5TP0

Human mesotrypsin in complex with diminazene

Summary for 5TP0

Entry DOI	10.2210/pdb5tp0/pdb
Descriptor	Trypsin-3, CALCIUM ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	trypsin, serine-type endopeptidase, serine hydrolase, complex with small molecule drug, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	24979.10
Authors	Kayode, O.,Soares, A.,Radisky, E.S. (deposition date: 2016-10-19, release date: 2017-05-17, Last modification date: 2023-10-04)
Primary citation	Kayode, O.,Huang, Z.,Soares, A.S.,Caulfield, T.R.,Dong, Z.,Bode, A.M.,Radisky, E.S. Small molecule inhibitors of mesotrypsin from a structure-based docking screen. PLoS ONE, 12:e0176694-e0176694, 2017 Cited by PubMed: 28463992 DOI: 10.1371/journal.pone.0176694 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.25 Å)

Structure validation