1R38
 
 | | Crystal structure of H114A mutant of Candida tenuis xylose reductase | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, xylose reductase | | 著者 | Kratzer, R, Kavanagh, K.L, Wilson, D.K, Nidetzky, B. | | 登録日 | 2003-09-30 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant
Biochemistry, 43, 2004
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1SM9
 | | Crystal Structure Of An Engineered K274RN276D Double Mutant of Xylose Reductase From Candida Tenuis Optimized To Utilize NAD | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, xylose reductase | | 著者 | Petschacher, B, Leitgeb, S, Kavanagh, K.L, Wilson, D.K, Nidetzky, B. | | 登録日 | 2004-03-08 | | 公開日 | 2004-12-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography.
Biochem.J., 385, 2005
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2WUL
 | | CRYSTAL STRUCTURE OF THE HUMAN GLUTAREDOXIN 5 WITH BOUND GLUTATHIONE IN AN FES CLUSTER | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Roos, A.K, Johansson, C, Guo, K, Yue, W.W, Pike, A.C.W, Cooper, C.D.O, Pilka, E.S, Kavanagh, K.L, Chaikuad, A, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | | 登録日 | 2009-10-06 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The Crystal Structure of Human Glrx5: Iron Sulphur Cluster Coordination, Tetrameric Assembly and Monomer Activity.
Biochem.J., 433, 2011
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2X4D
 | | Crystal structure of human phospholysine phosphohistidine inorganic pyrophosphate phosphatase LHPP | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Vollmar, M, Gileadi, C, Guo, K, Savitsky, P, Muniz, J.R.C, Yue, W, Allerston, C, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Kavanagh, K.L, Oppermann, U. | | 登録日 | 2010-01-29 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Crystal Structure of Human Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase Lhpp
To be Published
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1ZSY
 | | The structure of human mitochondrial 2-enoyl thioester reductase (CGI-63) | | 分子名称: | GLYCEROL, MITOCHONDRIAL 2-ENOYL THIOESTER REDUCTASE, SULFATE ION | | 著者 | Lukacik, P, Shafqat, N, Kavanagh, K.L, Johansson, C, Smee, C, Edwards, A, Arrowsmith, C, Sundstrom, M, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2005-05-25 | | 公開日 | 2005-06-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The structure of human mitochondrial 2-enoyl thioester reductase (CGI-63)
To be Published
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2XDV
 | | Crystal Structure of the Catalytic Domain of FLJ14393 | | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, MANGANESE (II) ION, ... | | 著者 | Krojer, T, Muniz, J.R.C, Ng, S.S, Pilka, E, Guo, K, Pike, A.C.W, Filippakopoulos, P, Knapp, S, Kavanagh, K.L, Gileadi, O, Bunkoczi, G, Yue, W.W, Niesen, F, Sobott, F, Fedorov, O, Savitsky, P, Kochan, G, Daniel, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U. | | 登録日 | 2010-05-07 | | 公開日 | 2010-05-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
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2XST
 | | Crystal Structure of the Human Lipocalin 15 | | 分子名称: | 1,2-ETHANEDIOL, LIPOCALIN 15 | | 著者 | Muniz, J.R.C, Gileadi, C, Yue, W.W, Krojer, T, Ugochukwu, E, Phillips, C, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Kavanagh, K.L, Oppermann, U. | | 登録日 | 2010-09-30 | | 公開日 | 2010-10-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Crystal Structure of the Human Lipocalin 15
To be Published
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2XSN
 | | Crystal Structure of Human Tyrosine Hydroxylase Catalytic Domain | | 分子名称: | TYROSINE 3-MONOOXYGENASE, ZINC ION | | 著者 | Muniz, J.R.C, Cooper, C.D.O, Yue, W.W, Krysztofinska, E, von Delft, F, Knapp, S, Gileadi, O, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Kavanagh, K.L, Oppermann, U. | | 登録日 | 2010-10-29 | | 公開日 | 2010-11-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Crystal Structure of Human Tyrosine Hydroxylase Catalytic Domain
To be Published
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2Y1H
