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PDB: 50 results

4L4X
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BU of 4l4x by Molmil
An A2-type ketoreductase from a modular polyketide synthase
Descriptor: AmphI, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, J, Keatinge-Clay, A.T.
Deposit date:2013-06-10
Release date:2013-06-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Studies of an A2-Type Modular Polyketide Synthase Ketoreductase Reveal Features Controlling alpha-Substituent Stereochemistry.
Acs Chem.Biol., 8, 2013
3SLK
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BU of 3slk by Molmil
Structure of ketoreductase and enoylreductase didomain from modular polyketide synthase
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Polyketide synthase extender module 2, SULFATE ION
Authors:Zheng, J, Gay, D.C, Keatinge-Clay, A.T.
Deposit date:2011-06-24
Release date:2012-05-30
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Divergence of multimodular polyketide synthases revealed by a didomain structure.
Nat.Chem.Biol., 8, 2012
3UYL
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BU of 3uyl by Molmil
Spinosyn Rhamnosyltransferase SpnG complexed with thymidine diphosphate
Descriptor: MAGNESIUM ION, NDP-rhamnosyltransferase, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T.
Deposit date:2011-12-06
Release date:2012-02-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG.
Biochemistry, 51, 2012
3UYK
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Spinosyn Rhamnosyltransferase SpnG complexed with spinosyn aglycone
Descriptor: (2R,3aS,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-2,13-dihydroxy-14-methyl-2,3,3a,5a,5b,6,9,10,11,12,13,14,16a,16b-tetradecahydro-1H-as-indaceno[3,2-d]oxacyclododecine-7,15-dione, MAGNESIUM ION, NDP-rhamnosyltransferase, ...
Authors:Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T.
Deposit date:2011-12-06
Release date:2012-02-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG.
Biochemistry, 51, 2012
3TSA
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BU of 3tsa by Molmil
Spinosyn Rhamnosyltransferase SpnG
Descriptor: MAGNESIUM ION, NDP-rhamnosyltransferase, alpha-D-glucopyranose
Authors:Isiorho, E.A, Liu, H.-W, Keatinge-Clay, A.T.
Deposit date:2011-09-12
Release date:2012-02-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Studies of the Spinosyn Rhamnosyltransferase, SpnG.
Biochemistry, 51, 2012
4OXI
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BU of 4oxi by Molmil
Crystal structure of Vibrio cholerae adenylation domain AlmE in complex with glycyl-adenosine-5'-phosphate
Descriptor: Enterobactin synthetase component F-related protein, GLYCYL-ADENOSINE-5'-PHOSPHATE
Authors:Fage, C.D, Henderson, J.C, Keatinge-Clay, A.T, Trent, M.S.
Deposit date:2014-02-05
Release date:2014-12-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.261 Å)
Cite:Antimicrobial peptide resistance of Vibrio cholerae results from an LPS modification pathway related to nonribosomal peptide synthetases.
Acs Chem.Biol., 9, 2014
4PNE
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BU of 4pne by Molmil
Crystal Structure of the [4+2]-Cyclase SpnF
Descriptor: MALONATE ION, Methyltransferase-like protein, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Fage, C.D, Isiorho, E.A, Liu, Y.-N, Liu, H.-W, Keatinge-Clay, A.T.
Deposit date:2014-05-23
Release date:2015-02-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structure of SpnF, a standalone enzyme that catalyzes [4 + 2] cycloaddition.
Nat.Chem.Biol., 11, 2015
3MJS
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BU of 3mjs by Molmil
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Descriptor: (2S)-2-hydroxybutanedioic acid, AmphB, D-MALATE, ...
Authors:Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
Deposit date:2010-04-13
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3MJV
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BU of 3mjv by Molmil
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Descriptor: AmphB, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
Deposit date:2010-04-13
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
4NA1
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BU of 4na1 by Molmil
Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase
Descriptor: Polyketide synthase PksJ, SULFATE ION
Authors:Gay, D.C, Gay, G.R, Keatinge-Clay, A.T.
Deposit date:2013-10-21
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.
Structure, 22, 2014
4NA2
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Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase bound to its natural intermediate
Descriptor: Polyketide synthase PksJ
Authors:Gay, D.C, Gay, G.R, Keatinge-Clay, A.T.
Deposit date:2013-10-21
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.
