4JO4
 
 | | Crystal structure of rabbit mAb R20 Fab | | 分子名称: | PENTAETHYLENE GLYCOL, SULFATE ION, monoclonal anti-HIV-1 gp120 V3 antibody R20 heavy chain, ... | | 著者 | Pan, R.M, Kong, X.P. | | 登録日 | 2013-03-16 | | 公開日 | 2013-07-31 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Rabbit Anti-HIV-1 Monoclonal Antibodies Raised by Immunization Can Mimic the Antigen-Binding Modes of Antibodies Derived from HIV-1-Infected Humans.
J.Virol., 87, 2013
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3RQW
 | | Crystal structure of acetylcholine bound to a prokaryotic pentameric ligand-gated ion channel, ELIC | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYLCHOLINE, ELIC Pentameric Ligand Gated Ion Channel from Erwinia Chrysanthemi, ... | | 著者 | Pan, J.J, Chen, Q, Yoshida, K, Cohen, A, Kong, X.P, Xu, Y, Tang, P. | | 登録日 | 2011-04-28 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.913 Å) | | 主引用文献 | Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine.
Nat Commun, 3, 2012
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5V6M
 | | Crystal Structure of Rabbit Anti-HIV-1 gp120 V3 Fab 10A3 in complex with V3 peptide ConB | | 分子名称: | CALCIUM ION, Envelope glycoprotein gp120 V3 peptide of Con B sequence, Heavy chain of Fab fragment of rabbit anti-HIV1 gp120 V3 mAb 10A3, ... | | 著者 | Pan, R, Kong, X.-P. | | 登録日 | 2017-03-17 | | 公開日 | 2018-01-17 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Increased epitope complexity correlated with antibody affinity maturation and a novel binding mode revealed by structures of rabbit antibodies against the third variable loop (V3) of HIV-1 gp120.
J. Virol., 2018
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5V6L
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3RQU
 | | Crystal structure of a prokaryotic pentameric ligand-gated ion channel, ELIC | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ELIC Pentameric Ligand Gated Ion Channel from Erwinia Chrysanthemi, GLYCEROL | | 著者 | Pan, J.J, Chen, Q, Yoshida, K, Cohen, A, Kong, X.P, Xu, Y, Tang, P. | | 登録日 | 2011-04-28 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.089 Å) | | 主引用文献 | Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine.
Nat Commun, 3, 2012
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3BEP
 | | Structure of a sliding clamp on DNA | | 分子名称: | 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium, DNA (5'-D(*DTP*DTP*DTP*DTP*DAP*DTP*DAP*DCP*DGP*DAP*DTP*DGP*DGP*DG)-3'), DNA (5'-D(P*DCP*DCP*DCP*DAP*DTP*DCP*DGP*DTP*DAP*DT)-3'), ... | | 著者 | Georgescu, R.E, Kim, S.S, Yurieva, O, Kuriyan, J, Kong, X.-P, O'Donnell, M. | | 登録日 | 2007-11-19 | | 公開日 | 2008-01-29 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structure of a sliding clamp on DNA
Cell(Cambridge,Mass.), 132, 2008
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3Q6G
 | | Crystal structure of Fab of rhesus mAb 2.5B specific for quaternary neutralizing epitope of HIV-1 gp120 | | 分子名称: | Heavy chain of Fab of rhesus mAb 2.5B, Light chain of Fab of rhesus mAb 2.5B | | 著者 | Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P. | | 登録日 | 2010-12-31 | | 公開日 | 2011-05-25 | | 最終更新日 | 2013-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | | 主引用文献 | Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
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3QPD
 | | Structure of Aspergillus oryzae cutinase expressed in Pichia pastoris, crystallized in the presence of Paraoxon | | 分子名称: | Cutinase 1 | | 著者 | Lu, A, Gosser, Y, Montclare, J.K, Liu, Z, Kong, X. | | 登録日 | 2011-02-11 | | 公開日 | 2012-02-29 | | 実験手法 | X-RAY DIFFRACTION (1.571 Å) | | 主引用文献 | Structure of Aspergillus oryzae cutinase expressed in Pichia pastoris, crystallized in the presence of Paraoxon
To be Published
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3Q6F
 | | Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Heavy chain of Fab of human mAb 2909, Light chain of Fab of human mAb 2909 | | 著者 | Spurrier, B, Sampson, J, Totrov, M, Li, H, O'Neal, T, William, C, Robinson, J, Gorny, M.K, Zolla-Pazner, S, Kong, X.P. | | 登録日 | 2010-12-31 | | 公開日 | 2011-05-25 | | 最終更新日 | 2011-10-12 | | 実験手法 | X-RAY DIFFRACTION (3.192 Å) | | 主引用文献 | Structural Analysis of Human and Macaque mAbs 2909 and 2.5B: Implications for the Configuration of the Quaternary Neutralizing Epitope of HIV-1 gp120.
