8BHH
 
 | | The crystal structure of a feruloyl esterase C from Fusarium oxysporum in complex with p-coumaric acid | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4'-HYDROXYCINNAMIC ACID, ... | | Authors: | Dimarogona, M, Topakas, E, Kosinas, C, Ferousi, C, Nikolaivits, E. | | Deposit date: | 2022-10-31 | | Release date: | 2023-07-05 | | Last modified: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Crystal structure of the Fusarium oxysporum tannase-like feruloyl esterase FaeC in complex with p-coumaric acid provides insight into ligand binding.
Febs Lett., 597, 2023
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8P1G
 | | Crystal structure of inactive TtCE16 in complex with acetate | | Descriptor: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Dimarogona, M, Kosinas, C, Pentari, C, Zerva, A, Topakas, E, Karampa, P. | | Deposit date: | 2023-05-12 | | Release date: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | The role of CE16 exo-deacetylases in hemicellulolytic enzyme mixtures revealed by the biochemical and structural study of the novel TtCE16B esterase.
Carbohydr Polym, 327, 2024
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5AJH
 | | Crystal structure of Fusarium oxysporum cutinase | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CUTINASE | | Authors: | Dimarogona, M, Nikolaivits, E, Kanelli, M, Christakopoulos, P, Sandgren, M, Topakas, E. | | Deposit date: | 2015-02-24 | | Release date: | 2015-09-02 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and Functional Studies of a Fusarium Oxysporum Cutinase with Polyethylene Terephthalate Modification Potential.
Biochim.Biophys.Acta, 1850, 2015
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7SC0
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3FPX
 | | Native fungus laccase from Trametes hirsuta | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... | | Authors: | Polyakov, K.M, Fedorova, T.V, Stepanova, E.V, Cherkashin, E.A, Kurzeev, S.A, Strokopytov, B.V, Lamzin, V.S, Koroleva, O.V. | | Deposit date: | 2009-01-06 | | Release date: | 2009-01-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of native laccase from Coriolus hirsutus at 1.8 A resolution
To be Published
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2VA0
 | | Differential regulation of the xylan degrading apparatus of Cellvibrio japonicus by a novel two component system | | Descriptor: | ABFS ARABINOFURANOSIDASE TWO COMPONENT SYSTEM SENSOR PROTEIN, CHLORIDE ION, PHOSPHATE ION | | Authors: | Murray, J.W, Emami, K, Topakas, E, Nagy, T, Henshaw, J, Jackson, K.A, Nelson, K.E, Mongodin, E.F, Lewis, R.J, Gilbert, H.J. | | Deposit date: | 2007-08-28 | | Release date: | 2008-10-14 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.602 Å) | | Cite: | Regulation of the Xylan-Degrading Apparatus of Cellvibrio Japonicus by a Novel Two-Component System.
J.Biol.Chem., 284, 2009
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2W9X
 | | The active site of a carbohydrate esterase displays divergent catalytic and non-catalytic binding functions | | Descriptor: | GLYCEROL, PUTATIVE ACETYL XYLAN ESTERASE | | Authors: | Montanier, C, Money, V.A, Pires, V, Flint, J.E, Benedita, P.A, Goyal, A, Prates, J.A, Izumi, A, Stalbrand, H, Morland, C, Cartmell, A, Kolenova, K, Topakas, E, Dobson, E, Bolam, D.N, Davies, G.J, Fontes, C.M, Gilbert, H.J. | | Deposit date: | 2009-01-29 | | Release date: | 2009-03-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions.
Plos Biol., 7, 2009
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2WAO
 | | Structure of a family two carbohydrate esterase from Clostridium thermocellum in complex with cellohexaose | | Descriptor: | ENDOGLUCANASE E, FORMIC ACID, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Montainer, C, Money, V.A, Pires, V.M.R, Flint, J.E, Pinheiro, B.A, Goyal, A, Prates, J.A.M, Izumi, A, Stalbrand, H, Kolenova, K, Topakas, E, Dodson, E.J, Bolam, D.N, Davies, G.J, Fontes, C.M.G.A, Gilbert, H.J. | | Deposit date: | 2009-02-10 | | Release date: | 2009-10-06 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions.
Plos Biol., 7, 2009
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7UUY
 | | Structure of the sodium/iodide symporter (NIS) | | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, Sodium/iodide cotransporter | | Authors: | Ravera, S, Nicola, J.P, Salazar-De Simone, G, Sigworth, F, Karakas, E, Amzel, L.M, Bianchet, M, Carrasco, N. | | Deposit date: | 2022-04-29 | | Release date: | 2022-12-21 | | Last modified: | 2023-01-04 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural insights into the mechanism of the sodium/iodide symporter.
Nature, 612, 2022
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7UUZ
 | | Structure of the sodium/iodide symporter (NIS) in complex with perrhenate and sodium | | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, PERRHENATE, SODIUM ION, ... | | Authors: | Ravera, S, Nicola, J.P, Salazar-De Simone, G, Sigworth, F, Karakas, E, Amzel, L.M, Bianchet, M, Carrasco, N. | | Deposit date: | 2022-04-29 | | Release date: | 2022-12-21 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into the mechanism of the sodium/iodide symporter.
