1GCM
 
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2EBO
 | | CORE STRUCTURE OF GP2 FROM EBOLA VIRUS | | 分子名称: | CHLORIDE ION, EBOLA VIRUS ENVELOPE GLYCOPROTEIN | | 著者 | Malashkevich, V.N, Schneider, B.J, Mcnally, M.L, Milhollen, M.A, Pang, J.X, Kim, P.S. | | 登録日 | 1998-12-24 | | 公開日 | 1999-05-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-A resolution.
Proc.Natl.Acad.Sci.USA, 96, 1999
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6UMV
 | | Human apo PD-1 double mutant | | 分子名称: | CHLORIDE ION, Programmed cell death protein 1 | | 著者 | Tang, S, Kim, P.S. | | 登録日 | 2019-10-10 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.424 Å) | | 主引用文献 | A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6UMT
 | | High-affinity human PD-1 PD-L2 complex | | 分子名称: | MAGNESIUM ION, Programmed cell death 1 ligand 2, Programmed cell death protein 1 | | 著者 | Tang, S, Kim, P.S. | | 登録日 | 2019-10-10 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.986 Å) | | 主引用文献 | A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6UMU
 | | Human apo PD-1 triple mutant | | 分子名称: | CHLORIDE ION, Programmed cell death protein 1 | | 著者 | Tang, S, Kim, P.S. | | 登録日 | 2019-10-10 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.183 Å) | | 主引用文献 | A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery.
Proc.Natl.Acad.Sci.USA, 116, 2019
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1GCL
 | | GCN4 LEUCINE ZIPPER CORE MUTANT P-LI | | 分子名称: | GCN4 | | 著者 | Harbury, P.B, Zhang, T, Kim, P.S, Alber, T. | | 登録日 | 1993-10-20 | | 公開日 | 1995-06-03 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants.
Science, 262, 1993
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2SIV
 | | SIV GP41 CORE STRUCTURE | | 分子名称: | SIV GP41 GLYCOPROTEIN | | 著者 | Malashkevich, V.N, Chan, D.C, Chutkowski, C.T, Kim, P.S. | | 登録日 | 1998-06-17 | | 公開日 | 1998-08-19 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of the simian immunodeficiency virus (SIV) gp41 core: conserved helical interactions underlie the broad inhibitory activity of gp41 peptides.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1G2C
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1GZL
 | | Crystal structure of C14linkmid/IQN17: a cross-linked inhibitor of HIV-1 entry bound to the gp41 hydrophobic pocket | | 分子名称: | CHLORIDE ION, ENVELOPE GLYCOPROTEIN GP41, FUSION PROTEIN BETWEEN THE HYDROPHOBIC POCKET OF HIV GP41 AND GENERAL CONTROL PROTEIN GCN4-PIQI, ... | | 著者 | Sia, S.K, Carr, P.A, Cochran, A.G, Malashkevich, V.M, Kim, P.S. | | 登録日 | 2002-05-23 | | 公開日 | 2002-10-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Short Constrained Peptides that Inhibit HIV-1 Entry
Proc.Natl.Acad.Sci.USA, 99, 2002
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2Q7C
 | | Crystal structure of IQN17 | | 分子名称: | CHLORIDE ION, fusion protein between yeast variant GCN4 and HIVgp41 | | 著者 | Malashkevich, V.N, Eckert, D.M, Hong, L.H, Kim, P.S. | | 登録日 | 2007-06-06 | | 公開日 | 2007-06-19 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Inhibiting HIV Entry: Discovery of D-Peptide Inhibitors that Target the Gp41 Coiled-Coil Pocket
Cell(Cambridge,Mass.), 99, 1999
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2Q5U
 | | Crystal structure of IQN17 | | 分子名称: | CHLORIDE ION, Fusion protein between yeast variant GCN4 and HIVgp41 | | 著者 | Malashkevich, V.N, Eckert, D.M, Hong, L.H, Kim, P.S. | | 登録日 | 2007-06-01 | | 公開日 | 2007-06-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Inhibiting HIV Entry: Discovery of D-Peptide Inhibitors that Target the Gp41 Coiled-Coil Pocket
Cell(Cambridge,Mass.), 99, 1999
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2Q3I
 | | Crystal structure of the D10-P3/IQN17 complex: a D-peptide inhibitor of HIV-1 entry bound to the GP41 coiled-coil pocket | | 分子名称: | CHLORIDE ION, D-peptide, Fusion protein between the Coiled-Coil pocket of HIV GP41 and gcn4-PIQI | | 著者 | Malashkevich, V.N, Eckert, D.M, Hong, L.H, Carr, P.A, Kim, P.S. | | 登録日 | 2007-05-30 | | 公開日 | 2007-06-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Inhibiting HIV Entry: Discovery of D-Peptide Inhibitors that Target the Gp41 Coiled-Coil Pocket
Cell(Cambridge,Mass.), 99, 1999
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2ZTA
 | | X-RAY STRUCTURE OF THE GCN4 LEUCINE ZIPPER, A TWO-STRANDED, PARALLEL COILED COIL | | 分子名称: | GCN4 LEUCINE ZIPPER | | 著者 | O'Shea, E.K, Klemm, J.D, Kim, P.S, Alber, T. | | 登録日 | 1991-07-05 | | 公開日 | 1992-10-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil.
