1DVZ

CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH O-TRIFLUOROMETHYLPHENYL ANTHRANILIC ACID

Summary for 1DVZ

Entry DOI	10.2210/pdb1dvz/pdb
Related	1BMZ 1DVQ 1DVS 1DVT 1DVU 1DVX 1DVY
Descriptor	TRANSTHYRETIN, O-TRIFLUOROMETHYLPHENYL ANTHRANILIC ACID (3 entities in total)
Functional Keywords	thyroxine transport, signaling protein, hormone-growth factor complex, hormone/growth factor
Biological source	Homo sapiens (human)
Cellular location	Secreted: P02766
Total number of polymer chains	2
Total formula weight	27123.17
Authors	Klabunde, T.,Petrassi, H.M.,Oza, V.B.,Kelly, J.W.,Sacchettini, J.C. (deposition date: 2000-01-23, release date: 2001-01-23, Last modification date: 2024-02-07)
Primary citation	Klabunde, T.,Petrassi, H.M.,Oza, V.B.,Raman, P.,Kelly, J.W.,Sacchettini, J.C. Rational design of potent human transthyretin amyloid disease inhibitors. Nat.Struct.Biol., 7:312-321, 2000 Cited by PubMed: 10742177 DOI: 10.1038/74082 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation