2AGE

Succinyl-AAPR-trypsin acyl-enzyme at 1.15 A resolution

Summary for 2AGE

• Entry DOI: 10.2210/pdb2age/pdb
• Related: 2AGG 2AGI 2AH4
• Related PRD ID: PRD_000351
• Descriptor: Cationic trypsin, succinyl-Ala-Ala-Pro-Arg, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: acyl-enzyme, serine protease, proteinase, peptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Bos taurus (cattle); More
• Cellular location: Secreted, extracellular space: P00760
• Total number of polymer chains: 2
• Total formula weight: 23863.93

Authors

Radisky, E.S.,Lee, J.M.,Lu, C.J.,Koshland Jr., D.E. (deposition date: 2005-07-26, release date: 2006-05-16, Last modification date: 2024-04-24)

• Primary citation: Radisky, E.S.,Lee, J.M.,Lu, C.J.,Koshland Jr., D.E.; Insights into the serine protease mechanism from atomic resolution structures of trypsin reaction intermediates; Proc.Natl.Acad.Sci.USA, 103:6835-6840, 2006; PubMed: 16636277; DOI: 10.1073/pnas.0601910103

Experimental method

X-RAY DIFFRACTION (1.15 Å)