4L4X

An A2-type ketoreductase from a modular polyketide synthase

Replaces:  4DI7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	AmphI	polymer	580	61327.3	1	UniProt (Q93NX9) Pfam (PF18369) Pfam (PF08659) In PDB	Streptomyces nodosus
2	A	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		745.4	1	Chemie (NDP)
3		water	water		18.0	6	Chemie (HOH)

Sequence modifications

A: 0 - 559 (UniProt: Q93NX9)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	61327.3
Non-Polymers*	Number of molecules	1
	Total formula weight	745.4
All*	Total formula weight	62072.7

*Water molecules are not included.