3PLN
 
 | | Crystal structure of Klebsiella pneumoniae UDP-glucose 6-dehydrogenase complexed with UDP-glucose | | Descriptor: | UDP-glucose 6-dehydrogenase, URIDINE-5'-MONOPHOSPHATE | | Authors: | Chen, Y.-Y, Ko, T.-P, Lin, C.-H, Chen, W.-H, Wang, A.H.-J. | | Deposit date: | 2010-11-15 | | Release date: | 2011-09-28 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
J.Struct.Biol., 175, 2011
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8J0A
 | | Robust design of effective allosteric activator UbV R4 for Rsp5 E3 ligase using the machine-learning tool ProteinMPNN | | Descriptor: | SULFATE ION, Ubiquitin variant R4 | | Authors: | Lin, Y.-F, Hsieh, Y.-J, Kao, H.-W, Ko, T.-P, Wu, K.-P. | | Deposit date: | 2023-04-10 | | Release date: | 2023-08-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Robust Design of Effective Allosteric Activators for Rsp5 E3 Ligase Using the Machine Learning Tool ProteinMPNN.
Acs Synth Biol, 12, 2023
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2DH4
 | | Geranylgeranyl pyrophosphate synthase | | Descriptor: | MAGNESIUM ION, YPL069C | | Authors: | Chang, T.-H, Guo, R.-T, Ko, T.-P, Wang, A.H, Liang, P.-H. | | Deposit date: | 2006-03-22 | | Release date: | 2006-04-04 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Crystal Structure of Type-III Geranylgeranyl Pyrophosphate Synthase from Saccharomyces cerevisiae and the Mechanism of Product Chain Length Determination.
J.Biol.Chem., 281, 2006
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3OAB
 | | Mint deletion mutant of heterotetrameric geranyl pyrophosphate synthase in complex with ligands | | Descriptor: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... | | Authors: | Hsieh, F.-L, Chang, T.-H, Ko, T.-P, Wang, A.H.-J. | | Deposit date: | 2010-08-05 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Enhanced specificity of mint geranyl pyrophosphate synthase by modifying the R-loop interactions
J.Mol.Biol., 404, 2010
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3OAC
 | | Mint deletion mutant of heterotetrameric geranyl pyrophosphate synthase in complex with ligands | | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, Geranyl diphosphate synthase large subunit, ... | | Authors: | Hsieh, F.-L, Chang, T.-H, Ko, T.-P, Wang, A.H.-J. | | Deposit date: | 2010-08-05 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Enhanced specificity of mint geranyl pyrophosphate synthase by modifying the R-loop interactions
J.Mol.Biol., 404, 2010
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5FNP
 | | High resolution Zn containing Iron sulfur cluster repair protein YtfE | | Descriptor: | CHLORIDE ION, IRON-SULFUR CLUSTER REPAIR PROTEIN YTFE, OXYGEN ATOM, ... | | Authors: | Lo, F.-C, Hsieh, C.-C, Maestre-Reyna, M, Chen, C.-Y, Ko, T.-P, Horng, Y.-C, Lai, Y.-C, Chiang, Y.-W, Chou, C.-M, Chiang, C.-H, Huang, W.-N, Liaw, W.-F. | | Deposit date: | 2015-11-16 | | Release date: | 2016-04-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal Structure of the Repair of Iron Centers Protein Ytfe and its Interaction with No
Chemistry, 22, 2016
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5FNN
 | | Iron and Selenomethionine containing Iron sulfur cluster repair protein YtfE | | Descriptor: | CHLORIDE ION, FE (II) ION, FE (III) ION, ... | | Authors: | Lo, F.-C, Hsieh, C.-C, Maestre-Reyna, M, Chen, C.-Y, Ko, T.-P, Horng, Y.-C, Lai, Y.-C, Chiang, Y.-W, Chou, C.-M, Chiang, C.-H, Huang, W.-N, Liaw, W.-F. | | Deposit date: | 2015-11-16 | | Release date: | 2016-04-27 | | Last modified: | 2017-07-12 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Crystal Structure of the Repair of Iron Centers Protein Ytfe and its Interaction with No
Chemistry, 22, 2016
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5FNY
 | | Low solvent content crystal form of Zn containing Iron sulfur cluster repair protein YtfE | | Descriptor: | FE (III) ION, IRON-SULFUR CLUSTER REPAIR PROTEIN YTFE, NONAETHYLENE GLYCOL, ... | | Authors: | Lo, F.-C, Hsieh, C.-C, Maestre-Reyna, M, Chen, C.-Y, Ko, T.-P, Horng, Y.-C, Lai, Y.-C, Chiang, Y.-W, Chou, C.-M, Chiang, C.-H, Huang, W.-N, Liaw, W.-F. | | Deposit date: | 2015-11-17 | | Release date: | 2016-04-27 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Crystal Structure of the Repair of Iron Centers Protein Ytfe and its Interaction with No
Chemistry, 22, 2016
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1UEH
 | | E. coli undecaprenyl pyrophosphate synthase in complex with Triton X-100, magnesium and sulfate | | Descriptor: | MAGNESIUM ION, OXTOXYNOL-10, SULFATE ION, ... | | Authors: | Chang, S.-Y, Ko, T.-P, Liang, P.-H, Wang, A.H.-J. | | Deposit date: | 2003-05-15 | | Release date: | 2003-08-12 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Catalytic mechanism revealed by the crystal structure of undecaprenyl pyrophosphate synthase in complex with sulfate, magnesium, and triton
J.Biol.Chem., 278, 2003
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7YQN
 | | Crystal structure of Ecoli malate synthase G | | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ... | | Authors: | Wu, K.-P, Lu, Y.-C, Ko, T.-P. | | Deposit date: | 2022-08-08 | | Release date: | 2023-03-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Cryo-EM reveals the structure and dynamics of a 723-residue malate synthase G.
