7OTC
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with elongation factor G and the antibiotic Argyrin B
This is a non-PDB format compatible entry.
Summary for 7OTC
Entry DOI | 10.2210/pdb7otc/pdb |
Related | 7UG7 |
EMDB information | 13058 26486 |
Descriptor | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (59 entities in total) |
Functional Keywords | antibiotic, ribosome, translation |
Biological source | Escherichia coli BL21(DE3) More |
Total number of polymer chains | 52 |
Total formula weight | 2188658.26 |
Authors | Wieland, M.,Koller, T.O.,Wilson, D.N. (deposition date: 2021-06-10, release date: 2022-05-11, Last modification date: 2024-04-24) |
Primary citation | Wieland, M.,Holm, M.,Rundlet, E.J.,Morici, M.,Koller, T.O.,Maviza, T.P.,Pogorevc, D.,Osterman, I.A.,Muller, R.,Blanchard, S.C.,Wilson, D.N. The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation. Proc.Natl.Acad.Sci.USA, 119:e2114214119-e2114214119, 2022 Cited by PubMed: 35500116DOI: 10.1073/pnas.2114214119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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