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PDB: 29 件
3KBP
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BU of 3kbp by Molmil
KIDNEY BEAN PURPLE ACID PHOSPHATASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FE (III) ION, PURPLE ACID PHOSPHATASE, ...
著者Klabunde, T, Strater, N, Krebs, B.
登録日1995-10-02
公開日1996-12-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanism of Fe(III)-Zn(II) purple acid phosphatase based on crystal structures.
J.Mol.Biol., 259, 1996
4KBP
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BU of 4kbp by Molmil
KIDNEY BEAN PURPLE ACID PHOSPHATASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FE (III) ION, PHOSPHATE ION, ...
著者Klabunde, T, Strater, N, Krebs, B.
登録日1995-10-02
公開日1996-12-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism of Fe(III)-Zn(II) purple acid phosphatase based on crystal structures.
J.Mol.Biol., 259, 1996
1KBP
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BU of 1kbp by Molmil
KIDNEY BEAN PURPLE ACID PHOSPHATASE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FE (III) ION, PURPLE ACID PHOSPHATASE, ...
著者Klabunde, T, Strater, N, Krebs, B.
登録日1995-02-20
公開日1996-10-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Mechanism of Fe(III)-Zn(II) purple acid phosphatase based on crystal structures.
J.Mol.Biol., 259, 1996
2ATI
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BU of 2ati by Molmil
Glycogen Phosphorylase Inhibitors
分子名称: Glycogen phosphorylase, liver form, N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA, ...
著者Klabunde, T, Wendt, K.U, Kadereit, D, Brachvogel, V, Burger, H.J, Herling, A.W, Oikonomakos, N.G, Schmoll, D, Sarubbi, E, von Roedern, E, Schoenafinger, K, Defossa, E.
登録日2005-08-25
公開日2006-08-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes.
J.Med.Chem., 48, 2005
1WUT
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BU of 1wut by Molmil
Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes
分子名称: 7-[2,6-DICHLORO-4-({[(2-CHLOROBENZOYL)AMINO]CARBONYL}AMINO)PHENOXY]HEPTANOIC ACID, Glycogen phosphorylase, muscle form, ...
著者Klabunde, T, Wendt, K.U, Kadereit, D, Brachvogel, V, Burger, H.-J, Herling, A.W, Oikonomakos, N.G, Kosmopoulou, M.N, Schmoll, D, Sarubbi, E, von Roedern, E, Schonafinger, K, Defossa, E.
登録日2004-12-08
公開日2005-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs
Protein Sci., 14, 2005
1BM7
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BU of 1bm7 by Molmil
HUMAN TRANSTHYRETIN (PREALBUMIN) COMPLEX WITH FLUFENAMIC ACID (2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID)
分子名称: 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, PROTEIN (TRANSTHYRETIN)
著者Klabunde, T, Kelly, J.W, Sacchettini, J.C.
登録日1998-07-29
公開日1998-08-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inhibiting transthyretin conformational changes that lead to amyloid fibril formation.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BT3
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BU of 1bt3 by Molmil
CATECHOL OXIDASE FROM IPOMOEA BATATAS (SWEET POTATOES) IN THE NATIVE CU(II)-CU(II) STATE
分子名称: CU-O-CU LINKAGE, PROTEIN (CATECHOL OXIDASE)
著者Klabunde, T, Eicken, C, Sacchettini, J.C, Krebs, B.
登録日1998-09-02
公開日1999-09-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a plant catechol oxidase containing a dicopper center.
Nat.Struct.Biol., 5, 1998
1BUG
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BU of 1bug by Molmil
CATECHOL OXIDASE FROM IPOMOEA BATATAS (SWEET POTATOES)-INHIBITOR COMPLEX WITH PHENYLTHIOUREA (PTU)
分子名称: COPPER (II) ION, N-PHENYLTHIOUREA, PROTEIN (CATECHOL OXIDASE)
著者Klabunde, T, Eicken, C, Sacchettini, J.C, Krebs, B.
登録日1998-09-03
公開日1999-09-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a plant catechol oxidase containing a dicopper center.
Nat.Struct.Biol., 5, 1998
1BT2
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CATECHOL OXIDASE FROM IPOMOEA BATATAS (SWEET POTATOES) IN THE REDUCED CU(I)-CU(I) STATE
分子名称: CU-O-CU LINKAGE, PROTEIN (CATECHOL OXIDASE)
著者Klabunde, T, Eicken, C, Sacchettini, J.C, Krebs, B.
登録日1998-09-02
公開日1999-09-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a plant catechol oxidase containing a dicopper center.
Nat.Struct.Biol., 5, 1998
1BMZ
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HUMAN TRANSTHYRETIN (PREALBUMIN)
分子名称: PROTEIN (TRANSTHYRETIN)
著者Klabunde, T, Kelly, J.W, Sacchettini, J.C.
登録日1998-07-27
公開日1998-08-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inhibiting transthyretin conformational changes that lead to amyloid fibril formation.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BT1
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BU of 1bt1 by Molmil
CATECHOL OXIDASE FROM IPOMOEA BATATAS (SWEET POTATOES) IN THE NATIVE CU(II)-CU(II) STATE
分子名称: CU-O-CU LINKAGE, PROTEIN (CATECHOL OXIDASE)
著者Klabunde, T, Eicken, C, Sacchettini, J.C, Krebs, B.
登録日1998-09-02
公開日1999-09-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a plant catechol oxidase containing a dicopper center.
Nat.Struct.Biol., 5, 1998
1AM2
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BU of 1am2 by Molmil
GYRA INTEIN FROM MYCOBACTERIUM XENOPI
分子名称: MXE GYRA INTEIN
著者Klabunde, T, Sharma, S, Sacchettini, J.C.
登録日1997-06-20
公開日1998-06-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing.
Nat.Struct.Biol., 5, 1998
1DVT
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BU of 1dvt by Molmil
CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH FLURBIPROFEN
分子名称: FLURBIPROFEN, TRANSTHYRETIN
著者Klabunde, T, Petrassi, H.M, Oza, V.B, Kelly, J.W, Sacchettini, J.C.
登録日2000-01-22
公開日2001-01-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVY
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BU of 1dvy by Molmil
CRYSTAL STRUCTURE OF TRANSTHYRETIN IN COMPLEX WITH N-(M-TRIFLUOROMETHYLPHENYL) PHENOXAZINE-4,6-DICARBOXYLIC ACID
分子名称: N-(M-TRIFLUOROMETHYLPHENYL) PHENOXAZINE-4,6-DICARBOXYLIC ACID, TRANSTHYRETIN
著者Klabunde, T, Petrassi, H.M, Oza, V.B, Kelly, J.W, Sacchettini, J.C.
登録日2000-01-23
公開日2001-01-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVU
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BU of 1dvu by Molmil
CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH DIBENZOFURAN-4,6-DICARBOXYLIC ACID
分子名称: DIBENZOFURAN-4,6-DICARBOXYLIC ACID, TRANSTHYRETIN
著者Klabunde, T, Petrassi, H.M, Oza, V.B, Kelly, J.W, Sacchettini, J.C.
登録日2000-01-22
公開日2001-01-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVX
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CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH DICLOFENAC
分子名称: 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, TRANSTHYRETIN
著者Klabunde, T, Petrassi, H.M, Oza, V.B, Kelly, J.W, Sacchettini, J.C.
登録日2000-01-23
公開日2001-01-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVZ
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BU of 1dvz by Molmil
CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH O-TRIFLUOROMETHYLPHENYL ANTHRANILIC ACID
分子名称: O-TRIFLUOROMETHYLPHENYL ANTHRANILIC ACID, TRANSTHYRETIN
著者Klabunde, T, Petrassi, H.M, Oza, V.B, Kelly, J.W, Sacchettini, J.C.
登録日2000-01-23
公開日2001-01-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVQ
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BU of 1dvq by Molmil
CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN
分子名称: TRANSTHYRETIN
著者Klabunde, T, Petrassi, H.M, Oza, V.B, Kelly, J.W, Sacchettini, J.C.
