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PDB: 145 件

6SNH
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Cryo-EM structure of yeast ALG6 in complex with 6AG9 Fab and Dol25-P-Glc
分子名称: 6AG9 Fab heavy chain, 6AG9 Fab light chain, Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase, ...
著者Bloch, J.S, Pesciullesi, G, Boilevin, J, Nosol, K, Irobalieva, R.N, Darbre, T, Aebi, M, Kossiakoff, A.A, Reymond, J.L, Locher, K.P.
登録日2019-08-24
公開日2020-03-11
最終更新日2020-04-01
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structure and mechanism of the ER-based glucosyltransferase ALG6.
Nature, 579, 2020
5BK2
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BU of 5bk2 by Molmil
Crystal structure of maltose binding protein in complex with a peristeric synthetic antibody
分子名称: CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ...
著者Mukherjee, S, Kossiakoff, A.A.
登録日2017-09-12
公開日2018-01-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
J. Biol. Chem., 293, 2018
5BK1
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Crystal structure of maltose binding protein in complex with an endosteric synthetic antibody
分子名称: CHLORIDE ION, GLYCEROL, Maltose binding protein, ...
著者Mukherjee, S, Kossiakoff, A.A.
登録日2017-09-12
公開日2018-01-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
J. Biol. Chem., 293, 2018
5BJZ
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BU of 5bjz by Molmil
Crystal structure of maltose binding protein in complex with an allosteric synthetic antibody
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ...
著者Mukherjee, S, Kossiakoff, A.A.
登録日2017-09-12
公開日2018-01-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
J. Biol. Chem., 293, 2018
4XTR
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BU of 4xtr by Molmil
Structure of Get3 bound to the transmembrane domain of Pep12
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ...
著者Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J.
登録日2015-01-23
公開日2015-03-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
4XVU
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BU of 4xvu by Molmil
Structure of Get3 bound to the transmembrane domain of Nyv1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Antibody heavy chain, ...
著者Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J.
登録日2015-01-28
公開日2015-03-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
4XH2
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BU of 4xh2 by Molmil
Crystal structure of human paxillin LD4 motif in complex with Fab fragment
分子名称: ACETATE ION, ACETYL GROUP, Fab Heavy Chain, ...
著者Nocula-Lugowska, M, Lugowski, M, Salgia, R, Kossiakoff, A.A.
登録日2015-01-04
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
J.Mol.Biol., 427, 2015
4XWO
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Structure of Get3 bound to the transmembrane domain of Sec22
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ...
著者Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J.
登録日2015-01-29
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
4XMN
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Structure of the yeast coat nucleoporin complex, space group P212121
分子名称: Antibody 87 heavy chain, Antibody 87 light chain, Nucleoporin NUP120, ...
著者Stuwe, T, Correia, A.R, Lin, D.H, Paduch, M, Lu, V.T, Kossiakoff, A.A, Hoelz, A.
登録日2015-01-14
公開日2015-03-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (7.6 Å)
主引用文献Nuclear pores. Architecture of the nuclear pore complex coat.
Science, 347, 2015
4XMM
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BU of 4xmm by Molmil
Structure of the yeast coat nucleoporin complex, space group C2
分子名称: Antibody 57 heavy chain, Antibody 57 light chain, Nucleoporin NUP120, ...
著者Stuwe, T, Correia, A.R, Lin, D.H, Paduch, M, Lu, V.T, Kossiakoff, A.A, Hoelz, A.
登録日2015-01-14
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (7.384 Å)
主引用文献Nuclear pores. Architecture of the nuclear pore complex coat.
Science, 347, 2015
4XGZ
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BU of 4xgz by Molmil
Crystal structure of human paxillin LD2 motif in complex with Fab fragment
分子名称: 1,2-ETHANEDIOL, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ...
著者Nocula-Lugowska, M, Lugowski, M, Salgia, R, Kossiakoff, A.A.
登録日2015-01-04
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
J.Mol.Biol., 427, 2015
6USF
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BU of 6usf by Molmil
CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor with varenicline in complex with anti-BRIL synthetic antibody BAK5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, ...
著者Alvarez, F.J.D, Mukherjee, S, Han, S, Ammirati, M, Kossiakoff, A.A.
登録日2019-10-26
公開日2020-04-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
6UR8
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BU of 6ur8 by Molmil
CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor in complex with varenicline
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chimera of soluble cytochrome b562 (BRIL) and neuronal acetylcholine receptor subunit alpha-4, Neuronal acetylcholine receptor subunit beta-2, ...
著者Alvarez, F.J.D, Mukherjee, S, Han, S, Ammirati, M, Kossiakoff, A.A.
登録日2019-10-22
公開日2020-04-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.71 Å)
主引用文献Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Nat Commun, 11, 2020
7PTI
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BU of 7pti by Molmil