 | | Crystal structure of the human TatD-domain protein 3 (TATDN3) | | 分子名称: | 1,2-ETHANEDIOL, NICKEL (II) ION, PHOSPHATE ION, ... | | 著者 | Muniz, J.R.C, Puranik, S, Krojer, T, Yue, W.W, Ugochukwu, E, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Kavanagh, K.L, Oppermann, U. | | 登録日 | 2010-12-08 | | 公開日 | 2010-12-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of the Human Tatd-Domain Protein 3 (Tatdn3)
To be Published
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2XIO
 | | Structure of putative deoxyribonuclease TATDN1 isoform a | | 分子名称: | 1,2-ETHANEDIOL, NICKEL (II) ION, PUTATIVE DEOXYRIBONUCLEASE TATDN1, ... | | 著者 | Muniz, J.R.C, Cocking, R, Puranik, S, Krojer, T, Raynor, J, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W, Kavanagh, K.L, Oppermann, U. | | 登録日 | 2010-06-30 | | 公開日 | 2010-07-14 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | Structure of Putative Deoxyribonuclease Tatdn1 Isoform A
To be Published
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2WZ9
 | | Crystal structure of the thioredoxin domain of human TXNL2 | | 分子名称: | GLUTAREDOXIN-3 | | 著者 | Vollmar, M, Johannson, C, Cocking, R, Pike, A.C.W, Muniz, J.R.C, Edwards, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Kavanagh, K.L. | | 登録日 | 2009-11-25 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal Structure of the Thioredoxin Domain of Human Txnl2
To be Published
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2WWU
 | | Crystal structure of the catalytic domain of PHD finger protein 8 | | 分子名称: | ACETATE ION, NICKEL (II) ION, PHD FINGER PROTEIN 8, ... | | 著者 | Yue, W.W, Hozjan, V, Cooper, C, Tumber, A, Krojer, T, Muniz, J, Allerston, C, Salah, E, McDonough, M.A, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Schofield, C.J, Kavanagh, K.L, Oppermann, U. | | 登録日 | 2009-10-29 | | 公開日 | 2009-11-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase.
FEBS Lett., 584, 2010
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3NR3
 | | Crystal Structure of Human Peripheral Myelin Protein 2 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, CITRIC ACID, ... | | 著者 | Ugochukwu, E, Pilka, E, Phillips, C, Yue, W.W, Krojer, T, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Kavanagh, K.L, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2010-06-30 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure of Human Peripheral Myelin Protein 2
To be Published
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3ZYW
 | | Crystal structure of the first glutaredoxin domain of human glutaredoxin 3 (GLRX3) | | 分子名称: | 1,2-ETHANEDIOL, GLUTAREDOXIN-3 | | 著者 | Vollmar, M, Johansson, C, Cocking, R, Krojer, T, Muniz, J.R.C, Kavanagh, K.L, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Oppermann, U. | | 登録日 | 2011-08-29 | | 公開日 | 2012-02-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Crystal Structure of the First Glutaredoxin Domain of Human Glutaredoxin 3 (Glrx3)
To be Published
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4B4O
 | | Crystal Structure of human epimerase family protein SDR39U1 (isoform2) with NADPH | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, EPIMERASE FAMILY PROTEIN SDR39U1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Vollmar, M, Muniz, J.R.C, Shafqat, N, Picaud, S, Krojer, T, Chaikuad, A, Pike, A.C.W, Yue, W.W, Filippakopoulos, P, Kavanagh, K.L, von Delft, F, Weigelt, J, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U. | | 登録日 | 2012-07-31 | | 公開日 | 2012-08-29 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of Human Epimerase Family Protein Sdr39U1 (Isoform2) with Nadph
To be Published
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2FLS
 | | Crystal structure of Human Glutaredoxin 2 complexed with glutathione | | 分子名称: | GLUTATHIONE, Glutaredoxin-2 | | 著者 | Johansson, C, Smee, C, Kavanagh, K.L, Debreczeni, J, von Delft, F, Gileadi, O, Arrowsmith, C, Weigelt, J, Edwards, A, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2006-01-06 | | 公開日 | 2006-01-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of Human Glutaredoxin 2 complexed with glutathione
To be Published
