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PDB: 5 results

5JBT
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BU of 5jbt by Molmil
Mesotrypsin in complex with cleaved amyloid precursor like protein 2 inhibitor (APLP2)
Descriptor: Amyloid-like protein 2, CALCIUM ION, PRSS3 protein, ...
Authors:Kayode, O, Wang, R, Pendlebury, D, Soares, A, Radisky, E.S.
Deposit date:2016-04-13
Release date:2016-11-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis.
J. Biol. Chem., 291, 2016
5C67
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BU of 5c67 by Molmil
Human Mesotrypsin in complex with amyloid precursor protein inhibitor variant APPI-M17G/I18F/F34V
Descriptor: Amyloid beta A4 protein, Trypsin-3
Authors:Kayode, O, Sankaran, B, Radisky, E.S.
Deposit date:2015-06-22
Release date:2016-05-04
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy.
Biochem.J., 473, 2016
5TP0
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BU of 5tp0 by Molmil
Human mesotrypsin in complex with diminazene
Descriptor: BERENIL, CALCIUM ION, SULFATE ION, ...
Authors:Kayode, O, Soares, A, Radisky, E.S.
Deposit date:2016-10-19
Release date:2017-05-17
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Small molecule inhibitors of mesotrypsin from a structure-based docking screen.
PLoS ONE, 12, 2017
4WWY
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BU of 4wwy by Molmil
human cationic trypsin G193R mutant in complex with bovine pancreatic trypsin inhibitor
Descriptor: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ...
Authors:Alloy, A, Kayode, O, Soares, A.S, Wang, R, Radisky, E.S.
Deposit date:2014-11-12
Release date:2015-07-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates.
J.Biol.Chem., 290, 2015
4WXV
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BU of 4wxv by Molmil
Human cationic trypsin K97D mutant in complex with bovine pancreatic trypsin inhibitor (BPTI)
Descriptor: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ...
Authors:Alloy, A, Kayode, O, Soares, A.S, Wang, R, Radisky, E.S.
Deposit date:2014-11-14
Release date:2015-07-22
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as Substrates.
J.Biol.Chem., 290, 2015

226707

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