Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 50 results
4WHY
DownloadVisualize
BU of 4why by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P21 crystal form
Descriptor: Heavy chain of Fab fragment derived from neutralizing antibody 3/11, Light chain of Fab fragment derived from neutralizing antibody 3/11, epitope peptide
Authors:Krey, T, Rey, F.A.
Deposit date:2014-09-24
Release date:2014-12-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein e2 recognized by broadly neutralizing antibodies.
J.Virol., 89, 2015
4WHT
DownloadVisualize
BU of 4wht by Molmil
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P1 crystal form
Descriptor: Epitope peptide, Heavy chain of the Fab fragment derived from neutralizing antibody 3/11, Light chain of the Fab fragment derived from neutralizing antibody 3/11
Authors:Krey, T, Rey, F.A.
Deposit date:2014-09-23
Release date:2014-12-17
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural flexibility of a conserved antigenic region in hepatitis C virus glycoprotein e2 recognized by broadly neutralizing antibodies.
J.Virol., 89, 2015
4OJE
DownloadVisualize
BU of 4oje by Molmil
Crystal structure of a C-terminally truncated trimeric ectodomain of the C. elegans fusion protein EFF-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EFF-1A, ...
Authors:Krey, T, Rey, F.A.
Deposit date:2014-01-21
Release date:2014-05-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural basis of eukaryotic cell-cell fusion
Cell(Cambridge,Mass.), 157, 2014
4OJD
DownloadVisualize
BU of 4ojd by Molmil
Crystal structure of a C-terminally truncated trimeric ectodomain of the C. elegans fusion protein EFF-1 G260A/D321E/D322E mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, EFF-1A, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Krey, T, Rey, F.A.
Deposit date:2014-01-21
Release date:2014-05-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural basis of eukaryotic cell-cell fusion
Cell(Cambridge,Mass.), 157, 2014
4JVP
DownloadVisualize
BU of 4jvp by Molmil
Three dimensional structure of broadly neutralizing anti - Hepatitis C virus (HCV) glycoprotein E2 alpaca nanobody D03
Descriptor: Anti-HCV E2 alpaca nanobody D03, SULFATE ION
Authors:Krey, T, Rey, F.A.
Deposit date:2013-03-26
Release date:2013-04-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission.
Hepatology, 58, 2013
4JZO
DownloadVisualize
BU of 4jzo by Molmil
Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-27
Descriptor: Anti-HCV E2 Fab HC84-27 heavy chain, Anti-HCV E2 Fab HC84-27 light chain, Envelope glycoprotein E2
Authors:Krey, T, Rey, F.A.
Deposit date:2013-04-03
Release date:2013-06-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.
Plos Pathog., 9, 2013
4JZN
DownloadVisualize
BU of 4jzn by Molmil
Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC84-1
Descriptor: Anti-HCV E2 Fab HC84-1 heavy chain, Anti-HCV E2 Fab HC84-1 light chain, Envelope glycoprotein E2, ...
Authors:Krey, T, Rey, F.A.
Deposit date:2013-04-03
Release date:2013-06-05
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis of HCV neutralization by human monoclonal antibodies resistant to viral neutralization escape.
Plos Pathog., 9, 2013
4OJC
DownloadVisualize
BU of 4ojc by Molmil
Crystal structure of the wild-type full-length trimeric ectodomain of the C. elegans fusion protein EFF-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EFF-1A, ...
Authors:Krey, T, Rey, F.A.
Deposit date:2014-01-21
Release date:2014-05-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Structural basis of eukaryotic cell-cell fusion
Cell(Cambridge,Mass.), 157, 2014
4DW4
DownloadVisualize
BU of 4dw4 by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 5'-UMP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DWC
DownloadVisualize
BU of 4dwc by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with Zn ions
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DW3
DownloadVisualize
BU of 4dw3 by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 5'-CMP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CYTIDINE-5'-MONOPHOSPHATE, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DWA
DownloadVisualize
BU of 4dwa by Molmil
Crystal structure of an active-site mutant of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a CpUpC trinucleotide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DVK
DownloadVisualize
BU of 4dvk by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 strain NCP-7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-23
Release date:2012-05-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DW7
DownloadVisualize
BU of 4dw7 by Molmil