Structure, 22, 2014
4NA3
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BU of 4na3 by Molmil
Crystal Structure of the second ketosynthase from the bacillaene polyketide synthase bound to a hexanoyl substrate mimic
Descriptor: Polyketide synthase PksJ, SULFATE ION
Authors:Gay, D.C, Gay, G.R, Keatinge-Clay, A.T.
Deposit date:2013-10-21
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.
Structure, 22, 2014
3MJE
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BU of 3mje by Molmil
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Descriptor: AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
Deposit date:2010-04-12
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3MJT
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BU of 3mjt by Molmil
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Descriptor: AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
Deposit date:2010-04-13
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
3MJC
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BU of 3mjc by Molmil
Structure of A-type Ketoreductases from Modular Polyketide Synthase
Descriptor: AmphB, GLYCEROL
Authors:Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T.
Deposit date:2010-04-12
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
4QXL
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BU of 4qxl by Molmil
Crystal Structure of FLHE
Descriptor: Flagellar protein flhE
Authors:Lee, J, Monzingo, A.F, Keatinge-Clay, A.T, Harshey, R.M.
Deposit date:2014-07-21
Release date:2015-01-14
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.512 Å)
Cite:Structure of Salmonella FlhE, Conserved Member of a Flagellar Type III Secretion Operon.
J.Mol.Biol., 427, 2015
5E5N
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BU of 5e5n by Molmil
Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 (C167S mutant, crystal form 1)
Descriptor: Polyketide synthase PksL
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T.
Deposit date:2015-10-08
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
5E6K
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BU of 5e6k by Molmil
Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 (C167S mutant, crystal form 2)
Descriptor: Polyketide synthase PksL, SULFATE ION
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T.
Deposit date:2015-10-10
Release date:2015-11-18
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
5ELP
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BU of 5elp by Molmil
Ketosynthase from module 1 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42
Descriptor: NRPS/PKS protein
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T, Zogzas, C.E.
Deposit date:2015-11-04
Release date:2016-01-13
Last modified:2016-11-02
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
5ERF
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BU of 5erf by Molmil
Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168
Descriptor: Polyketide synthase PksL
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T.
Deposit date:2015-11-14
Release date:2015-12-23
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
5ENY
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BU of 5eny by Molmil
Ketosynthase from module 6 connected to acyl carrier protein from module 5 (unobservable) of the bacillaene synthase from Bacillus subtilis 168
Descriptor: Polyketide synthase PksL
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T.
Deposit date:2015-11-09
Release date:2015-12-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (4 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
5ERB
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BU of 5erb by Molmil
Ketosynthase from module 5 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42
Descriptor: Polyketide synthase
Authors:Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T, Meinke, J.
Deposit date:2015-11-13
Release date:2015-12-23
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.
J.Struct.Biol., 193, 2016
4LN9
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BU of 4ln9 by Molmil
Crystal structure of the dehydratase domain from the terminal module of the rifamycin polyketide synthase
Descriptor: Rifamycin polyketide synthase
Authors:Gay, D.C, You, Y.-O, Cane, D, Keatinge-Clay, A.T.
Deposit date:2013-07-11
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structure and stereospecificity of the dehydratase domain from the terminal module of the rifamycin polyketide synthase.
Biochemistry, 52, 2013
3NYR
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BU of 3nyr by Molmil
Malonyl-CoA Ligase Ternary Product Complex with Malonyl-CoA and AMP bound
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, MALONYL-COENZYME A, ...
Authors:Hughes, A.J, Keatinge-Clay, A.T.
Deposit date:2010-07-15
Release date:2011-03-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Enzymatic Extender Unit Generation for In Vitro Polyketide Synthase Reactions: Structural and Functional Showcasing of Streptomyces coelicolor MatB.
Chem.Biol., 18, 2011
3NYQ
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BU of 3nyq by Molmil
Malonyl-CoA Ligase Ternary Product Complex with Methylmalonyl-CoA and AMP bound
Descriptor: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hughes, A.J, Keatinge-Clay, A.T.
Deposit date:2010-07-15
Release date:2011-03-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Enzymatic Extender Unit Generation for In Vitro Polyketide Synthase Reactions: Structural and Functional Showcasing of Streptomyces coelicolor MatB.
Chem.Biol., 18, 2011
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