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PDB: 25 件

2F23
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Crystal structure of GreA factor homolog 1 (Gfh1) protein of Thermus thermophilus
分子名称: Anti-cleavage anti-greA transcription factor gfh1
著者Kong, X.P, Kim, S.-S.
登録日2005-11-15
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献pH-dependent conformational switch activates the inhibitor of transcription elongation.
Embo J., 25, 2006
3UJI
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BU of 3uji by Molmil
Crystal structure of anti-HIV-1 V3 Fab 2558 in complex with MN peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein gp160, ...
著者Kong, X.P.
登録日2011-11-07
公開日2011-12-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure.
Plos One, 6, 2011
3UJJ
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Crystal structure of anti-HIV-1 V3 Fab 4025 in complex with Con A peptide
分子名称: ACETATE ION, Fab region of the heavy chain of anti-HIV-1 V3 monoclonal antibody 4025, GLYCEROL, ...
著者Kong, X.P, Sampson, J.
登録日2011-11-07
公開日2011-12-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human Anti-V3 HIV-1 Monoclonal Antibodies Encoded by the VH5-51/VL Lambda Genes Define a Conserved Antigenic Structure.
Plos One, 6, 2011
3GHB
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BU of 3ghb by Molmil
Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 peptide W2RW020
分子名称: Envelope glycoprotein, Fab 447-52D, heavy chain, ...
著者Kong, X.P, Burke, V.J.
登録日2009-03-03
公開日2009-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis of the cross-reactivity of genetically related human anti-HIV-1 mAbs: implications for design of V3-based immunogens
Structure, 17, 2009
3GO1
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BU of 3go1 by Molmil
Crystal structure of anti-HIV-1 Fab 268-D in complex with V3 peptide MN
分子名称: Envelope glycoprotein gp160, Fab 268-D, heavy chain, ...
著者Kong, X.P, Burke, V.J.
登録日2009-03-18
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Conserved structural elements in the V3 crown of HIV-1 gp120.
Nat.Struct.Mol.Biol., 17, 2010
3GHE
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BU of 3ghe by Molmil
Crystal structure of anti-HIV-1 Fab 537-10D in complex with V3 peptide MN
分子名称: Envelope glycoprotein, Fab 537-10D, heavy chain, ...
著者Kong, X.P, Burke, V.J.
登録日2009-03-03
公開日2009-12-01
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of the cross-reactivity of genetically related human anti-HIV-1 mAbs: implications for design of V3-based immunogens
Structure, 17, 2009
1HXW
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BU of 1hxw by Molmil
HIV-1 PROTEASE DIMER COMPLEXED WITH A-84538
分子名称: HIV-1 PROTEASE, RITONAVIR
著者Park, C.H, Nienaber, V, Kong, X.P.
登録日1997-01-24
公開日1998-02-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献ABT-538 is a potent inhibitor of human immunodeficiency virus protease and has high oral bioavailability in humans.
Proc.Natl.Acad.Sci.USA, 92, 1995
7RAI
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Cryo-EM structure of M4008_N1 Fab in complex with BG505 DS-SOSIP.664 Env trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Chan, K.-W, Kong, X.P.
登録日2021-07-01
公開日2021-11-17
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献A site of vulnerability at V3 crown defined by HIV-1 bNAb M4008_N1.
Nat Commun, 12, 2021
4D9L
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Fab structure of anti-HIV-1 gp120 V2 mAb 697
分子名称: Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 697
著者Pan, R.M, Kong, X.P.
登録日2012-01-11
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.485 Å)
主引用文献Functional and immunochemical cross-reactivity of V2-specific monoclonal antibodies from HIV-1-infected individuals.
Virology, 427, 2012
1PRO
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BU of 1pro by Molmil
HIV-1 PROTEASE DIMER COMPLEXED WITH A-98881
分子名称: (5R,6R)-2,4-BIS-(4-HYDROXY-3-METHOXYBENZYL)-1,5-DIBENZYL-3-OXO-6-HYDROXY-1,2,4-TRIAZACYCLOHEPTANE, HIV-1 PROTEASE
著者Park, C.H, Kong, X.P, Dealwis, C.G.
登録日1995-07-18
公開日1996-08-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A novel, picomolar inhibitor of human immunodeficiency virus type 1 protease.
J.Med.Chem., 39, 1996
8TR3
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BU of 8tr3 by Molmil
Cryo-EM structure of HmAb64 scFv in complex with CNE40 SOSIP trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CNE40 SOSIP Envelope glycoprotein gp120, ...
著者Chan, K.-W, Kong, X.P.
登録日2023-08-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains.
Nat Commun, 15, 2024
6VY2
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BU of 6vy2 by Molmil
Cryo-EM structure of M1214_N1 Fab in complex with CH505 TF chimeric SOSIP.664 Env trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein 120, ...
著者Chan, K.-W, Kong, X.P.
登録日2020-02-25
公開日2020-05-06
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.86 Å)
主引用文献VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA.
Cell Host Microbe, 27, 2020
3RQW
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Crystal structure of acetylcholine bound to a prokaryotic pentameric ligand-gated ion channel, ELIC
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYLCHOLINE, ELIC Pentameric Ligand Gated Ion Channel from Erwinia Chrysanthemi, ...
著者Pan, J.J, Chen, Q, Yoshida, K, Cohen, A, Kong, X.P, Xu, Y, Tang, P.
登録日2011-04-28
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.913 Å)
主引用文献Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine.
Nat Commun, 3, 2012
3Q6F
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Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120
分子名称: DI(HYDROXYETHYL)ETHER, Heavy chain of Fab of human mAb 2909, Light chain of Fab of human mAb 2909
著者Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P.
登録日2010-12-31
公開日2011-05-25
最終更新日2011-10-12
実験手法X-RAY DIFFRACTION (3.192 Å)
主引用文献Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
3Q6G
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BU of 3q6g by Molmil
Crystal structure of Fab of rhesus mAb 2.5B specific for quaternary neutralizing epitope of HIV-1 gp120
分子名称: Heavy chain of Fab of rhesus mAb 2.5B, Light chain of Fab of rhesus mAb 2.5B
著者Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P.
登録日2010-12-31
公開日2011-05-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
3RQU
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BU of 3rqu by Molmil
Crystal structure of a prokaryotic pentameric ligand-gated ion channel, ELIC
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ELIC Pentameric Ligand Gated Ion Channel from Erwinia Chrysanthemi, GLYCEROL
著者Pan, J.J, Chen, Q, Yoshida, K, Cohen, A, Kong, X.P, Xu, Y, Tang, P.
登録日2011-04-28
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.089 Å)
主引用文献Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine.
Nat Commun, 3, 2012
4F58
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Fab structure of a neutralizing antibody L3 from an early subtype A HIV-1 infected patient
分子名称: Heavy chain of Fab of a neutralizing antibody L3, Light chain of Fab of a neutralizing antibody L3, SULFATE ION
著者Pan, R.M, Kong, X.P.
登録日2012-05-12
公開日2013-03-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.488 Å)
主引用文献Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth.
Plos Pathog., 9, 2013
4F8H
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X-ray Structure of the Anesthetic Ketamine Bound to the GLIC Pentameric Ligand-gated Ion Channel
分子名称: (R)-ketamine, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Proton-gated ion channel, ...
著者Pan, J.J, Chen, Q, Willenbring, D, Kong, X.P, Cohen, A, Xu, Y, Tang, P.
登録日2012-05-17
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine.
Structure, 20, 2012
4JO4
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Crystal structure of rabbit mAb R20 Fab
分子名称: PENTAETHYLENE GLYCOL, SULFATE ION, monoclonal anti-HIV-1 gp120 V3 antibody R20 heavy chain, ...
著者Pan, R.M, Kong, X.P.
登録日2013-03-16
公開日2013-07-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
4JO3
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Crystal structure of rabbit mAb R20 Fab in complex with V3 C-terminus of HIV-1 Consensus B gp120
分子名称: SULFATE ION, gp120, monoclonal anti-HIV-1 gp120 V3 antibody R20 heavy chain, ...
著者Pan, R.M, Kong, X.P.
登録日2013-03-16
公開日2013-07-31
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
4JO1
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Crystal structure of rabbit mAb R56 Fab in complex with V3 crown of HIV-1 JR-FL gp120
分子名称: CALCIUM ION, gp120, monoclonal anti-HIV-1 gp120 V3 antibody R56 heavy chain, ...
著者Pan, R.M, Kong, X.P.
登録日2013-03-16
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.033 Å)
主引用文献Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
4F57
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Fab structure of a neutralizing antibody L1 from an early subtype A HIV-1 infected patient
分子名称: GLYCEROL, Heavy chain of Fab of a neutralizing antibody L1, Light chain of Fab of a neutralizing antibody L1
著者Pan, R.M, Kong, X.P.
登録日2012-05-12
公開日2013-03-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth.
Plos Pathog., 9, 2013
4JO2
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Crystal structure of rabbit mAb R56 Fab in complex with V3 crown of HIV-1 Consensus A gp120
分子名称: CALCIUM ION, gp120, monoclonal anti-HIV-1 gp120 V3 antibody R56 heavy chain, ...
著者Pan, R.M, Kong, X.P.
登録日2013-03-16
公開日2013-07-31
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
4M1D
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Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 cyclic peptide MN
分子名称: Cyclic V3 Arch Peptide, Fab mAb 447-52D Heavy Chain, Fab mAb 447-52D Light Chain, ...
著者Killikelly, A, Kong, X.P.
登録日2013-08-02
公開日2013-09-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Thermodynamic Signatures of the Antigen Binding Site of mAb 447-52D Targeting the Third Variable Region of HIV-1 gp120.
Biochemistry, 52, 2013
4OAW
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Fab structure of anti-HIV gp120 V2 mAb 2158
分子名称: GLYCEROL, Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 2158, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 2158, ...
著者Spurrier, B.R, Kong, X.P.
登録日2014-01-06
公開日2014-03-19
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Functional Implications of the Binding Mode of a Human Conformation-Dependent V2 Monoclonal Antibody against HIV.
J.Virol., 88, 2014

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