5LNE

E. coli F9 pilus adhesin FmlH bound to the Thomsen-Friedenreich (TF) antigen

Summary for 5LNE

DescriptorPutative Fml fimbrial adhesin FmlD, N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE, BETA-D-GALACTOSE, ... (5 entities in total)
Functional Keywordsfimbrial adhesin, lectin, o-glycan, cell adhesion
Biological sourceEscherichia coli
Total number of polymer chains2
Total molecular weight36473.39
Authors
Ruer, S.,Conover, M.S.,Kalas, V.,Taganna, J.,De Greve, H.,Pinkner, J.S.,Dodson, K.W.,Hultgren, S.J.,Remaut, H. (deposition date: 2016-08-04, release date: 2016-10-05, Last modification date: 2018-01-31)
Primary citation
Conover, M.S.,Ruer, S.,Taganna, J.,Kalas, V.,De Greve, H.,Pinkner, J.S.,Dodson, K.W.,Remaut, H.,Hultgren, S.J.
Inflammation-Induced Adhesin-Receptor Interaction Provides a Fitness Advantage to Uropathogenic E. coli during Chronic Infection.
Cell Host Microbe, 20:482-492, 2016
PubMed: 27667696 (PDB entries with the same primary citation)
DOI: 10.1016/j.chom.2016.08.013
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.225100.4%1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5lne
no rotation
Molmil generated image of 5lne
rotated about x axis by 90°
Molmil generated image of 5lne
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 5lne
no rotation
Molmil generated image of 5lne
rotated about x axis by 90°
Molmil generated image of 5lne
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (5lne.pdb1.gz [50.7 KB])
Coordinate files for Biological unit (5lne.pdb2.gz [53.07 KB])