1BM7

HUMAN TRANSTHYRETIN (PREALBUMIN) COMPLEX WITH FLUFENAMIC ACID (2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID)

Summary for 1BM7
DescriptorPROTEIN (TRANSTHYRETIN), 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID (3 entities in total)
Functional Keywordsthyroxine transport, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P02766
Total number of polymer chains2
Total formula weight28117.18
Authors
Klabunde, T.,Kelly, J.W.,Sacchettini, J.C. (deposition date: 1998-07-29, release date: 1998-08-05, Last modification date: 2011-07-13)
Primary citationKelly, J.W.,Klabunde, T.,Lashuel, H.A.,Peterson, S.A.,Purkey, H.,Sacchettini, J.C.
Inhibiting transthyretin conformational changes that lead to amyloid fibril formation.
Proc.Natl.Acad.Sci.USA, 95:12956-12960, 1998
PubMed: 9789022
DOI: 110.1073/pnas.95.22.12956
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation
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PDB entries from 2021-06-09