2WUL

CRYSTAL STRUCTURE OF THE HUMAN GLUTAREDOXIN 5 WITH BOUND GLUTATHIONE IN AN FES CLUSTER

Replaces:  2WEM

Summary for 2WUL

• Entry DOI: 10.2210/pdb2wul/pdb
• Descriptor: GLUTAREDOXIN RELATED PROTEIN 5, GLUTATHIONE, FE2/S2 (INORGANIC) CLUSTER, ... (6 entities in total)
• Functional Keywords: chromosome 14 open reading frame 87, oxidoreductase, thioredoxin family, glrx5, pr01238, flb4739
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Mitochondrion matrix : Q86SX6
• Total number of polymer chains: 4
• Total formula weight: 53291.12

Authors

Roos, A.K.,Johansson, C.,Guo, K.,Yue, W.W.,Pike, A.C.W.,Cooper, C.D.O.,Pilka, E.S.,Kavanagh, K.L.,Chaikuad, A.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (deposition date: 2009-10-06, release date: 2009-10-20, Last modification date: 2023-12-20)

• Primary citation: Johansson, C.,Roos, A.K.,Montano, S.J.,Sengupta, R.,Filippakopoulos, P.,Guo, K.,von Delft, F.,Holmgren, A.,Oppermann, U.,Kavanagh, K.L.; The Crystal Structure of Human Glrx5: Iron Sulphur Cluster Coordination, Tetrameric Assembly and Monomer Activity.; Biochem.J., 433:303-, 2011; PubMed: 21029046; DOI: 10.1042/BJ20101286

Experimental method

X-RAY DIFFRACTION (2.4 Å)