3H8K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3h8k by Molmil](/molmil-images/mine/3h8k) | Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution | Descriptor: | Autocrine motility factor receptor, isoform 2, Ubiquitin-conjugating enzyme E2 G2 | Authors: | Kalathur, R.C, Das, R, Li, J, Byrd, R.A, Ji, X. | Deposit date: | 2009-04-29 | Release date: | 2009-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Allosteric activation of E2-RING finger-mediated ubiquitylation by a structurally defined specific E2-binding region of gp78. Mol.Cell, 34, 2009
|
|
6ARX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6arx by Molmil](/molmil-images/mine/6arx) | Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in the ligand-free state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, CHLORIDE ION, ... | Authors: | Cheung, J, Mahmood, A, Kalathur, R, Lixuan, L, Carlier, P.R. | Deposit date: | 2017-08-23 | Release date: | 2018-01-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.302 Å) | Cite: | Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance. Structure, 26, 2018
|
|
6ARY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ary by Molmil](/molmil-images/mine/6ary) | Crystal structure of an insecticide-resistant acetylcholinesterase mutant from the malaria vector Anopheles gambiae in complex with a difluoromethyl ketone inhibitor | Descriptor: | (1S)-2,2-difluoro-1-[1-(pentan-3-yl)-1H-pyrazol-4-yl]ethan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... | Authors: | Cheung, J, Mahmood, A, Kalathur, R, Lixuan, L, Carlier, P.R. | Deposit date: | 2017-08-23 | Release date: | 2018-01-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.257 Å) | Cite: | Structure of the G119S Mutant Acetylcholinesterase of the Malaria Vector Anopheles gambiae Reveals Basis of Insecticide Resistance. Structure, 26, 2018
|
|
7K0N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0n by Molmil](/molmil-images/mine/7k0n) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 2 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | Deposit date: | 2020-09-04 | Release date: | 2021-02-24 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|
7K0O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0o by Molmil](/molmil-images/mine/7k0o) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 3 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | Deposit date: | 2020-09-04 | Release date: | 2021-02-24 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|
7K0P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0p by Molmil](/molmil-images/mine/7k0p) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 4 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | Deposit date: | 2020-09-04 | Release date: | 2021-02-24 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|
7K0M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0m by Molmil](/molmil-images/mine/7k0m) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 1 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | Deposit date: | 2020-09-04 | Release date: | 2021-02-24 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|
7K0K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0k by Molmil](/molmil-images/mine/7k0k) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, 3KS-bound | Descriptor: | 3-Dehydrosphinganine, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | Deposit date: | 2020-09-04 | Release date: | 2021-02-24 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|
7K0J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0j by Molmil](/molmil-images/mine/7k0j) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa protomer | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | Deposit date: | 2020-09-04 | Release date: | 2021-02-24 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|
7K0Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0q by Molmil](/molmil-images/mine/7k0q) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound | Descriptor: | Myriocin, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | Deposit date: | 2020-09-04 | Release date: | 2021-02-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|
7K0L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0l by Molmil](/molmil-images/mine/7k0l) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, myriocin-bound | Descriptor: | Myriocin, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | Deposit date: | 2020-09-04 | Release date: | 2021-02-24 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|
7K0I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k0i by Molmil](/molmil-images/mine/7k0i) | Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ... | Authors: | Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H. | Deposit date: | 2020-09-04 | Release date: | 2021-02-24 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat.Struct.Mol.Biol., 28, 2021
|
|