4DXM
 
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4DXI
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4DXN
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4DXO
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4GOB
 | | Low pH Crystal Structure of a reconstructed Kaede-type Red Fluorescent Protein, Least Evolved Ancestor (LEA) | | Descriptor: | Kaede-type Fluorescent Protein | | Authors: | Kim, H, Grunkemeyer, T.J, Chen, L, Fromme, R, Wachter, R.M. | | Deposit date: | 2012-08-19 | | Release date: | 2013-07-31 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Acid-base catalysis and crystal structures of a least evolved ancestral GFP-like protein undergoing green-to-red photoconversion.
Biochemistry, 52, 2013
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1ZDR
 | | DHFR from Bacillus Stearothermophilus | | Descriptor: | GLYCEROL, SULFATE ION, dihydrofolate reductase | | Authors: | Kim, H.S, Damo, S.M, Lee, S.Y, Wemmer, D, Klinman, J.P. | | Deposit date: | 2005-04-14 | | Release date: | 2005-08-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure and hydride transfer mechanism of a moderate thermophilic dihydrofolate reductase from Bacillus stearothermophilus and comparison to its mesophilic and hyperthermophilic homologues.
Biochemistry, 44, 2005
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1J32
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7VWX
 | | CryoEM structure of football-shaped GroEL:ES2 with RuBisCO | | Descriptor: | Chaperonin GroEL, Co-chaperonin GroES, Ribulose bisphosphate carboxylase | | Authors: | Kim, H, Roh, S.H. | | Deposit date: | 2021-11-12 | | Release date: | 2022-01-12 | | Last modified: | 2024-06-26 | | Method: | ELECTRON MICROSCOPY (7.6 Å) | | Cite: | Cryo-EM structures of GroEL:ES 2 with RuBisCO visualize molecular contacts of encapsulated substrates in a double-cage chaperonin.
Iscience, 25, 2022
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2MSY
 | | Solution structure of Hox homeodomain | | Descriptor: | Homeobox protein Hox-C9 | | Authors: | Kim, H, Park, S, Han, J, Lee, B. | | Deposit date: | 2014-08-11 | | Release date: | 2015-09-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural insight into the interaction between the Hox and HMGB1 and understanding of the HMGB1-enhancing effect of Hox-DNA binding.
Biochim.Biophys.Acta, 1854, 2015
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7X15
 | | Crystal structure of MIGA2 LD targeting domain | | Descriptor: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, FORMIC ACID, Mitoguardin 2 | | Authors: | Kim, H, Lee, C. | | Deposit date: | 2022-02-23 | | Release date: | 2022-09-14 | | Method: | X-RAY DIFFRACTION (2.852 Å) | | Cite: | Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites.
Nat Commun, 13, 2022
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7X14
 | | Crystal structure of phospho-FFAT motif of MIGA2 bound to VAPB | | Descriptor: | MIGA2 phospho FFAT motif, SULFATE ION, Vesicle-associated membrane protein-associated protein B | | Authors: | Kim, H, Lee, C. | | Deposit date: | 2022-02-23 | | Release date: | 2022-09-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.675 Å) | | Cite: | Structural basis for mitoguardin-2 mediated lipid transport at ER-mitochondrial membrane contact sites.
Nat Commun, 13, 2022
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4Q2Y
 | | Crystal structure of Arginyl-tRNA synthetase | | Descriptor: | Arginine--tRNA ligase, cytoplasmic | | Authors: | Kim, H.S, Jo, C.H, Cha, S.Y, Han, A.R, Hwang, K.Y. | | Deposit date: | 2014-04-10 | | Release date: | 2014-07-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.799 Å) | | Cite: | The crystal structure of arginyl-tRNA synthetase from Homo sapiens
Febs Lett., 588, 2014
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4Q2T
 | | Crystal structure of Arginyl-tRNA synthetase complexed with L-arginine | | Descriptor: | ARGININE, Arginine--tRNA ligase, cytoplasmic, ... | | Authors: | Kim, H.S, Jo, C.H, Cha, S.Y, Han, A.R, Hwang, K.Y. | | Deposit date: | 2014-04-09 | | Release date: | 2014-07-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The crystal structure of arginyl-tRNA synthetase from Homo sapiens
Febs Lett., 588, 2014
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4Q2X
 | | Crystal structure of Arginyl-tRNA synthetase complexed with L-canavanine | | Descriptor: | Arginine--tRNA ligase, cytoplasmic, L-CANAVANINE | | Authors: | Kim, H.S, Jo, C.H, Cha, S.Y, Han, A.R, Hwang, K.Y. | | Deposit date: | 2014-04-10 | | Release date: | 2014-07-23 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.798 Å) | | Cite: | The crystal structure of arginyl-tRNA synthetase from Homo sapiens
Febs Lett., 588, 2014
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5X90
 | | Structure of DotL(656-783)-IcmS-IcmW-LvgA derived from Legionella pneumophila | | Descriptor: | Hypothetical virulence protein, IcmO (DotL), IcmS, ... | | Authors: | Kim, H, Kwak, M.J, Kim, J.D, Kim, Y.G, Oh, B.H. | | Deposit date: | 2017-03-04 | | Release date: | 2017-06-14 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Architecture of the type IV coupling protein complex of Legionella pneumophila
Nat Microbiol, 2, 2017
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3OUH
 | | PHD2-R127 with JNJ41536014 | | Descriptor: | 1-(5-chloro-6-fluoro-1H-benzimidazol-2-yl)-1H-pyrazole-4-carboxylic acid, Egl nine homolog 1, FE (II) ION, ... | | Authors: | Kim, H, Clark, R. | | Deposit date: | 2010-09-14 | | Release date: | 2010-12-01 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues.
