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PDB: 15 件
7QQ3
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Cryo-EM structure of the E.coli 50S ribosomal subunit in complex with the antibiotic Myxovalargin A.
分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Koller, T.O, Beckert, B, Wilson, D.N.
登録日2022-01-06
公開日2023-01-18
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
J.Am.Chem.Soc., 145, 2023
7AZY
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Context-specific inhibition of eukaryotic translation by macrolide antibiotics
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Koller, T.O, Wilson, D.N.
登録日2020-11-17
公開日2021-05-19
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.877 Å)
主引用文献Context-specific action of macrolide antibiotics on the eukaryotic ribosome.
Nat Commun, 12, 2021
9FBV
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BU of 9fbv by Molmil
70S Escherichia coli ribosome with P-site initiatior tRNA.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S16, ...
著者Koller, T.O, Wilson, D.N.
登録日2024-05-14
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis.
Biorxiv, 2024
8B7Y
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Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Koller, T.O, Graf, M, Wilson, D.N.
登録日2022-10-03
公開日2023-01-25
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition.
J.Am.Chem.Soc., 145, 2023
8A5I
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BU of 8a5i by Molmil
Cryo-EM structure of Lincomycin bound to the Listeria monocytogenes 50S ribosomal subunit.
分子名称: 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L13, ...
著者Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N.
登録日2022-06-15
公開日2022-11-02
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes.
Nucleic Acids Res., 50, 2022
8A63
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Cryo-EM structure of Listeria monocytogenes 50S ribosomal subunit.
分子名称: 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L13, ...
著者Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N.
登録日2022-06-16
公開日2022-11-02
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes.
Nucleic Acids Res., 50, 2022
8A57
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Cryo-EM structure of HflXr bound to the Listeria monocytogenes 50S ribosomal subunit.
分子名称: 1,4-DIAMINOBUTANE, 23S ribosomal RNA, 50S ribosomal protein L11, ...
著者Koller, T.O, Crowe-McAuliffe, C, Wilson, D.N.
登録日2022-06-14
公開日2022-11-02
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes.
Nucleic Acids Res., 50, 2022
8AKN
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Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the terminating ribosome
分子名称: 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ...
著者Koller, T.O, Morici, M, Wilson, D.N.
登録日2022-07-30
公開日2023-03-08
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structural basis for translation inhibition by the glycosylated drosocin peptide.
Nat.Chem.Biol., 19, 2023
8ANA
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BU of 8ana by Molmil
Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the 50S ribosomal subunit
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, 50S ribosomal protein L13, ...
著者Koller, T.O, Morici, M, Wilson, D.N.
登録日2022-08-05
公開日2023-03-08
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Structural basis for translation inhibition by the glycosylated drosocin peptide.
Nat.Chem.Biol., 19, 2023
8AM9
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BU of 8am9 by Molmil
Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the elongating ribosome
分子名称: 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ...
著者Koller, T.O, Morici, M, Wilson, D.N.
登録日2022-08-03
公開日2023-03-08
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for translation inhibition by the glycosylated drosocin peptide.
Nat.Chem.Biol., 19, 2023
7OTC
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BU of 7otc by Molmil
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with elongation factor G and the antibiotic Argyrin B
分子名称: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
著者Wieland, M, Koller, T.O, Wilson, D.N.
登録日2021-06-10
公開日2022-05-11
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UG7
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BU of 7ug7 by Molmil
70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B
分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
著者Rundlet, E.J, Wieland, M, Holm, M, Koller, T.O, Blanchard, S.C, Wilson, D.N.
登録日2022-03-24
公開日2022-05-18
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Proc.Natl.Acad.Sci.USA, 119, 2022
8CGD
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BU of 8cgd by Molmil
Clindamycin bound to the 50S subunit
分子名称: 23S rRNA, 50S ribosomal protein L15, 50S ribosomal protein L25, ...
著者Paternoga, H, Koller, T.O, Beckert, B, Wilson, D.N.
登録日2023-02-03
公開日2023-07-26
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (1.98 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CGR
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BU of 8cgr by Molmil
Apramycin bound to the 30S body
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ...
著者Paternoga, H, Koller, T.O, Beckert, B, Wilson, D.N.
登録日2023-02-06
公開日2023-07-26
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.12 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CF8
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BU of 8cf8 by Molmil
Eravacycline bound to the 30S head
分子名称: 16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S7, ...
著者Paternoga, H, Koller, T.O, Beckert, B, Wilson, D.N.
登録日2023-02-03
公開日2023-08-02
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023

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件を2024-07-17に公開中

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