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2GS3
 | | Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4) | | 分子名称: | CHLORIDE ION, Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Johansson, C, Kavanagh, K.L, Rojkova, A, Gileadi, O, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2006-04-25 | | 公開日 | 2006-05-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4)
To be Published
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2HE3
 | | Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2) | | 分子名称: | CHLORIDE ION, Glutathione peroxidase 2 | | 著者 | Johansson, C, Kavanagh, K.L, Rojkova, A, Gileadi, O, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2006-06-21 | | 公開日 | 2006-07-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
To be Published
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2HT9
 | | The structure of dimeric human glutaredoxin 2 | | 分子名称: | 12-mer peptide, FE2/S2 (INORGANIC) CLUSTER, GLUTATHIONE, ... | | 著者 | Johansson, C, Smee, C, Kavanagh, K.L, Debreczeni, J, von Delft, F, Gileadi, O, Arrowsmith, C, Weigelt, J, Edwards, A, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2006-07-25 | | 公開日 | 2006-08-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria
J.Biol.Chem., 282, 2007
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2OPW
 | | Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo) | | 分子名称: | PHYHD1 protein | | 著者 | Zhang, Z, Butler, D, McDonough, M.A, Kavanagh, K.L, Bray, J.E, Ng, S.S, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-01-30 | | 公開日 | 2007-03-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of human phytanoyl-CoA dioxygenase PHYHD1 (apo)
To be Published
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2OQ6
 | | Crystal structure of JMJD2A complexed with histone H3 peptide trimethylated at Lys9 | | 分子名称: | JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, NICKEL (II) ION, ... | | 著者 | Pilka, E.S, Ng, S.S, Kavanagh, K.L, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-01-31 | | 公開日 | 2007-03-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
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2P02
 | | Crystal structure of the alpha subunit of human S-adenosylmethionine synthetase 2 | | 分子名称: | CHLORIDE ION, S-ADENOSYLMETHIONINE, S-adenosylmethionine synthetase isoform type-2 | | 著者 | Papagrigoriou, E, Shafqat, N, Rojkova, A, Niessen, F.H, Kavanagh, K.L, von Delft, F, Gorrec, F, Ugochukwu, E, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-02-28 | | 公開日 | 2007-03-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | | 主引用文献 | Crystal structure of the alpha subunit of human S-adenosylmethionine synthetase 2
To be Published
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2Q9V
 | | Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase | | 分子名称: | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | | 著者 | Pilka, E.S, Hozjan, V, Kavanagh, K.L, Papagrigoriou, E, Cooper, C, Elkins, J.M, Doyle, D.A, von Delft, F, Sundstrom, M, Arrowsmith, C.A, Weigelt, J, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-06-14 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the C890S mutant of the 4th PDZ domain of human membrane associated guanylate kinase.
To be Published
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2OX0
 | | Crystal structure of JMJD2A complexed with histone H3 peptide dimethylated at Lys9 | | 分子名称: | CHLORIDE ION, JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, ... | | 著者 | Pilka, E.S, Ng, S.S, Kavanagh, K.L, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-02-19 | | 公開日 | 2007-03-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
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2PN8
 | | Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase) | | 分子名称: | Peroxiredoxin-4 | | 著者 | Pilka, E.S, Kavanagh, K.L, Cooper, C, von Delft, F, Sundstrom, M, Arrowsmith, C.A, Weigelt, J, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-04-24 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of human peroxiredoxin 4 (thioredoxin peroxidase).
To be Published
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