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PDB: 54 results

7NOE
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BU of 7noe by Molmil
Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 3'5
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NO2
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BU of 7no2 by Molmil
Structure of the mature RSV CA lattice: hexamer derived from tubes (C2-symmetric)
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NOF
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BU of 7nof by Molmil
Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 4'4
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NO6
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BU of 7no6 by Molmil
Structure of the mature RSV CA lattice: Group I, pentamer-hexamer interface, class 1
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NOD
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BU of 7nod by Molmil
Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 3'4
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NON
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BU of 7non by Molmil
Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 4'Gamma
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NO9
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BU of 7no9 by Molmil
Structure of the mature RSV CA lattice: Group I, pentamer-pentamer interface, class 1'1
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NOO
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BU of 7noo by Molmil
Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 5'Alpha
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NO5
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BU of 7no5 by Molmil
Structure of the mature RSV CA lattice: hexamer with 2 adjacent pentamers (C2 symmetric)
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (7.4 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NOK
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BU of 7nok by Molmil
Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 3'Gamma
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NO7
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BU of 7no7 by Molmil
Structure of the mature RSV CA lattice: Group I, pentamer-hexamer interface, class 1"2
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NOL
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BU of 7nol by Molmil
Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 4'Alpha
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NO4
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BU of 7no4 by Molmil
Structure of the mature RSV CA lattice: hexamer with 3 adjacent pentamers (C3 symmetric)
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NOJ
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BU of 7noj by Molmil
Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 3'Beta
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NOC
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BU of 7noc by Molmil
Structure of the mature RSV CA lattice: Group III, hexamer-hexamer interface, class 3'3
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NOP
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BU of 7nop by Molmil
Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 5'Beta
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NOA
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BU of 7noa by Molmil
Structure of the mature RSV CA lattice: Group II, hexamer-hexamer interface, class 6
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
7NOQ
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BU of 7noq by Molmil
Structure of the mature RSV CA lattice: Group IV, hexamer-hexamer interface, class 5'Gamma
Descriptor: Capsid protein p27, alternate cleaved 1
Authors:Obr, M, Ricana, C.L, Nikulin, N, Feathers, J.-P.R, Klanschnig, M, Thader, A, Johnson, M.C, Vogt, V.M, Schur, F.K.M, Dick, R.A.
Deposit date:2021-02-25
Release date:2021-04-21
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer.
Nat Commun, 12, 2021
4APP
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BU of 4app by Molmil
Crystal Structure of the Human p21-Activated Kinase 4 in Complex with (S)-N-(5-(3-benzyl-1-methylpiperazine-4-carbonyl)-6,6-dimethyl-1,4,5, 6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-3-phenoxybenzamide
Descriptor: GLYCEROL, N-[6,6-dimethyl-5-[(2S)-4-methyl-2-(phenylmethyl)piperazin-1-yl]carbonyl-2,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-phenoxy-benzamide, SERINE/THREONINE-PROTEIN KINASE PAK 4
Authors:Knighton, D.D, Deng, Y.L, Wang, C, Guo, C, McAlpine, I, Zhang, J, Kephart, S, Johnson, M.C, Li, H, Bouzida, D, Yang, A, Dong, L, Marakovits, J, Tikhe, J, Richardson, P, Guo, L.C, Kania, R, Edwards, M.P, Kraynov, E, Christensen, J, Piraino, J, Lee, J, Dagostino, E, Del-Carmen, C, Smeal, T, Murray, B.W.
Deposit date:2012-04-04
Release date:2012-06-06
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of Pyrroloaminopyrazoles as Novel Pak Inhibitors.
J.Med.Chem., 55, 2012
7SD0
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BU of 7sd0 by Molmil
Cryo-EM structure of the SHOC2:PP1C:MRAS complex
Descriptor: Leucine-rich repeat protein SHOC-2, MAGNESIUM ION, MANGANESE (II) ION, ...
Authors:Liau, N.P.D, Johnson, M.C, Hymowitz, S.G, Sudhamsu, J.
Deposit date:2021-09-29
Release date:2022-04-20
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis for SHOC2 modulation of RAS signalling.
Nature, 609, 2022
7T4Q
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BU of 7t4q by Molmil
CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with neutralizing fabs 2C12, 7I13 and 13H11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
Authors:Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C.
Deposit date:2021-12-10
Release date:2022-03-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Sci Adv, 8, 2022
7T4R
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BU of 7t4r by Molmil
CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and neutralizing fabs MSL-109 and 13H11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
Authors:Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C.
Deposit date:2021-12-10
Release date:2022-03-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Sci Adv, 8, 2022
7T4S
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BU of 7t4s by Molmil
CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with NRP2 and neutralizing fabs 8I21 and 13H11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein H, ...
Authors:Kschonsak, M, Johnson, M.C, Schelling, R, Green, E.M, Rouge, L, Ho, H, Patel, N, Kilic, C, Kraft, E, Arthur, C.P, Rohou, A.L, Comps-Agrar, L, Martinez-Martin, N, Perez, L, Payandeh, J, Ciferri, C.
Deposit date:2021-12-10
Release date:2022-03-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Sci Adv, 8, 2022
6OIG
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BU of 6oig by Molmil
Subunit joining exposes nascent pre-40S rRNA for processing and quality control
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Rai, J, Parker, M.D, Ghalei, H, Johnson, M.C, Karbstein, K, Stroupe, M.E.
Deposit date:2019-04-09
Release date:2020-09-30
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7.
Rna, 27, 2021
8ETR
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BU of 8etr by Molmil
CryoEM Structure of NLRP3 NACHT domain in complex with G2394
Descriptor: (6S,8R)-N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Murray, J.M, Johnson, M.C.
Deposit date:2022-10-17
Release date:2022-11-02
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Overcoming Preclinical Safety Obstacles to Discover ( S )- N -((1,2,3,5,6,7-Hexahydro- s -indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5 H -pyrazolo[5,1- b ][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor.
J.Med.Chem., 65, 2022

221716

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