STRUCTURAL EFFECTS INDUCED BY REMOVAL OF A DISULFIDE BRIDGE. THE X-RAY STRUCTURE OF THE C30A(SLASH)C51A MUTANT OF BASIC PANCREATIC TRYPSIN INHIBITOR AT 1.6 ANGSTROMS
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION
著者Eigenbrot, C, Randal, M, Kossiakoff, A.A.
登録日1990-03-08
公開日1991-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural effects induced by removal of a disulfide-bridge: the X-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 A.
Protein Eng., 3, 1990
2FD7
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BU of 2fd7 by Molmil
X-ray Crystal Structure of Chemically Synthesized Crambin
分子名称: Crambin
著者Bang, D, Tereshko, V, Kossiakoff, A.A, Kent, S.B.
登録日2005-12-13
公開日2007-01-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Role of a salt bridge in the model protein crambin explored by chemical protein synthesis: X-ray structure of a unique protein analogue, [V15A]crambin-alpha-carboxamide.
Mol Biosyst, 5, 2009
2FCQ
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BU of 2fcq by Molmil
X-ray Crystal Structure of a Chemically Synthesized Ubiquitin with a Cubic Space Group
分子名称: CADMIUM ION, Ubiquitin
著者Bang, D, Gribenko, A.V, Tereshko, V, Kossiakoff, A.A, Kent, S.B, Makhatadze, G.I.
登録日2005-12-12
公開日2006-01-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis.
Nat.Chem.Biol., 2, 2006
2FD9
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BU of 2fd9 by Molmil
X-ray Crystal Structure of Chemically Synthesized Crambin-{alpha}carboxamide
分子名称: Crambin
著者Bang, D, Tereshko, V, Kossiakoff, A.A, Kent, S.B.
登録日2005-12-13
公開日2007-01-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Role of a salt bridge in the model protein crambin explored by chemical protein synthesis: X-ray structure of a unique protein analogue, [V15A]crambin-alpha-carboxamide.
Mol Biosyst, 5, 2009
2FCM
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BU of 2fcm by Molmil
X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin with a Cubic Space Group
分子名称: ACETATE ION, CADMIUM ION, Ubiquitin
著者Bang, D, Gribenko, A.V, Tereshko, V, Kossiakoff, A.A, Kent, S.B, Makhatadze, G.I.
登録日2005-12-12
公開日2006-01-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dissecting the energetics of protein alpha-helix C-cap termination through chemical protein synthesis.
Nat.Chem.Biol., 2, 2006
3HHR
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BU of 3hhr by Molmil
HUMAN GROWTH HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR: CRYSTAL STRUCTURE OF THE COMPLEX
分子名称: HUMAN GROWTH HORMONE, HUMAN GROWTH HORMONE RECEPTOR (hGHbp)
著者De Vos, A.M, Ultsch, M, Kossiakoff, A.A.
登録日1993-12-30
公開日1994-04-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human growth hormone and extracellular domain of its receptor: crystal structure of the complex.
Science, 255, 1992
1TAW
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BU of 1taw by Molmil
BOVINE TRYPSIN COMPLEXED TO APPI
分子名称: CALCIUM ION, PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR, TRYPSIN
著者Hynes, T.R, Kossiakoff, A.A.
登録日1996-12-19
公開日1997-06-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities.
Protein Sci., 6, 1997
5UEA
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BU of 5uea by Molmil
Structure of antigen-Fab complex with Histone chaperone ASF1
分子名称: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
著者Bailey, L.J, Kossiakoff, A.A.
登録日2016-12-29
公開日2018-01-10
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
5UEK
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BU of 5uek by Molmil
Structure of antigen-Fab 12E complex with Histone chaperone ASF1
分子名称: Fab 12E Heavy Chain, Fab 12E Light Chain, Histone chaperone ASF1
著者Bailey, L.J, Kossiakoff, A.A.
登録日2017-01-02
公開日2018-01-10
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Antibody Switch Residue Engineering for Improved Crystallization Chaperones
To Be Published
5EII
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BU of 5eii by Molmil
Structural determination of an protein complex of a Fab with increased solubility
分子名称: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
著者Bailey, L.J, Kossiakoff, A.A, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS)
登録日2015-10-29
公開日2016-11-09
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural determination of an protein complex of a Fab with increased solubility
To Be Published
1F6F
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CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN OVINE PLACENTAL LACTOGEN AND THE EXTRACELLULAR DOMAIN OF THE RAT PROLACTIN RECEPTOR
分子名称: PLACENTAL LACTOGEN, PROLACTIN RECEPTOR
著者Elkins, P.A, Christinger, H.W, Sandowski, Y, Sakal, E, Gertler, A, De Vos, A.M, Kossiakoff, A.A.
登録日2000-06-21
公開日2000-07-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.
Nat.Struct.Biol., 7, 2000
4JQI
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BU of 4jqi by Molmil
Structure of active beta-arrestin1 bound to a G protein-coupled receptor phosphopeptide
分子名称: 1,2-ETHANEDIOL, Beta-arrestin-1, CHLORIDE ION, ...
著者Shukla, A.K, Manglik, A, Kruse, A.C, Xiao, K, Reis, R.I, Tseng, W.C, Staus, D.P, Hilger, D, Uysal, S, Huang, L.H, Paduch, M, Shukla, P.T, Koide, A, Koide, S, Weis, W.I, Kossiakoff, A.A, Kobilka, B.K, Lefkowitz, R.J.
登録日2013-03-20
公開日2013-04-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of active beta-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide.
Nature, 497, 2013

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件を2024-10-30に公開中

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