Science, 254, 1991
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1AJJ
 | | LDL RECEPTOR LIGAND-BINDING MODULE 5, CALCIUM-COORDINATING | | 分子名称: | CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR, SULFATE ION | | 著者 | Fass, D, Blacklow, S.C, Kim, P.S, Berger, J.M. | | 登録日 | 1997-05-04 | | 公開日 | 1997-07-07 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module.
Nature, 388, 1997
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1JEK
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1IJ1
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1AOL
 | | FRIEND MURINE LEUKEMIA VIRUS RECEPTOR-BINDING DOMAIN | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GP70, ZINC ION | | 著者 | Fass, D, Davey, R.A, Hamson, C.A, Kim, P.S, Cunningham, J.M, Berger, J.M. | | 登録日 | 1997-07-08 | | 公開日 | 1997-10-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution.
Science, 277, 1997
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1AIK
 | | HIV GP41 CORE STRUCTURE | | 分子名称: | HIV-1 GP41 GLYCOPROTEIN | | 著者 | Chan, D.C, Fass, D, Berger, J.M, Kim, P.S. | | 登録日 | 1997-04-20 | | 公開日 | 1997-06-16 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Core structure of gp41 from the HIV envelope glycoprotein.
Cell(Cambridge,Mass.), 89, 1997
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1CZQ
 | | CRYSTAL STRUCTURE OF THE D10-P1/IQN17 COMPLEX: A D-PEPTIDE INHIBITOR OF HIV-1 ENTRY BOUND TO THE GP41 COILED-COIL POCKET. | | 分子名称: | CHLORIDE ION, D-PEPTIDE INHIBITOR, FUSION PROTEIN BETWEEN THE HYDROPHOBIC POCKET OF HIV GP41 AND GCN4-PIQI | | 著者 | Eckert, D.M, Malashkevich, V.N, Hong, L.H, Carr, P.A, Kim, P.S. | | 登録日 | 1999-09-06 | | 公開日 | 1999-10-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket.
Cell(Cambridge,Mass.), 99, 1999
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8F3A
 | | HIV-1 gp41 coiled-coil pocket IQN17 | | 分子名称: | ACETIC ACID, CHLORIDE ION, IQN17 | | 著者 | Bruun, T.U.J, Tang, S, Fernandez, D, Kim, P.S. | | 登録日 | 2022-11-09 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structure-guided stabilization improves the ability of the HIV-1 gp41 hydrophobic pocket to elicit neutralizing antibodies.
J.Biol.Chem., 299, 2023
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8F3B
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1PIQ
 | | CRYSTAL STRUCTURE OF GCN4-PIQ, A TRIMERIC COILED COIL WITH BURIED POLAR RESIDUES | | 分子名称: | CHLORIDE ION, PROTEIN (GENERAL CONTROL PROTEIN GCN4-PIQ) | | 著者 | Eckert, D.M, Malashkevich, V.N, Kim, P.S. | | 登録日 | 1998-09-25 | | 公開日 | 1998-09-30 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of GCN4-pIQI, a trimeric coiled coil with buried polar residues.
J.Mol.Biol., 284, 1998
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7UX0
 | | Human Sperm TMEM95 Ectodomain | | 分子名称: | Sperm-egg fusion protein TMEM95, TRIETHYLENE GLYCOL, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Tang, S, Kim, P.S. | | 登録日 | 2022-05-04 | | 公開日 | 2022-10-12 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Human sperm TMEM95 binds eggs and facilitates membrane fusion.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1TGG
 | | RH3 DESIGNED RIGHT-HANDED COILED COIL TRIMER | | 分子名称: | CHLORIDE ION, NICKEL (II) ION, right-handed coiled coil trimer | | 著者 | Plecs, J.J, Harbury, P.B, Kim, P.S, Alber, T. | | 登録日 | 2004-05-28 | | 公開日 | 2004-10-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural test of the parameterized-backbone method for protein design
J.Mol.Biol., 342, 2004
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1IJ3
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