Structure, 19, 2011
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3QPA
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3QPC
 | | Structure of Fusarium Solani Cutinase expressed in Pichia pastoris, crystallized in the presence of Paraoxon | | 分子名称: | Cutinase | | 著者 | Lu, A, Gosser, Y, Montclare, J.K, Liu, Z, Kong, X. | | 登録日 | 2011-02-11 | | 公開日 | 2012-02-29 | | 実験手法 | X-RAY DIFFRACTION (0.978 Å) | | 主引用文献 | Structure of Fusarium Solani Cutinase expressed in Pichia pastoris
To be Published
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4YWG
 | | Crystal structure of 830A in complex with V1V2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of anti-HIV-1 gp120 V1V2 antibody 830A, Light chain of anti-HIV-1 gp120 V1V2 antibody 830A, ... | | 著者 | Pan, R, Kong, X. | | 登録日 | 2015-03-20 | | 公開日 | 2015-07-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | | 主引用文献 | The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel.
J.Virol., 89, 2015
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8DGG
 | | Structure of glycosylated LAG-3 homodimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Silberstein, J.L, Mathews, I.I, Frank, J.A, Chan, K.-W, Fernandez, D, Du, J, Wang, J, Kong, X.-P, Cochran, J.R. | | 登録日 | 2022-06-23 | | 公開日 | 2022-08-17 | | 最終更新日 | 2022-08-31 | | 実験手法 | X-RAY DIFFRACTION (3.78 Å) | | 主引用文献 | Structural basis for LAG-3 dimeric association and inhibition of T cell function
To Be Published
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4ZTO
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4ZTP
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4O98
 | | Crystal structure of Pseudomonas oleovorans PoOPH mutant H250I/I263W | | 分子名称: | ZINC ION, organophosphorus hydrolase | | 著者 | Luo, X.J, Kong, X.D, Zhao, J, Chen, Q, Zhou, J.H, Xu, J.H. | | 登録日 | 2014-01-02 | | 公開日 | 2014-12-03 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | | 主引用文献 | Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp
Biotechnol.Bioeng., 111, 2014
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4M1D
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4OB6
 | | Complex structure of esterase rPPE S159A/W187H and substrate (S)-Ac-CPA | | 分子名称: | (2S)-(acetyloxy)(2-chlorophenyl)ethanoic acid, Alpha/beta hydrolase fold-3 domain protein | | 著者 | Dou, S, Kong, X.D, Ma, B.D, Chen, Q, Zhou, J.H, Xu, J.H. | | 登録日 | 2014-01-07 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
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4OU4
 | | Crystal structure of esterase rPPE mutant S159A complexed with (S)-Ac-CPA | | 分子名称: | (2S)-(acetyloxy)(2-chlorophenyl)ethanoic acid, Alpha/beta hydrolase fold-3 domain protein | | 著者 | Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H. | | 登録日 | 2014-02-15 | | 公開日 | 2014-07-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
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4OB8
 | | Crystal structure of a novel thermostable esterase from Pseudomonas putida ECU1011 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha/beta hydrolase fold-3 domain protein, DI(HYDROXYETHYL)ETHER | | 著者 | Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H. | | 登録日 | 2014-01-07 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
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4OB7
 | | Crystal structure of esterase rPPE mutant W187H | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha/beta hydrolase fold-3 domain protein, DI(HYDROXYETHYL)ETHER | | 著者 | Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H. | | 登録日 | 2014-01-07 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
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4OU5
 | | Crystal structure of esterase rPPE mutant S159A/W187H | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha/beta hydrolase fold-3 domain protein, DI(HYDROXYETHYL)ETHER | | 著者 | Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H. | | 登録日 | 2014-02-15 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
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4OAW
 | | Fab structure of anti-HIV gp120 V2 mAb 2158 | | 分子名称: | GLYCEROL, Heavy chain of Fab fragment of anti-HIV1 gp120 V2 mAb 2158, Light chain of Fab fragment of anti-HIV1 gp120 V2 mAb 2158, ... | | 著者 | Spurrier, B.R, Kong, X.P. | | 登録日 | 2014-01-06 | | 公開日 | 2014-03-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Functional Implications of the Binding Mode of a Human Conformation-Dependent V2 Monoclonal Antibody against HIV.
J.Virol., 88, 2014
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5UBY
 | | Fab structure of anti-HIV-1 gp120 mAb 1A8 | | 分子名称: | Heavy chain of Fab fragment of anti-HIV1 gp120 mAb 1A8, Light chain of Fab fragment of anti-HIV1 gp120 mAb 1A8 | | 著者 | Pan, R, Kong, X.-P. | | 登録日 | 2016-12-21 | | 公開日 | 2018-01-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | High Antibody Diversity and Low Inter-clonal Competition Favor Production of Functional Neutralizing Antibodies
To be Published
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5UBZ
 | | Fab structure of HIV gp120 specific mAb 1E12 | | 分子名称: | Anti-HIV1 gp120 mAb 1E12 Fab heavy chain, Anti-HIV1 gp120 mAb 1E12 Fab light chain | | 著者 | Pan, R, Kong, X.-P. | | 登録日 | 2016-12-21 | | 公開日 | 2018-01-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | High Antibody Diversity and Low Inter-clonal Competition Favor Production of Functional Neutralizing Antibodies
To be published
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