5XFV
| Crystal structures of FMN-bound form of dihydroorotate dehydrogenase from Trypanosoma brucei | 分子名称: | Dihydroorotate dehydrogenase (fumarate), FLAVIN MONONUCLEOTIDE, MALONATE ION | 著者 | Kubota, T, Tani, O, Yamaguchi, T, Namatame, I, Sakashita, H, Furukawa, K, Yamasaki, K. | 登録日 | 2017-04-11 | 公開日 | 2018-04-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase fromTrypanosoma brucei. FEBS Open Bio, 8, 2018
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5XFW
| Crystal structures of FMN-free form of dihydroorotate dehydrogenase from Trypanosoma brucei | 分子名称: | Dihydroorotate dehydrogenase (fumarate), MALONATE ION | 著者 | Kubota, T, Tani, O, Yamaguchi, T, Namatame, I, Sakashita, H, Furukawa, K, Yamasaki, K. | 登録日 | 2017-04-11 | 公開日 | 2018-04-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase fromTrypanosoma brucei. FEBS Open Bio, 8, 2018
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3ASQ
| Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with H-antigen | 分子名称: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | 著者 | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | 登録日 | 2010-12-17 | 公開日 | 2012-01-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the recognition of Lewis antigens by genogroup I norovirus J.Virol., 86, 2012
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3ASR
| Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with Lewis-a | 分子名称: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | 著者 | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | 登録日 | 2010-12-17 | 公開日 | 2012-01-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the recognition of Lewis antigens by genogroup I norovirus J.Virol., 86, 2012
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3ASS
| Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with Lewis-b | 分子名称: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | 著者 | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | 登録日 | 2010-12-17 | 公開日 | 2012-01-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the recognition of Lewis antigens by genogroup I norovirus J.Virol., 86, 2012
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3ASP
| Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with A-antigen | 分子名称: | Capsid protein, SODIUM ION, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)]beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | 登録日 | 2010-12-17 | 公開日 | 2012-01-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis for the recognition of Lewis antigens by genogroup I norovirus J.Virol., 86, 2012
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3AST
| Crystal structure of P domain Q389N mutant from Norovirus Funabashi258 stain in the complex with Lewis-b | 分子名称: | Capsid protein, P-NITROPHENOL, SODIUM ION, ... | 著者 | Kubota, T, Kumagai, A, Itoh, H, Furukawa, S, Narimatsu, H, Wakita, T, Ishii, K, Takeda, N, Someya, Y, Shirato, H. | 登録日 | 2010-12-17 | 公開日 | 2012-01-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural basis for the recognition of Lewis antigens by genogroup I norovirus J.Virol., 86, 2012
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2D7I
| Crystal structure of pp-GalNAc-T10 with UDP, GalNAc and Mn2+ | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kubota, T, Shiba, T, Sugioka, S, Kato, R, Wakatsuki, S, Narimatsu, H. | 登録日 | 2005-11-21 | 公開日 | 2006-11-07 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10) J.Mol.Biol., 359, 2006
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2D7R
| Crystal structure of pp-GalNAc-T10 complexed with GalNAc-Ser on lectin domain | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kubota, T, Shiba, T, Sugioka, S, Kato, R, Wakatsuki, S, Narimatsu, H. | 登録日 | 2005-11-25 | 公開日 | 2006-11-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10) J.Mol.Biol., 359, 2006
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6LFF
| transcription factor SATB1 CUTr1 domain in complex with a phosphorothioate DNA | 分子名称: | DNA (5'-D(*GP*(C7R)P*(PST)P*AP*AP*TP*AP*TP*AP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*TP*(AS)P*(PST)P*(AS)P*(PST)P*TP*AP*GP*C)-3'), DNA-binding protein SATB1 | 著者 | Akutsu, Y, Kubota, T, Yamasaki, T, Yamasaki, K. | 登録日 | 2019-12-02 | 公開日 | 2020-04-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Enhanced affinity of racemic phosphorothioate DNA with transcription factor SATB1 arising from diastereomer-specific hydrogen bonds and hydrophobic contacts. Nucleic Acids Res., 48, 2020
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4LFQ
| High resolution x-ray crystal structure of L-ShK toxin | 分子名称: | Potassium channel toxin ShK | 著者 | Dang, B, Kubota, T, Mandal, K, Bezanilla, F, Kent, S.B.H. | 登録日 | 2013-06-27 | 公開日 | 2013-08-14 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.059 Å) | 主引用文献 | Native Chemical Ligation at Asx-Cys, Glx-Cys: Chemical Synthesis and High-Resolution X-ray Structure of ShK Toxin by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
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4LFS
| High resolution x-ray structure of racemic ShK toxin | 分子名称: | CHLORIDE ION, GLYCEROL, Potassium channel toxin ShK | 著者 | Dang, B, Kubota, T, Mandal, K, Bezanilla, F, Kent, S.B.H. | 登録日 | 2013-06-27 | 公開日 | 2013-08-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Native Chemical Ligation at Asx-Cys, Glx-Cys: Chemical Synthesis and High-Resolution X-ray Structure of ShK Toxin by Racemic Protein Crystallography. J.Am.Chem.Soc., 135, 2013
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7F4C
| The crystal structure of the immature holo-enzyme of homoserine dehydrogenase complexed with NADP and 1,4-butandiol from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | 分子名称: | 1,4-BUTANEDIOL, Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Ogata, K, Kaneko, R, Kubota, T, Watanabe, K, Kurihara, E, Oshima, T, Yoshimune, K, Goto, M. | 登録日 | 2021-06-18 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase. Commun Biol, 5, 2022
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7F4B
| The crystal structure of the immature apo-enzyme of homoserine dehydrogenase from the hyperthermophilic archaeon Sulfurisphaera tokodaii. | 分子名称: | MAGNESIUM ION, homoserine dehydrogenase | 著者 | Kurihara, E, Kubota, T, Watanabe, K, Ogata, K, Kaneko, R, Oshima, T, Yoshimune, K, Goto, M. | 登録日 | 2021-06-18 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Conformational changes in the catalytic region are responsible for heat-induced activation of hyperthermophilic homoserine dehydrogenase. Commun Biol, 5, 2022
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5I5C
| X-ray crystal structure of allo-Thr31-ShK | 分子名称: | GLYCEROL, Kappa-stichotoxin-She3a, LITHIUM ION, ... | 著者 | Dang, B, Kubota, T, Manda, K.l, Shen, R, Bezanilla, F, Roux, B, Kent, S.B.H. | 登録日 | 2016-02-15 | 公開日 | 2017-01-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angew. Chem. Int. Ed. Engl., 56, 2017
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5I5B
| quasi racemic structure of allo-Thr13-ShK and D-ShK | 分子名称: | D-ShK, GLYCEROL, Kappa-stichotoxin-She3a, ... | 著者 | Dang, B, Kubota, T, Mandal, K, Shen, R, Bezanilla, F, Roux, B, Kent, S.B.H. | 登録日 | 2016-02-15 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angew. Chem. Int. Ed. Engl., 56, 2017
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5I5A
| quasi racemic structure of allo-Ile7-ShK and D-ShK | 分子名称: | D-MALATE, D-ShK, GLYCEROL, ... | 著者 | Dang, B, Kubota, T, Mandal, K, Shen, R, Bezanilla, F, Roux, B, Kent, S.B.H. | 登録日 | 2016-02-14 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Inversion of the Side-Chain Stereochemistry of Indvidual Thr or Ile Residues in a Protein Molecule: Impact on the Folding, Stability, and Structure of the ShK Toxin. Angew. Chem. Int. Ed. Engl., 56, 2017
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7VU9
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5CY0
| Total Chemical Synthesis, Covalent Structure Verification, and X-ray Structure of Bioactive Ts3 Toxin by Racemic Protein Crystallography | 分子名称: | GLYCEROL, Ts3 Toxin | 著者 | Dang, B, Kubota, T, Mandal, K, Correa, A.M, Bezanilla, F, Kent, S.B. | 登録日 | 2015-07-29 | 公開日 | 2016-06-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Elucidation of the Covalent and Tertiary Structures of Biologically Active Ts3 Toxin. Angew.Chem.Int.Ed.Engl., 55, 2016
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7V92
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7V91
| Crystal Structure of the Catalytic Domain of a Family GH19 Chitinase from Gazyumaru, Ficus microcarpa | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Kozome, D, Kubota, T, Ishikawa, K. | 登録日 | 2021-08-24 | 公開日 | 2022-04-27 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Analysis and Construction of a Thermostable Antifungal Chitinase. Appl.Environ.Microbiol., 88, 2022
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6A86
| Pholiota squarrosa lectin | 分子名称: | (3R)-butane-1,3-diol, lectin | 著者 | Yamasaki, K, Yamasaki, T, Kubota, T. | 登録日 | 2018-07-06 | 公開日 | 2019-04-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for specific recognition of core fucosylation in N-glycans by Pholiota squarrosa lectin (PhoSL). Glycobiology, 29, 2019
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6A87
| Pholiota squarrosa lectin (PhoSL) in complex with fucose(alpha1-6)GlcNAc | 分子名称: | METHANETHIOL, alpha-L-fucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yamasaki, K, Yamasaki, T, Kubota, T. | 登録日 | 2018-07-06 | 公開日 | 2019-04-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Structural basis for specific recognition of core fucosylation in N-glycans by Pholiota squarrosa lectin (PhoSL). Glycobiology, 29, 2019
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3WBL
| Crystal structure of CDK2 in complex with pyrazolopyrimidine inhibitor | 分子名称: | ACETATE ION, Cyclin-dependent kinase 2, N~7~-(4-ethoxyphenyl)-6-methyl-N~5~-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine | 著者 | Fujino, A, Fukushima, K, Kubota, T, Kosugi, T, Takimoto-Kamimura, M. | 登録日 | 2013-05-20 | 公開日 | 2013-10-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of human cyclin-dependent kinase-2 complex with MK2 inhibitor TEI-I01800: insight into the selectivity. J.SYNCHROTRON RADIAT., 20, 2013
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3WI6
| Crystal structure of MAPKAP Kinase-2 (MK2) in complex with non-selective inhibitor | 分子名称: | MAP kinase-activated protein kinase 2, N-[(3S)-piperidin-3-yl]-7,8-dihydro-6H-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidin-5-amine | 著者 | Fujino, A, Fukushima, K, Kubota, T, Matsumoto, Y, Takimoto-Kamimura, M. | 登録日 | 2013-09-06 | 公開日 | 2013-12-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Structure of the beta-form of human MK2 in complex with the non-selective kinase inhibitor TEI-L03090 Acta Crystallogr.,Sect.F, 69, 2013
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