6I23
 
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | 1,2-ETHANEDIOL, 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-5-O-phosphono-D-ribitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | 著者 | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | 登録日 | 2018-10-31 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
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6I22
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | Aureochrome1-like protein, FLAVIN MONONUCLEOTIDE | | 著者 | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | 登録日 | 2018-10-31 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
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6I21
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | 1,2-ETHANEDIOL, Aureochrome1-like protein, CHLORIDE ION, ... | | 著者 | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | 登録日 | 2018-10-31 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
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6I24
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | 1,2-ETHANEDIOL, 1-deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-5-O-phosphono-D-ribitol, ACETATE ION, ... | | 著者 | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | 登録日 | 2018-10-31 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
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6I20
 | | Flavin Analogue Sheds Light on Light-Oxygen-Voltage Domain Mechanism | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, ... | | 著者 | Rizkallah, P.J, Kalvaitis, M.E, Allemann, R.K, Mart, R.J, Johnson, L.A. | | 登録日 | 2018-10-31 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | A Noncanonical Chromophore Reveals Structural Rearrangements of the Light-Oxygen-Voltage Domain upon Photoactivation.
Biochemistry, 58, 2019
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3MY5
 | | CDk2/cyclinA in complex with DRB | | 分子名称: | 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole, Cell division protein kinase 2, Cyclin-A2, ... | | 著者 | Baumli, S, Johnson, L.N. | | 登録日 | 2010-05-09 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Halogen bonds form the basis for selective P-TEFb inhibition by DRB
Chem.Biol., 17, 2010
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1H0V
 | | Human cyclin dependent protein kinase 2 in complex with the inhibitor 2-Amino-6-[(R)-pyrrolidino-5'-yl]methoxypurine | | 分子名称: | 5-{[(2-AMINO-9H-PURIN-6-YL)OXY]METHYL}-2-PYRROLIDINONE, CELL DIVISION PROTEIN KINASE 2 | | 著者 | Gibson, A.E, Arris, C.E, Bentley, J, Boyle, F.T, Curtin, N.J, Davies, T.G, Endicott, J.A, Golding, B.T, Grant, S, Griffin, R.J, Jewsbury, P, Johnson, L.N, Mesguiche, V, Newell, D.R, Noble, M.E.M, Tucker, J.A, Whitfield, H.J. | | 登録日 | 2002-06-27 | | 公開日 | 2003-06-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O(6)-Substituted Guanine Derivatives
J.Med.Chem., 45, 2002
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1HCJ
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1H0W
 | | Human cyclin dependent protein kinase 2 in complex with the inhibitor 2-Amino-6-[cyclohex-3-enyl]methoxypurine | | 分子名称: | 1-AMINO-6-CYCLOHEX-3-ENYLMETHYLOXYPURINE, CELL DIVISION PROTEIN KINASE 2 | | 著者 | Gibson, A.E, Arris, C.E, Bentley, J, Boyle, F.T, Curtin, N.J, Davies, T.G, Endicott, J.A, Golding, B.T, Grant, S, Griffin, R.J, Jewsbury, P, Johnson, L.N, Mesguiche, V, Newell, D.R, Noble, M.E.M, Tucker, J.A, Whitfield, H.J. | | 登録日 | 2002-06-27 | | 公開日 | 2003-06-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O(6)-Substituted Guanine Derivatives
J.Med.Chem., 45, 2002
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3O3Z
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3O3X
 | | Crystal structure of gp41-5, a single-chain 5-helix-bundle based on HIV gp41 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ISOPROPYL ALCOHOL, gp41-5 | | 著者 | Horne, W.S, Johnson, L.M, Gellman, S.H. | | 登録日 | 2010-07-26 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Broad Distribution of Energetically Important Contacts across an Extended Protein Interface.
J.Am.Chem.Soc., 133, 2011
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3O3Y
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3HY2
 | | Crystal Structure of Sulfiredoxin in Complex with Peroxiredoxin I and ATP:Mg2+ | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Peroxiredoxin-1, ... | | 著者 | Jonsson, T.J, Johnson, L.C, Lowther, W.T. | | 登録日 | 2009-06-22 | | 公開日 | 2009-10-06 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Protein Engineering of the Quaternary Sulfiredoxin-Peroxiredoxin Enzyme-Substrate Complex Reveals the Molecular Basis for Cysteine Sulfinic Acid Phosphorylation
J.Biol.Chem., 284, 2009
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3O40
 | | Complex of a chimeric alpha/beta-peptide based on the gp41 CHR domain bound to gp41-5 | | 分子名称: | CHLORIDE ION, GLYCEROL, NONAETHYLENE GLYCOL, ... | | 著者 | Horne, W.S, Johnson, L.M, Gellman, S.H. | | 登録日 | 2010-07-26 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Broad Distribution of Energetically Important Contacts across an Extended Protein Interface.
