1SM9

Crystal Structure Of An Engineered K274RN276D Double Mutant of Xylose Reductase From Candida Tenuis Optimized To Utilize NAD

Summary for 1SM9

Entry DOI	10.2210/pdb1sm9/pdb
Descriptor	xylose reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
Functional Keywords	xylose metabolism, coenzyme specificity, aldo-keto reductase, beta-alpha-barrel, akr2b5, oxidoreductase
Biological source	Candida tenuis
Total number of polymer chains	4
Total formula weight	147018.50
Authors	Petschacher, B.,Leitgeb, S.,Kavanagh, K.L.,Wilson, D.K.,Nidetzky, B. (deposition date: 2004-03-08, release date: 2004-12-21, Last modification date: 2023-08-23)
Primary citation	Petschacher, B.,Leitgeb, S.,Kavanagh, K.L.,Wilson, D.K.,Nidetzky, B. The coenzyme specificity of Candida tenuis xylose reductase (AKR2B5) explored by site-directed mutagenesis and X-ray crystallography. Biochem.J., 385:75-83, 2005 Cited by PubMed: 15320875 DOI: 10.1042/BJ20040363 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation