2AGE
Succinyl-AAPR-trypsin acyl-enzyme at 1.15 A resolution
Summary for 2AGE
Entry DOI | 10.2210/pdb2age/pdb |
Related | 2AGG 2AGI 2AH4 |
Related PRD ID | PRD_000351 |
Descriptor | Cationic trypsin, succinyl-Ala-Ala-Pro-Arg, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | acyl-enzyme, serine protease, proteinase, peptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bos taurus (cattle) More |
Cellular location | Secreted, extracellular space: P00760 |
Total number of polymer chains | 2 |
Total formula weight | 23863.93 |
Authors | Radisky, E.S.,Lee, J.M.,Lu, C.J.,Koshland Jr., D.E. (deposition date: 2005-07-26, release date: 2006-05-16, Last modification date: 2024-04-24) |
Primary citation | Radisky, E.S.,Lee, J.M.,Lu, C.J.,Koshland Jr., D.E. Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates Proc.Natl.Acad.Sci.USA, 103:6835-6840, 2006 Cited by PubMed: 16636277DOI: 10.1073/pnas.0601910103 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.15 Å) |
Structure validation
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