登録日2000-01-22
公開日2001-01-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1DVS
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BU of 1dvs by Molmil
CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH RESVERATROL
分子名称: RESVERATROL, TRANSTHYRETIN
著者Klabunde, T, Petrassi, H.M, Oza, V.B, Kelly, J.W, Sacchettini, J.C.
登録日2000-01-22
公開日2001-01-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Rational design of potent human transthyretin amyloid disease inhibitors.
Nat.Struct.Biol., 7, 2000
1G5Z
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BU of 1g5z by Molmil
CRYSTAL STRUCTURE OF LYME DISEASE ANTIGEN OUTER SURFACE PROTEIN C (OSPC) FROM BORRELIA BURGDORFERI STRAIN N40
分子名称: OUTER SURFACE PROTEIN C
著者Eicken, C, Sharma, V, Klabunde, T, Owens, R.T, Pikas, D.S, Hook, M, Sacchettini, J.C.
登録日2000-11-02
公開日2001-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal structure of Lyme disease antigen outer surface protein C from Borrelia burgdorferi.
J.Biol.Chem., 276, 2001
1WV0
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BU of 1wv0 by Molmil
Crystallographic studies on acyl ureas, a new class of inhibitors of glycogen phosphorylase. Broad specificity of the allosteric site
分子名称: 4-[4-({[(2,4-DICHLOROBENZOYL)AMINO]CARBONYL}AMINO)-2,3-DIMETHYLPHENOXY]BUTANOIC ACID, Glycogen phosphorylase, muscle form, ...
著者Oikonomakos, N.G, Kosmopoulou, M.N, Chrysina, E.D, Leonidas, D.D, Klabunde, T, Wendt, K.U, Defossa, E.
登録日2004-12-10
公開日2005-12-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs
Protein Sci., 14, 2005
1WV1
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Crystallographic studies on acyl ureas, a new class of inhibitors of glycogenphosphorylase. Broad specificity of the allosteric site
分子名称: 5-[3-({[(2,4-DICHLOROBENZOYL)AMINO]CARBONYL}AMINO)-2-METHYLPHENOXY]PENTANOIC ACID, Glycogen phosphorylase, muscle form, ...
著者Oikonomakos, N.G, Kosmopoulou, M.N, Chrysina, E.D, Leonidas, D.D, Klabunde, T, Wendt, K.U, Defossa, E.
登録日2004-12-10
公開日2005-12-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs
Protein Sci., 14, 2005
1WUY
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BU of 1wuy by Molmil
Crystallographic studies on acyl ureas, a new class of inhibitors of glycogen phosphorylase. Broad specificity of the allosteric site
分子名称: 4-[3-CHLORO-4-({[(2,4-DICHLOROBENZOYL)AMINO]CARBONYL}AMINO)PHENOXY]BUTANOIC ACID, Glycogen phosphorylase, muscle form, ...
著者Oikonomakos, N.G, Kosmopoulou, M.N, Chrysina, E.D, Leonidas, D.D, Klabunde, T, Wendt, K.U, Defossa, E.
登録日2004-12-09
公開日2005-12-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs
Protein Sci., 14, 2005
1L8W
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BU of 1l8w by Molmil
Crystal Structure of Lyme Disease Variable Surface Antigen VlsE of Borrelia burgdorferi
分子名称: VlsE1
著者Eicken, C, Sharma, V, Klabunde, T, Lawrenz, M.B, Hardham, J.M, Norris, S.J, Sacchettini, J.C.
登録日2002-03-21
公開日2002-06-19
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of Lyme disease variable surface antigen VlsE of Borrelia burgdorferi.
J.Biol.Chem., 277, 2002
3CEJ
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BU of 3cej by Molmil
Human glycogen phosphorylase (tense state) in complex with the allosteric inhibitor AVE2865
分子名称: 1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid, Glycogen phosphorylase, liver form, ...
著者Wendt, K.U, Dreyer, M.K, Anderka, O, Klabunde, T, Loenze, P, Defossa, E, Schmoll, D.
登録日2008-02-29
公開日2008-05-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Thermodynamic characterization of allosteric glycogen phosphorylase inhibitors.
Biochemistry, 47, 2008

 

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