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4L4X

An A2-type ketoreductase from a modular polyketide synthase

Replaces:  4DI7
Summary for 4L4X
Entry DOI10.2210/pdb4l4x/pdb
Related2FR0 2Z5L 3MJS
DescriptorAmphI, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywordsrossmann fold, ketoreductase, oxidoreductase
Biological sourceStreptomyces nodosus
Total number of polymer chains1
Total formula weight62072.74
Authors
Zheng, J.,Keatinge-Clay, A.T. (deposition date: 2013-06-10, release date: 2013-06-19, Last modification date: 2023-09-20)
Primary citationZheng, J.,Piasecki, S.K.,Keatinge-Clay, A.T.
Structural Studies of an A2-Type Modular Polyketide Synthase Ketoreductase Reveal Features Controlling alpha-Substituent Stereochemistry.
Acs Chem.Biol., 8:1964-1971, 2013
Cited by
PubMed: 23755878
DOI: 10.1021/cb400161g
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.55 Å)
Structure validation

218853

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