1CZQ

CRYSTAL STRUCTURE OF THE D10-P1/IQN17 COMPLEX: A D-PEPTIDE INHIBITOR OF HIV-1 ENTRY BOUND TO THE GP41 COILED-COIL POCKET.

Summary for 1CZQ

Entry DOI	10.2210/pdb1czq/pdb
Descriptor	FUSION PROTEIN BETWEEN THE HYDROPHOBIC POCKET OF HIV GP41 AND GCN4-PIQI, D-PEPTIDE INHIBITOR, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	envelope glycoprotein, viral protein-inhibitor complex, viral protein/inhibitor
Biological source	Saccharomyces cerevisiae, Human immunodeficiency virus (baker's yeast,) More
Total number of polymer chains	2
Total formula weight	7363.14
Authors	Eckert, D.M.,Malashkevich, V.N.,Hong, L.H.,Carr, P.A.,Kim, P.S. (deposition date: 1999-09-06, release date: 1999-10-13, Last modification date: 2011-07-13)
Primary citation	Eckert, D.M.,Malashkevich, V.N.,Hong, L.H.,Carr, P.A.,Kim, P.S. Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket. Cell(Cambridge,Mass.), 99:103-115, 1999 Cited by PubMed: 10520998 DOI: 10.1016/S0092-8674(00)80066-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation