4R9U
 
 | | Structure of vitamin B12 transporter BtuCD in a nucleotide-bound outward facing state | | 分子名称: | LAURYL DIMETHYLAMINE-N-OXIDE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Korkhov, V.M, Mireku, S.A, Veprintsev, D.B, Locher, K.P. | | 登録日 | 2014-09-08 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.785 Å) | | 主引用文献 | Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F.
Nat.Struct.Mol.Biol., 21, 2014
|
|
6TD6
 | |
6TBU
 | | Structure of Drosophila melanogaster Dispatched | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Korkhov, V.M, Cannac, F. | | 登録日 | 2019-11-04 | | 公開日 | 2020-06-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Cryo-EM structure of the Hedgehog release protein Dispatched.
Sci Adv, 6, 2020
|
|
4DBL
 | | Crystal structure of E159Q mutant of BtuCDF | | 分子名称: | PHOSPHATE ION, SULFATE ION, Vitamin B12 import ATP-binding protein BtuD, ... | | 著者 | Korkhov, V.M, Mireku, S.M, Hvorup, R.N, Locher, K.P. | | 登録日 | 2012-01-16 | | 公開日 | 2012-03-07 | | 最終更新日 | 2012-05-23 | | 実験手法 | X-RAY DIFFRACTION (3.493 Å) | | 主引用文献 | Asymmetric states of vitamin B12 transporter BtuCD are not discriminated by its cognate substrate binding protein BtuF.
Febs Lett., 586, 2012
|
|
4FI3
 | | Structure of vitamin B12 transporter BtuCD-F in a nucleotide-bound state | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Vitamin B12 import ATP-binding protein BtuD, ... | | 著者 | Korkhov, V.M, Mireku, S.A, Locher, K.P. | | 登録日 | 2012-06-07 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.466 Å) | | 主引用文献 | Structure of AMP-PNP-bound vitamin B12 transporter BtuCD-F.
Nature, 490, 2012
|
|
7NUR
 | |
6RMG
 | | Structure of PTCH1 bound to a modified Hedgehog ligand ShhN-C24II | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Korkhov, V.M, Qi, C. | | 登録日 | 2019-05-06 | | 公開日 | 2019-10-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of sterol recognition by human hedgehog receptor PTCH1.
Sci Adv, 5, 2019
|
|
6R3Q
 | |
6R4P
 | |
8BUZ
 | | Structure of Adenylyl cyclase 8 bound to stimulatory G-protein, Ca2+/Calmodulin, Forskolin and MANT-GTP | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 8, FORSKOLIN, ... | | 著者 | Khanppnavar, B, Korkhov, V.M, Mehta, V. | | 登録日 | 2022-12-01 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics.
Embo Rep., 25, 2024
|
|
8BV5
 | | Focus refinement of soluble domain of Adenylyl cyclase 8 bound to stimulatory G protein, Forskolin, ATPalphaS, and Ca2+/Calmodulin in lipid nanodisc conditions | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 8, FORSKOLIN, ... | | 著者 | Khanppnavar, B, Korkhov, V.M. | | 登録日 | 2023-01-04 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics.
Embo Rep., 25, 2024
|
|
5O5K
 | |
5O5L
 | |
7ZXN
 | |
7ZXO
 | |
7ZXQ
 | |
7ZXP
 | |
7ZXM
 | |
7ZXT
 | |
6R4O
 | | Structure of a truncated adenylyl cyclase bound to MANT-GTP, forskolin and an activated stimulatory Galphas protein | | 分子名称: | 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, ... | | 著者 | Qi, C, Sorrentino, S, Medalia, O, Korkhov, V.M. | | 登録日 | 2019-03-22 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.
Science, 364, 2019
|
|
7YZI
 | | Structure of Mycobacterium tuberculosis adenylyl cyclase Rv1625c / Cya | | 分子名称: | 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, MANGANESE (II) ION, ... | | 著者 | Mehta, V, Khanppnavar, B, Korkhov, V.M. | | 登録日 | 2022-02-20 | | 公開日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.83 Å) | | 主引用文献 | Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases.
Elife, 11, 2022
|
|
7YZ9
 | | Structure of catalytic domain of Rv1625c bound to nanobody NB4 | | 分子名称: | 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, GLYCEROL, ... | | 著者 | Khanppnavar, B, Mehta, V.J, Iype, T, Korkhov, V.M. | | 登録日 | 2022-02-19 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases.
Elife, 11, 2022
|
|
7YZK
 | | Structure of Mycobacterium tuberculosis adenylyl cyclase Rv1625c / Cya | | 分子名称: | 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, MANGANESE (II) ION, ... | | 著者 | Mehta, V, Khanppnavar, B, Korkhov, V.M. | | 登録日 | 2022-02-20 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | | 主引用文献 | Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases.
Elife, 11, 2022
|
|
8R7Q
 | |
8R7P
 | |