Nature, 612, 2022
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5TQ0
 | | Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in the presence of EDTA | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB, HEAVY CHAIN, ... | | Authors: | Romero-Hernandez, A, Simorowski, N, Karakas, E, Furukawa, H. | | Deposit date: | 2016-10-21 | | Release date: | 2016-12-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
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5B3J
 | | Activation of NMDA receptors and the mechanism of inhibition by ifenprodil | | Descriptor: | Fab, heavy chain, light chain, ... | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-01 | | Release date: | 2016-05-11 | | Last modified: | 2022-03-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
Nature, 534, 2016
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5TPZ
 | | Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2B in apo closed state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 2B, ... | | Authors: | Romero-Hernandez, A, Simorwski, N, Karakas, E, Furukawa, H. | | Deposit date: | 2016-10-21 | | Release date: | 2016-12-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.095 Å) | | Cite: | Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
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5TQ2
 | | Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at GluN1 and GluN2A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB, HEAVY CHAIN, ... | | Authors: | Romero-Hernandez, A, Simorowski, N, Karakas, E, Furukawa, H. | | Deposit date: | 2016-10-21 | | Release date: | 2016-12-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.289 Å) | | Cite: | Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
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5TPW
 | | Crystal structure of amino terminal domains of the NMDA receptor subunit GluN1 and GluN2A in complex with zinc at the GluN2A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB, HEAVY CHAIN, ... | | Authors: | Romero-Hernandez, A, Simorowski, N, Karakas, E, Furukawa, H. | | Deposit date: | 2016-10-21 | | Release date: | 2016-12-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.909 Å) | | Cite: | Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.
Neuron, 92, 2016
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7ZN6
 | | Crystal structure of laccase-like multicopper oxidase (LMCO) from Thermothelomyces thermophilus | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Kosinas, C, Dimarogona, M, Zerva, A, Topakas, E. | | Deposit date: | 2022-04-20 | | Release date: | 2023-06-28 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure-function studies of a novel laccase-like multicopper oxidase from Thermothelomyces thermophila provide insights into its biological role.
Acta Crystallogr D Struct Biol, 79, 2023
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7ZTN
 | | Crystal structure of fungal CE16 acetyl xylan esterase | | Descriptor: | 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Dimarogona, M, Kosinas, C, Pentari, C, Zerva, A, Topakas, E. | | Deposit date: | 2022-05-10 | | Release date: | 2023-08-23 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The role of CE16 exo-deacetylases in hemicellulolytic enzyme mixtures revealed by the biochemical and structural study of the novel TtCE16B esterase.
Carbohydr Polym, 327, 2024
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4G4I
 | | Crystal structure of glucuronoyl esterase S213A mutant from Sporotrichum thermophile determined at 1.9 A resolution | | Descriptor: | 1,2-ETHANEDIOL, 4-O-methyl-glucuronoyl methylesterase, GLYCEROL | | Authors: | Charvagi, M.D, Dimarogona, M, Topakas, E, Christakopoulos, P, Chrysina, E.D. | | Deposit date: | 2012-07-16 | | Release date: | 2013-01-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The structure of a novel glucuronoyl esterase from Myceliophthora thermophila gives new insights into its role as a potential biocatalyst.
Acta Crystallogr.,Sect.D, 69, 2013
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4G4J
 | | Crystal structure of glucuronoyl esterase S213A mutant from Sporotrichum thermophile in complex with methyl 4-O-methyl-beta-D-glucopyranuronate determined at 2.35 A resolution | | Descriptor: | 1,2-ETHANEDIOL, 4-O-methyl-glucuronoyl methylesterase, GLYCEROL, ... | | Authors: | Charavgi, M.D, Dimarogona, M, Topakas, E, Christakopoulos, P, Chrysina, E.D. | | Deposit date: | 2012-07-16 | | Release date: | 2013-01-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | The structure of a novel glucuronoyl esterase from Myceliophthora thermophila gives new insights into its role as a potential biocatalyst.
Acta Crystallogr.,Sect.D, 69, 2013
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4G4G
 | | Crystal structure of recombinant glucuronoyl esterase from Sporotrichum thermophile determined at 1.55 A resolution | | Descriptor: | 1,2-ETHANEDIOL, 4-O-methyl-glucuronoyl methylesterase, GLYCEROL | | Authors: | Charavgi, M.D, Dimarogona, M, Topakas, E, Christakopoulos, P, Chrysina, E.D. | | Deposit date: | 2012-07-16 | | Release date: | 2013-01-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | The structure of a novel glucuronoyl esterase from Myceliophthora thermophila gives new insights into its role as a potential biocatalyst.
Acta Crystallogr.,Sect.D, 69, 2013
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3U7B
 | | A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft | | Descriptor: | 1,2-ETHANEDIOL, ENDO-1,4-BETA-XYLANASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Dimarogona, M, Topakas, E, Christakopoulos, P, Chrysina, E.D. | | Deposit date: | 2011-10-13 | | Release date: | 2012-07-18 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | The structure of a GH10 xylanase from Fusarium oxysporum reveals the presence of an extended loop on top of the catalytic cleft.
Acta Crystallogr.,Sect.D, 68, 2012
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5FXK
 | | GluN1b-GluN2B NMDA receptor structure-Class Y | | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-02 | | Release date: | 2016-05-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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5FXH
 | | GluN1b-GluN2B NMDA receptor in non-active-1 conformation | | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-02 | | Release date: | 2016-05-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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5FXG
 | | GLUN1B-GLUN2B NMDA RECEPTOR IN ACTIVE CONFORMATION | | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-02 | | Release date: | 2016-05-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.8 Å) | | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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5FXI
 | | GluN1b-GluN2B NMDA receptor structure in non-active-2 conformation | | Descriptor: | N-METHYL-D-ASPARTATE RECEPTOR GLUN1, N-METHYL-D-ASPARTATE RECEPTOR GLUN2B | | Authors: | Tajima, N, Karakas, E, Grant, T, Simorowski, N, Diaz-Avalos, R, Grigorieff, N, Furukawa, H. | | Deposit date: | 2016-03-02 | | Release date: | 2016-05-11 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (6.4 Å) | | Cite: | Activation of Nmda Receptors and the Mechanism of Inhibition by Ifenprodil.
Nature, 534, 2016
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