J.Struct.Biol., 215, 2023
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2ZWY
 | | alpha-L-fucosidase | | Descriptor: | Alpha-L-fucosidase, putative | | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | | Deposit date: | 2008-12-18 | | Release date: | 2009-12-08 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural Basis of alpha-Fucosidase Inhibition by Iminocyclitols with Ki Ranging from Micro- to Picomolar
To be Published
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2ZX8
 | | alpha-L-fucosidase complexed with inhibitor, F10-2C-O | | Descriptor: | Alpha-L-fucosidase, putative, N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}-1-benzofuran-2-carboxamide | | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | | Deposit date: | 2008-12-19 | | Release date: | 2009-12-08 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
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3KRF
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium, IPP, and DMASPP (I) | | Descriptor: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... | | Authors: | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | Deposit date: | 2009-11-18 | | Release date: | 2010-02-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3KRC
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with IPP | | Descriptor: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Geranyl diphosphate synthase large subunit, ... | | Authors: | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | Deposit date: | 2009-11-18 | | Release date: | 2010-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3KRP
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium and GPP | | Descriptor: | 1,2-ETHANEDIOL, GERANYL DIPHOSPHATE, Geranyl diphosphate synthase large subunit, ... | | Authors: | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | Deposit date: | 2009-11-19 | | Release date: | 2010-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3LCF
 | | The D-sialic acid aldolase mutant V251I | | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-11 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3LCX
 | | L-KDO aldolase | | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Huang, K.-F, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-12 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3LCG
 | | The D-sialic acid aldolase mutant V251L | | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-11 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3LCI
 | | The D-sialic acid aldolase mutant V251W | | Descriptor: | N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-11 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3LCW
 | | L-KDO aldolase complexed with hydroxypyruvate | | Descriptor: | 3-HYDROXYPYRUVIC ACID, N-acetylneuraminate lyase, SULFATE ION | | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | | Deposit date: | 2010-01-12 | | Release date: | 2011-01-19 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251
To be Published
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3MBR
 | | Crystal Structure of the Glutaminyl Cyclase from Xanthomonas campestris | | Descriptor: | CALCIUM ION, Glutamine cyclotransferase | | Authors: | Huang, W.-L, Wang, Y.-R, Ko, T.-P, Chia, C.-Y, Huang, K.-F, Wang, A.H.-J. | | Deposit date: | 2010-03-25 | | Release date: | 2010-06-30 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Crystal structure and functional analysis of the glutaminyl cyclase from Xanthomonas campestris
J.Mol.Biol., 401, 2010
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3KRA
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium | | Descriptor: | 1,2-ETHANEDIOL, Geranyl diphosphate synthase large subunit, Geranyl diphosphate synthase small subunit, ... | | Authors: | Chang, T.-H, Ko, T.-P, Hsieh, F.-L, Wang, A.H.-J. | | Deposit date: | 2009-11-18 | | Release date: | 2010-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3KRO
 | | Mint heterotetrameric geranyl pyrophosphate synthase in complex with magnesium, IPP, and DMASPP (II) | | Descriptor: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... | | Authors: | Chang, T.-H, Hsieh, F.-L, Ko, T.-P, Wang, A.H.-J. | | Deposit date: | 2009-11-19 | | Release date: | 2010-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
Plant Cell, 22, 2010
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3LCL
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2ZX9
 | | alpha-L-fucosidase complexed with inhibitor, B4 | | Descriptor: | (2S)-2-cyclopentyl-2-phenyl-N-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methylpiperidin-2-yl]methyl}ethanamide, Alpha-L-fucosidase, putative | | Authors: | Wu, H.-J, Ko, T.-P, Ho, C.-W, Lin, C.-H, Wang, A.H.-J. | | Deposit date: | 2008-12-22 | | Release date: | 2009-12-08 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | Structural basis of alpha-fucosidase inhibition by iminocyclitols with K(i) values in the micro- to picomolar range.
Angew.Chem.Int.Ed.Engl., 49, 2010
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