1JMW
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![BU of 1jmw by Molmil](/molmil-images/mine/1jmw) | |
9ICD
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![BU of 9icd by Molmil](/molmil-images/mine/9icd) | CATALYTIC MECHANISM OF NADP+-DEPENDENT ISOCITRATE DEHYDROGENASE: IMPLICATIONS FROM THE STRUCTURES OF MAGNESIUM-ISOCITRATE AND NADP+ COMPLEXES | Descriptor: | ISOCITRATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Hurley, J.H, Dean, A.M, Koshland Jr, D.E, Stroud, R.M. | Deposit date: | 1991-07-29 | Release date: | 1991-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes. Biochemistry, 30, 1991
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2AGE
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![BU of 2age by Molmil](/molmil-images/mine/2age) | Succinyl-AAPR-trypsin acyl-enzyme at 1.15 A resolution | Descriptor: | CALCIUM ION, Cationic trypsin, succinyl-Ala-Ala-Pro-Arg | Authors: | Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2005-07-26 | Release date: | 2006-05-16 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates Proc.Natl.Acad.Sci.USA, 103, 2006
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2AGI
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![BU of 2agi by Molmil](/molmil-images/mine/2agi) | The leupeptin-trypsin covalent complex at 1.14 A resolution | Descriptor: | CALCIUM ION, SULFATE ION, beta-trypsin, ... | Authors: | Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2005-07-26 | Release date: | 2006-05-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates Proc.Natl.Acad.Sci.USA, 103, 2006
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2AH4
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![BU of 2ah4 by Molmil](/molmil-images/mine/2ah4) | guanidinobenzoyl-trypsin acyl-enzyme at 1.13 A resolution | Descriptor: | 4-carbamimidamidobenzoic acid, CALCIUM ION, SULFATE ION, ... | Authors: | Radisky, E.S, Lee, J.M, Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2005-07-26 | Release date: | 2006-05-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates Proc.Natl.Acad.Sci.USA, 103, 2006
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1PB3
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![BU of 1pb3 by Molmil](/molmil-images/mine/1pb3) | |
1PB1
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1OYE
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![BU of 1oye by Molmil](/molmil-images/mine/1oye) | Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump | Descriptor: | 1-CYCLOPROPYL-6-FLUORO-4-OXO-7-PIPERAZIN-1-YL-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID, Acriflavine resistance protein B | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OY9
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![BU of 1oy9 by Molmil](/molmil-images/mine/1oy9) | Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B, ETHIDIUM | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OYD
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![BU of 1oyd by Molmil](/molmil-images/mine/1oyd) | Structural Basis of Multiple Binding Capacity of the AcrB multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B, DEQUALINIUM | Authors: | Yu, E.W, MeDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OY6
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![BU of 1oy6 by Molmil](/molmil-images/mine/1oy6) | Structural Basis of the Multiple Binding Capacity of the AcrB Multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.68 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1OY8
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![BU of 1oy8 by Molmil](/molmil-images/mine/1oy8) | Structural Basis of Multiple Drug Binding Capacity of the AcrB Multidrug Efflux Pump | Descriptor: | Acriflavine resistance protein B, RHODAMINE 6G | Authors: | Yu, E.W, McDermott, G, Zgurskaya, H.I, Nikaido, H, Koshland Jr, D.E. | Deposit date: | 2003-04-03 | Release date: | 2003-05-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.63 Å) | Cite: | Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump. Science, 300, 2003
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1P8F
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1TM7
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![BU of 1tm7 by Molmil](/molmil-images/mine/1tm7) | crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59Y mutant | Descriptor: | CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ... | Authors: | Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2004-06-10 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,). Biochemistry, 43, 2004
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1TM4
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![BU of 1tm4 by Molmil](/molmil-images/mine/1tm4) | crystal structure of the complex of subtilsin BPN'with chymotrypsin inhibitor 2 M59G mutant | Descriptor: | CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ... | Authors: | Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2004-06-10 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,). Biochemistry, 43, 2004
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1TO1
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![BU of 1to1 by Molmil](/molmil-images/mine/1to1) | crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 Y61A mutant | Descriptor: | CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ... | Authors: | Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2004-06-11 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,). Biochemistry, 43, 2004
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1TO2
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![BU of 1to2 by Molmil](/molmil-images/mine/1to2) | crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59K, in pH 9 cryosoak | Descriptor: | CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... | Authors: | Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2004-06-11 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,). Biochemistry, 43, 2004
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1TM5
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![BU of 1tm5 by Molmil](/molmil-images/mine/1tm5) | crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59A mutant | Descriptor: | CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ... | Authors: | Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2004-06-10 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,). Biochemistry, 43, 2004
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1TM1
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![BU of 1tm1 by Molmil](/molmil-images/mine/1tm1) | CRYSTAL STRUCTURE OF THE COMPLEX OF SUBTILISIN BPN' WITH CHYMOTRYPSIN INHIBITOR 2 | Descriptor: | CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ... | Authors: | Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2004-06-10 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,). Biochemistry, 43, 2004
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1TM3
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![BU of 1tm3 by Molmil](/molmil-images/mine/1tm3) | crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59k mutant | Descriptor: | CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ... | Authors: | Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2004-06-10 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,). Biochemistry, 43, 2004
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1TMG
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![BU of 1tmg by Molmil](/molmil-images/mine/1tmg) | crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 M59F mutant | Descriptor: | CALCIUM ION, CITRIC ACID, PENTAETHYLENE GLYCOL, ... | Authors: | Radisky, E.S, Kwan, G, Karen Lu, C.J, Koshland Jr, D.E. | Deposit date: | 2004-06-10 | Release date: | 2004-11-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Binding, Proteolytic, and Crystallographic Analyses of Mutations at the Protease-Inhibitor Interface of the Subtilisin BPN'/Chymotrypsin Inhibitor 2 Complex(,). Biochemistry, 43, 2004
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1LW6
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![BU of 1lw6 by Molmil](/molmil-images/mine/1lw6) | |
1Y3D
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![BU of 1y3d by Molmil](/molmil-images/mine/1y3d) | Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 R67A mutant | Descriptor: | CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... | Authors: | Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. | Deposit date: | 2004-11-24 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2 Biochemistry, 44, 2005
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1Y3B
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![BU of 1y3b by Molmil](/molmil-images/mine/1y3b) | Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 E60S mutant | Descriptor: | CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... | Authors: | Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. | Deposit date: | 2004-11-24 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2 Biochemistry, 44, 2005
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1Y48
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![BU of 1y48 by Molmil](/molmil-images/mine/1y48) | Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 R65A mutant | Descriptor: | CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... | Authors: | Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. | Deposit date: | 2004-11-30 | Release date: | 2005-05-17 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2 Biochemistry, 44, 2005
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