2WUL

CRYSTAL STRUCTURE OF THE HUMAN GLUTAREDOXIN 5 WITH BOUND GLUTATHIONE IN AN FES CLUSTER

Replaces:  2WEM

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	GLUTAREDOXIN RELATED PROTEIN 5	polymer	118	12865.6	4	UniProt (Q86SX6) Pfam (PF00462)	HOMO SAPIENS (HUMAN)
2	E, G, J, L (A, B, C, D)	GLUTATHIONE	non-polymer		307.3	4	Chemie (GSH) PubChem (124886) PubChem (54289881) PubChem (59012062) PubChem (445616) PubChem (448041) PubChem (745) PubChem (9839547) PubChem (10924820) PubChem (15559593)
3	F, K (A, C)	FE2/S2 (INORGANIC) CLUSTER	non-polymer		175.8	2	Chemie (FES)
4	H, M, N, O (B, D)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL) PubChem (312)
5	I (B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG) PubChem (8117)
6	P, Q, R, S (A, B, C, D)	water	water		18.0	93	Chemie (HOH)

Sequence modifications

A, B, C, D: 33 - 34 (PDB: 2WUL)
A, B, C, D: 35 - 150 (UniProt: Q86SX6)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	51462.3
Non-Polymers*	Number of molecules	11
	Total formula weight	1828.9
All*	Total formula weight	53291.1

*Water molecules are not included.