J.Am.Chem.Soc., 133, 2011
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3O43
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3O42
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3MY1
 | | Structure of CDK9/cyclinT1 in complex with DRB | | 分子名称: | 5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole, Cell division protein kinase 9, Cyclin-T1, ... | | 著者 | Baumli, S, Johnson, L.N. | | 登録日 | 2010-05-09 | | 公開日 | 2010-09-29 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Halogen bonds form the basis for selective P-TEFb inhibition by DRB
Chem.Biol., 17, 2010
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1QIC
 | | CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN | | 分子名称: | CALCIUM ION, PROTEIN (STROMELYSIN-1), ZINC ION | | 著者 | Williams, M.G, Ye, Q.-Z, Molina, F, Johnson, L.L, Ortwine, D.F, Pavlovsky, A.G, Rubin, J.R, Skeean, R.W, White, A.D, Blundell, T.L, Humblet, C, Hupe, D.J, Dhanaraj, V. | | 登録日 | 1999-06-11 | | 公開日 | 2003-02-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity
Protein Sci., 8, 1999
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1QIA
 | | CRYSTAL STRUCTURE OF STROMELYSIN CATALYTIC DOMAIN | | 分子名称: | CALCIUM ION, STROMELYSIN-1, ZINC ION | | 著者 | Williams, M.G, Ye, Q.-Z, Molina, F, Johnson, L.L, Ortwine, D.F, Pavlovsky, A.G, Rubin, J.R, Skeean, R.W, White, A.D, Blundell, T.L, Humblet, C, Hupe, D.J, Dhanaraj, V. | | 登録日 | 1999-06-11 | | 公開日 | 2003-02-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity
Protein Sci., 8, 1999
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2GPB
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3CYI
 | | Crystal Structure of Human Sulfiredoxin (Srx) in Complex with ATP:Mg2+ | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Sulfiredoxin-1 | | 著者 | Jonsson, T.J, Murray, M.S, Johnson, L.C, Lowther, W.T. | | 登録日 | 2008-04-25 | | 公開日 | 2008-07-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Reduction of Cysteine Sulfinic Acid in Peroxiredoxin by Sulfiredoxin Proceeds Directly through a Sulfinic Phosphoryl Ester Intermediate.
J.Biol.Chem., 283, 2008
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1QIB
 | | CRYSTAL STRUCTURE OF GELATINASE A CATALYTIC DOMAIN | | 分子名称: | 72 kDa type IV collagenase, CALCIUM ION, ZINC ION | | 著者 | Dhanaraj, V, Williams, M.G, Ye, Q.-Z, Molina, F, Johnson, L.L, Ortwine, D.F, Pavlovsky, A, Rubin, J.R, Skeean, R.W, White, A.D, Humblet, C, Hupe, D.J, Blundell, T.L. | | 登録日 | 1999-06-11 | | 公開日 | 1999-11-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | X-ray structure of gelatinase A catalytic domain complexed with a hydroxamate inhibitor
Croatica Chemica Acta, 72, 1999
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3G7A
 | | HIV gp41 six-helix bundle composed of a chimeric alpha+alpha/beta-peptide analogue of the CHR domain in complex with an NHR domain alpha-peptide | | 分子名称: | ACETYL GROUP, Chimeric alpha+alpha/beta-peptide analogue of the HIV gp41 CHR domain, Envelope glycoprotein gp160, ... | | 著者 | Horne, W.S, Johnson, L.M, Gellman, S.H. | | 登録日 | 2009-02-09 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural and biological mimicry of protein surface recognition by alpha/beta-peptide foldamers
Proc.Natl.Acad.Sci.USA, 106, 2009
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1ABB
 | | CONTROL OF PHOSPHORYLASE B CONFORMATION BY A MODIFIED COFACTOR: CRYSTALLOGRAPHIC STUDIES ON R-STATE GLYCOGEN PHOSPHORYLASE RECONSTITUTED WITH PYRIDOXAL 5'-DIPHOSPHATE | | 分子名称: | GLYCOGEN PHOSPHORYLASE B, INOSINIC ACID, PYRIDOXAL-5'-DIPHOSPHATE, ... | | 著者 | Leonidas, D.D, Oikonomakos, N.G, Papageorgiou, A.C, Acharya, K.R, Barford, D, Johnson, L.N. | | 登録日 | 1992-04-09 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate.
Protein Sci., 1, 1992
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1C50
 | | IDENTIFICATION AND STRUCTURAL CHARACTERIZATION OF A NOVEL ALLOSTERIC BINDING SITE OF GLYCOGEN PHOSPHORYLASE B | | 分子名称: | 5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID [1-(4-FLUOROBENZYL)-2-(4-HYDROXYPIPERIDIN-1YL)-2-OXOETHYL]AMIDE, PROTEIN (GLYCOGEN PHOSPHORYLASE), PYRIDOXAL-5'-PHOSPHATE | | 著者 | Oikonomakos, N.G, Skamnaki, V.T, Tsitsanou, K.E, Gavalas, N.G, Johnson, L.N. | | 登録日 | 1999-12-15 | | 公開日 | 1999-12-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A new allosteric site in glycogen phosphorylase b as a target for drug interactions.
Structure Fold.Des., 8, 2000
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