7NOE
| Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 3'5 | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NO2
| Structure of the mature RSV CA lattice: hexamer derived from tubes (C2-symmetric) | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOF
| Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 4'4 | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NO6
| Structure of the mature RSV CA lattice: Group I, pentamer-hexamer interface, class 1 | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOD
| Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 3'4 | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NON
| Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 4'Gamma | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NO9
| Structure of the mature RSV CA lattice: Group I, pentamer-pentamer interface, class 1'1 | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOO
| Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 5'Alpha | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (7.9 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NO5
| Structure of the mature RSV CA lattice: hexamer with 2 adjacent pentamers (C2 symmetric) | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOK
| Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 3'Gamma | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NO7
| Structure of the mature RSV CA lattice: Group I, pentamer-hexamer interface, class 1"2 | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOL
| Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 4'Alpha | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NO4
| Structure of the mature RSV CA lattice: hexamer with 3 adjacent pentamers (C3 symmetric) | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOJ
| Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 3'Beta | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOC
| Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 3'3 | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOP
| Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 5'Beta | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOA
| Structure of the mature RSV CA lattice: Group II, hexamer-hexamer interface, class 6 | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (6.4 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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7NOQ
| Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 5'Gamma | Descriptor: | Capsid protein p27, alternate cleaved 1 | Authors: | Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A. | Deposit date: | 2021-02-25 | Release date: | 2021-04-21 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer. Nat Commun, 12, 2021
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4APP
| Crystal Structure of the Human p21-Activated Kinase 4 in Complex with (S)-N-(5-(3-benzyl-1-methylpiperazine-4-carbonyl)-6,6-dimethyl-1,4,5, 6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-3-phenoxybenzamide | Descriptor: | GLYCEROL, N-[6,6-dimethyl-5-[(2S)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamide, SERINE/THREONINE-PROTEIN KINASE PAK 4 | Authors: | Knighton, D.D, Deng, Y.L, Wang, C, Guo, C, McAlpine, I, Zhang, J, Kephart, S, Johnson, M.C, Li, H, Bouzida, D, Yang, A, Dong, L, Marakovits, J, Tikhe, J, Richardson, P, Guo, L.C, Kania, R, Edwards, M.P, Kraynov, E, Christensen, J, Piraino, J, Lee, J, Dagostino, E, Del-Carmen, C, Smeal, T, Murray, B.W. | Deposit date: | 2012-04-04 | Release date: | 2012-06-06 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of Pyrroloaminopyrazoles as Novel Pak Inhibitors. J.Med.Chem., 55, 2012
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7SD0
| Cryo-EM structure of the SHOC2:PP1C:MRAS complex | Descriptor: | Leucine-rich repeat protein SHOC-2, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Liau, N.P.D, Johnson, M.C, Hymowitz, S.G, Sudhamsu, J. | Deposit date: | 2021-09-29 | Release date: | 2022-04-20 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural basis for SHOC2 modulation of RAS signalling. Nature, 609, 2022
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7T4Q
| CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with neutralizing fabs 2C12, 7I13 and 13H11 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... | Authors: | Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. | Deposit date: | 2021-12-10 | Release date: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
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7T4R
| CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and neutralizing fabs MSL-109 and 13H11 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... | Authors: | Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. | Deposit date: | 2021-12-10 | Release date: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
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7T4S
| CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with NRP2 and neutralizing fabs 8I21 and 13H11 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein H, ... | Authors: | Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C. | Deposit date: | 2021-12-10 | Release date: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for HCMV Pentamer receptor recognition and antibody neutralization. Sci Adv, 8, 2022
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6OIG
| Subunit joining exposes nascent pre-40S rRNA for processing and quality control | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Rai, J, Parker, M.D, Ghalei, H, Johnson, M.C, Karbstein, K, Stroupe, M.E. | Deposit date: | 2019-04-09 | Release date: | 2020-09-30 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7. Rna, 27, 2021
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8ETR
| CryoEM Structure of NLRP3 NACHT domain in complex with G2394 | Descriptor: | (6S,8R)-N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Murray, J.M, Johnson, M.C. | Deposit date: | 2022-10-17 | Release date: | 2022-11-02 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Overcoming Preclinical Safety Obstacles to Discover ( S )- N -((1,2,3,5,6,7-Hexahydro- s -indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5 H -pyrazolo[5,1- b ][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor. J.Med.Chem., 65, 2022
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