Crystal structure of an active-site mutant of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a CpU dinucleotide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-R(*CP*U)-3', ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DVN
DownloadVisualize
BU of 4dvn by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 2'-UMP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-23
Release date:2012-05-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DW5
DownloadVisualize
BU of 4dw5 by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with a non-cleavable CpU dinucleotide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-24
Release date:2012-05-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
4DVL
DownloadVisualize
BU of 4dvl by Molmil
Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 in complex with 2'-3'-cyclo-UMP
Descriptor: 1-[(2S,3aS,4S,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-2-oxidotetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]pyrimidine-2,4( 1H,3H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A.
Deposit date:2012-02-23
Release date:2012-05-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity.
Structure, 20, 2012
8QP6
DownloadVisualize
BU of 8qp6 by Molmil
Crystal structure of Hepatitis C Virus E1 glycoprotein epitope 314-324 scaffold design 1W4K_08 in complex with neutralizing antibody F(ab) fragment IGH526
Descriptor: 1W4K_08, F(ab) IGH526
Authors:Nagarathinam, K, Krey, T.
Deposit date:2023-09-30
Release date:2024-10-09
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Crystal structure of Hepatitis C Virus E1 glycoprotein epitope 314-324 scaffold design 1W4K_08 in complex with neutralizing antibody F(ab) fragment IGH526
To Be Published
8QP7
DownloadVisualize
BU of 8qp7 by Molmil
Crystal structure of Hepatitis C Virus E2 glycoprotein epitopeI 411-424 scaffold design 4CIL_04
Descriptor: Yop effector YopM,Internalin B
Authors:Nagarathinam, K, Cramer, J.T, Krey, T.
Deposit date:2023-09-30
Release date:2024-10-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of Hepatitis C Virus E2 glycoprotein epitopeI 411-424 scaffold design 4CIL_04
To Be Published
6S3D
DownloadVisualize
BU of 6s3d by Molmil
Structure of D25 Fab in complex with scaffold S0_2.126
Descriptor: Heavy Chain, Light Chain, S0_2.126
Authors:Cramer, J.T, Krey, T.
Deposit date:2019-06-25
Release date:2020-04-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:De novo protein design enables the precise induction of RSV-neutralizing antibodies.
Science, 368, 2020
5OW3
DownloadVisualize
BU of 5ow3 by Molmil
Crystal structure of a C-terminally truncated trimeric ectodomain of the Arabidopsis thaliana gamete fusion protein HAP2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, GLYCEROL, ...
Authors:Fedry, J, Legrand, P, Rey, F.A, Krey, T.
Deposit date:2017-08-30
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes.
PLoS Biol., 16, 2018
5OW4
DownloadVisualize
BU of 5ow4 by Molmil
Crystal structure of a protease-resistant fragment of the Trypanosoma cruzi gamete fusion protein HAP2 ectodomain
Descriptor: Uncharacterized protein
Authors:Fedry, J, Rey, F.A, Krey, T.
Deposit date:2017-08-30
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes.
PLoS Biol., 16, 2018
8RRN
DownloadVisualize
BU of 8rrn by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with pT1616 Fab
Descriptor: Spike protein S1, pT1616 Fab heavy chain, pT1616 Fab light chain
Authors:Hansen, G, Krey, T.
Deposit date:2024-01-23
Release date:2024-10-30
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:A human monoclonal antibody neutralizing SARS-CoV-2 Omicron variants containing the L452R mutation
To be published
3U6R
DownloadVisualize
BU of 3u6r by Molmil
Three dimensional structure of broadly neutralizing anti - Hepatitis C virus (HCV) glycoprotein E2 single chain FV fragment 1:7
Descriptor: Antibody 1:7 (Heavy chain), Antibody 1:7 (Light chain), SULFATE ION
Authors:Gilmartin, A.A, Lamp, B, Ruemenapf, T, Persson, A.A, Rey, F.A, Krey, T.
Deposit date:2011-10-12
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cells.
Protein Eng.Des.Sel., 25, 2012
8PHI
DownloadVisualize
BU of 8phi by Molmil
Crystal structure of prefusion-stabilized RSV F Variant DS-Cav1 in complex with Lonafarnib
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, 4-{2-[4-(3,10-DIBROMO-8-CHLORO-6,11-DIHYDRO-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YL)PIPERIDIN-1-YL]-2-OXOETHYL}PIPERIDINE-1-CARBOXAMIDE, CALCIUM ION, ...
Authors:Rajak, M, Krey, T.
Deposit date:2023-06-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.289 Å)
Cite:Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor.
Nat Commun, 15, 2024

 

12>

226707

數據於2024-10-30公開中

PDB statisticsPDBj update infoContact PDBjnumon