ACS Med Chem Lett, 1, 2010
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8HEJ
 | | Crystal structure of Transthyretin in complex with a covalent inhibitor trans-styrylpyrazole | | Descriptor: | 2,4,6-trifluorobenzaldehyde, 2,6-dibromo-4-[(E)-2-(3,5-dimethyl-1H-pyrazol-4-yl)ethenyl]phenol, Transthyretin | | Authors: | Kim, H, Choi, S, Lee, C. | | Deposit date: | 2022-11-08 | | Release date: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Crystal structure of Transthyretin in complex with a covalent inhibitor trans-styrylpyrazole
To Be Published
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8KHO
 | | Crystal structure of human methionine aminopeptidase 12 (MAP12) in complex with two Cobalt ions and Methionine | | Descriptor: | COBALT (II) ION, METHIONINE, Methionine aminopeptidase 1D, ... | | Authors: | Lee, Y, Lee, E, Hahn, H, Kim, H, Heo, Y, Jang, D.M, Kim, H.J, Kim, H.S. | | Deposit date: | 2023-08-22 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D.
Sci Rep, 13, 2023
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8KHN
 | | Crystal structure of human methionine aminopeptidase 12 (MAP12) in complex with two cobalt ions | | Descriptor: | COBALT (II) ION, Methionine aminopeptidase 1D, mitochondrial, ... | | Authors: | Lee, Y, Lee, E, Hahn, H, Kim, H, Heo, Y, Jang, D.M, Kim, H.J, Kim, H.S. | | Deposit date: | 2023-08-22 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D.
Sci Rep, 13, 2023
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8KHM
 | | Crystal structure of human methionine aminopeptidase 12 (MAP12) in the unbound form | | Descriptor: | GLYCEROL, Methionine aminopeptidase 1D, mitochondrial, ... | | Authors: | Lee, Y, Lee, E, Hahn, H, Kim, H, Heo, Y, Jang, D.M, Kim, H.J, Kim, H.S. | | Deposit date: | 2023-08-22 | | Release date: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.39 Å) | | Cite: | Structural insights into N-terminal methionine cleavage by the human mitochondrial methionine aminopeptidase, MetAP1D.
Sci Rep, 13, 2023
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2QHU
 | | Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B | | Descriptor: | Lipoyltransferase, OCTANAL | | Authors: | Kim, D.J, Lee, S.J, Kim, H.S, Kim, K.H, Lee, H.H, Yoon, H.J, Suh, S.W. | | Deposit date: | 2007-07-02 | | Release date: | 2008-02-26 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis of octanoic acid recognition by lipoate-protein ligase B
Proteins, 70, 2008
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8GTG
 | | Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-I-152 by XFEL | | Descriptor: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N},~{N}-bis(2-methoxyethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | | Authors: | Cho, H.S, Kim, H. | | Deposit date: | 2022-09-08 | | Release date: | 2023-09-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Exp.Mol.Med., 55, 2023
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8GTI
 | | Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C205 by XFEL | | Descriptor: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N}-butyl-~{N}-(cyclopropylmethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1, ... | | Authors: | Cho, H.S, Kim, H. | | Deposit date: | 2022-09-08 | | Release date: | 2023-09-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Exp.Mol.Med., 55, 2023
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8GTM
 | | Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C203 by XFEL | | Descriptor: | 7-(4-bromanyl-2,6-dimethoxy-phenyl)-4,8-dimethyl-~{N},~{N}-bis[4,4,4-tris(fluoranyl)butyl]-1$l^{4},3,5,9-tetrazabicyclo[4.3.0]nona-1(6),2,4,8-tetraen-2-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | | Authors: | Cho, H.S, Kim, H. | | Deposit date: | 2022-09-08 | | Release date: | 2023-09-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Exp.Mol.Med., 55, 2023
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4FYB
 | | Structural and functional characterizations of a thioredoxin-fold protein from Helicobacter pylori | | Descriptor: | GLYCEROL, Thiol:disulfide interchange protein (DsbC) | | Authors: | Yoon, J.Y, Kim, J, Lee, S.J, Im, H.N, Kim, H.S, Yoon, H, An, D.R, Kim, J.Y, Kim, S, Han, B.W, Suh, S.W. | | Deposit date: | 2012-07-04 | | Release date: | 2013-05-08 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural and functional characterization of HP0377, a thioredoxin-fold protein from Helicobacter pylori
Acta Crystallogr.,Sect.D, 69, 2013
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