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PDB: 14 results

3OFI
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BU of 3ofi by Molmil
Crystal structure of human insulin-degrading enzyme in complex with ubiquitin
Descriptor: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, Ubiquitin, ...
Authors:Kalas, V, Ralat, L.A, Tang, W.-J.
Deposit date:2010-08-15
Release date:2010-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Ubiquitin is a novel substrate for human insulin-degrading enzyme.
J.Mol.Biol., 406, 2011
5F2F
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BU of 5f2f by Molmil
Crystal structure of para-biphenyl-2-methyl-3', 5' di-methyl amide mannoside bound to FimH lectin domain
Descriptor: 5-[4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3-methyl-phenyl]-~{N}1,~{N}3-dimethyl-benzene-1,3-dicarboxamide, GLYCEROL, Protein FimH
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2015-12-01
Release date:2016-05-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.665 Å)
Cite:Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI.
Chemmedchem, 11, 2016
5JR4
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BU of 5jr4 by Molmil
Crystal structure of FimH A27V/V163A from E. coli UTI89 bound to FimG N-terminal extension
Descriptor: CALCIUM ION, FimG N-terminal extension, GLYCEROL, ...
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2016-05-05
Release date:2017-02-22
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.596 Å)
Cite:Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.
Sci Adv, 3, 2017
5JQI
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BU of 5jqi by Molmil
Crystal structure of FimH A62S from E. coli UTI89 bound to FimG N-terminal extension
Descriptor: FimG N-terminal extension, GLYCEROL, Type 1 fimbiral adhesin FimH
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2016-05-05
Release date:2017-02-22
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.962 Å)
Cite:Evolutionary fine-tuning of conformational ensembles in FimH during host-pathogen interactions.
Sci Adv, 3, 2017
6AOX
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BU of 6aox by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with TF antigen
Descriptor: Fml fimbrial adhesin FmlD, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-16
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
6AS8
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BU of 6as8 by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with ortho-biphenyl-2'-carboxyl N-acetyl-beta-galactosaminoside
Descriptor: Fml fimbrial adhesin FmlD, ortho-biphenyl-2'-carboxyl N-acetyl-beta-galactosaminoside
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-23
Release date:2018-02-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
6ARO
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BU of 6aro by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with 8-hydroxyquinoline beta-galactoside
Descriptor: 8-hydroxyquinoline beta-galactopyranoside, F9 pilus adhesin FmlH, SULFATE ION
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-23
Release date:2018-02-28
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
6AOW
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BU of 6aow by Molmil
Crystal structure of lectin domain of F9 pilus adhesin FmlH from E. coli UTI89
Descriptor: F9 pilus adhesin FmlH, SULFATE ION
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-16
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
6ARM
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BU of 6arm by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-nitrophenyl beta-galactoside (ONPG)
Descriptor: 2-nitrophenyl beta-D-galactopyranoside, F9 pilus adhesin FmlH, SULFATE ION
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-22
Release date:2018-02-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
6ARN
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BU of 6arn by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-methoxyphenyl beta-galactoside (OMPG)
Descriptor: 2-methoxyphenyl beta-D-galactopyranoside, Putative Fml fimbrial adhesin FmlD, SULFATE ION
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-22
Release date:2018-02-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
6AOY
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BU of 6aoy by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-nitrophenyl beta-galactoside (ONPG)
Descriptor: 2-nitrophenyl beta-D-galactopyranoside, Fml fimbrial adhesin FmlD, SULFATE ION
Authors:Kalas, V, Hultgren, S.J.
Deposit date:2017-08-16
Release date:2018-02-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
8DEZ
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BU of 8dez by Molmil
Abp2D Receptor Binding Domain ACICU
Descriptor: Abp2D Receptor Binding Domain, CITRATE ANION, SULFATE ION
Authors:Tamadonfar, K.O, Pinkner, J.P, Dodson, K.W, Kalas, V, Hultgren, S.J.
Deposit date:2022-06-21
Release date:2023-03-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.29 Å)
Cite:Structure-function correlates of fibrinogen binding by Acinetobacter adhesins critical in catheter-associated urinary tract infections.
Proc.Natl.Acad.Sci.USA, 120, 2023
5LNG
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BU of 5lng by Molmil
Lectin domain of E. coli F9 pilus adhesin FmlH
Descriptor: Putative Fml fimbrial adhesin FmlD, SULFATE ION
Authors:Ruer, S, Conover, M.S, Kalas, V, Taganna, J, De Greve, H, Pinkner, J.S, Dodson, K.W, Hultgren, S.J, Remaut, H.
Deposit date:2016-08-04
Release date:2016-10-05
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection.
Cell Host Microbe, 20, 2016
5LNE
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BU of 5lne by Molmil
E. coli F9 pilus adhesin FmlH bound to the Thomsen-Friedenreich (TF) antigen
Descriptor: NICKEL (II) ION, Putative Fml fimbrial adhesin FmlD, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose
Authors:Ruer, S, Conover, M.S, Kalas, V, Taganna, J, De Greve, H, Pinkner, J.S, Dodson, K.W, Hultgren, S.J, Remaut, H.
Deposit date:2016-08-04
Release date:2016-10-05
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection.
Cell Host Microbe, 20, 2016

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