENT LIGHT CHAIN
著者Porta, J, Jose, J, Roehrig, J.T, Blair, C.D, Kuhn, R.J, Rossmann, M.G.
登録日2014-06-04
公開日2014-09-17
最終更新日2019-05-29
実験手法ELECTRON MICROSCOPY (18 Å)
主引用文献Locking and blocking the viral landscape of an alphavirus with neutralizing antibodies.
J.Virol., 88, 2014
7T17
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Zika Virus asymmetric unit bound with IgM antibody DH1017 Fab fragment
分子名称: Core protein, DH1017.IgM FabC constant domain, DH1017.IgM IgH, ...
著者Miller, A.S, Kuhn, R.J.
登録日2021-12-01
公開日2022-11-23
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (5.26 Å)
主引用文献A Zika virus-specific IgM elicited in pregnancy exhibits ultrapotent neutralization.
Cell, 185, 2022
6W09
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Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
分子名称: E1 glycoprotein, E2 glycoprotein, E3, ...
著者Miller, A.S, Kuhn, R.J.
登録日2020-02-29
公開日2020-08-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6CO8
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Structure of Zika virus at a resolution of 3.1 Angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein
著者Sevvana, M, Long, F, Miller, A.J, Klose, T, Buda, G, Sun, L, Kuhn, R.J, Rossmann, M.R.
登録日2018-03-12
公開日2018-07-04
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Refinement and Analysis of the Mature Zika Virus Cryo-EM Structure at 3.1 angstrom Resolution.
Structure, 26, 2018
6W2U
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Mayaro Virus glycoprotein E1 ectodomain and glycoportien E2 ectodomain asymmetric unit
分子名称: Spike glycoprotein E1, Spike glycoprotein E2
著者Miller, A.S, Kuhn, R.J.
登録日2020-03-08
公開日2020-10-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020
6W1C
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Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain
分子名称: E1 glycoprotein, E2 glycoprotein, Fab CHK-265 heavy chain, ...
著者Miller, A.S, Kuhn, R.J.
登録日2020-03-04
公開日2020-08-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site.
Cell Host Microbe, 28, 2020

 

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