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PDB: 80 results
6Z7X
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BU of 6z7x by Molmil
Insulin analytical antibody OXI-005 Fab
Descriptor: OXI-005 Fab Heavy chain, OXI-005 Fab Light chain
Authors:Johansson, E.
Deposit date:2020-06-02
Release date:2020-12-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties.
Protein Sci., 30, 2021
1OGH
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BU of 1ogh by Molmil
Structure of the bifunctional dCTP deaminase-dUTPase from Methanocaldococcus jannaschii
Descriptor: BIFUNCTIONAL DEAMINASE/DIPHOSPHATASE
Authors:Johansson, E, Bjornberg, O, Nyman, P.O, Larsen, S.
Deposit date:2003-05-02
Release date:2003-06-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structure of the Bifunctional Dctp Deaminase-Dutpase from Methanocaldococcus Jannaschii and its Relation to Other Homotrimeric Dutpases
J.Biol.Chem., 278, 2003
6S4J
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BU of 6s4j by Molmil
Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB27, desB30 human insulin
Descriptor: IMIDAZOLE, Insulin, KUT [2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]
Authors:Johansson, E.
Deposit date:2019-06-28
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular engineering of safe and efficacious oral basal insulin.
Nat Commun, 11, 2020
6S4I
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BU of 6s4i by Molmil
Crystal structure of zinc free A14E, B25H, B29K(N(eps)-[2-(2-[2-(2-[2-(Octadecandioyl-gamma-Glu)amino]ethoxy)ethoxy]acetylamino)ethoxy]ethoxy)acetyl]), desB30 human insulin
Descriptor: Insulin, NITRATE ION
Authors:Johansson, E.
Deposit date:2019-06-28
Release date:2020-07-15
Last modified:2020-08-12
Method:X-RAY DIFFRACTION (1.511 Å)
Cite:Molecular engineering of safe and efficacious oral basal insulin.
Nat Commun, 11, 2020
1XS4
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BU of 1xs4 by Molmil
dCTP deaminase from Escherichia coli- E138A mutant enzyme in complex with dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION
Authors:Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M.
Deposit date:2004-10-18
Release date:2004-12-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes
J.Biol.Chem., 280, 2005
1XS1
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BU of 1xs1 by Molmil
dCTP deaminase from Escherichia coli in complex with dUTP
Descriptor: DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION
Authors:Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M.
Deposit date:2004-10-18
Release date:2004-12-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes
J.Biol.Chem., 280, 2005
1XS6
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BU of 1xs6 by Molmil
dCTP deaminase from Escherichia coli. E138A mutant enzyme in complex with dUTP
Descriptor: DEOXYURIDINE-5'-TRIPHOSPHATE, Deoxycytidine triphosphate deaminase, MAGNESIUM ION
Authors:Johansson, E, Fano, M, Bynck, J.H, Neuhard, J, Larsen, S, Sigurskjold, B.W, Christensen, U, Willemoes, M.
Deposit date:2004-10-18
Release date:2004-12-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes
J.Biol.Chem., 280, 2005
1UX0
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BU of 1ux0 by Molmil
Bacillus subtilis cytidine deaminase with an Arg56 - Gln substitution
Descriptor: CYTIDINE DEAMINASE, TETRAHYDRODEOXYURIDINE, ZINC ION
Authors:Johansson, E, Neuhard, J, Willemoes, M, Larsen, S.
Deposit date:2004-02-18
Release date:2004-05-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase
Biochemistry, 43, 2004
6QIP
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BU of 6qip by Molmil
Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the albumin-biniding side chain of the human growth hormone derivative somapacitan
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-MERCAPTOETHANOL, Beta-2-microglobulin, ...
Authors:Johansson, E.
Deposit date:2019-01-21
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Identification of Binding Sites on Human Serum Albumin for Somapacitan, a Long-Acting Growth Hormone Derivative.
Biochemistry, 59, 2020
6QIO
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BU of 6qio by Molmil
Ternary complex of FcRn ectodomain, FcRn binding optimised human serum albumin and the human growth hormone derivative somapacitan
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, CYSTEINE, ...
Authors:Johansson, E.
Deposit date:2019-01-21
Release date:2020-02-05
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Identification of Binding Sites on Human Serum Albumin for Somapacitan, a Long-Acting Growth Hormone Derivative.
Biochemistry, 59, 2020
1UX1
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BU of 1ux1 by Molmil
Bacillus subtilis cytidine deaminase with a Cys53His and an Arg56Gln substitution
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CYTIDINE DEAMINASE, TETRAHYDRODEOXYURIDINE, ...
Authors:Johansson, E, Neuhard, J, Willemoes, M, Larsen, S.
Deposit date:2004-02-18
Release date:2004-05-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase
Biochemistry, 43, 2004
1UWZ
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BU of 1uwz by Molmil
Bacillus subtilis cytidine deaminase with an Arg56 - Ala substitution
Descriptor: CYTIDINE DEAMINASE, TETRAHYDRODEOXYURIDINE, ZINC ION
Authors:Johansson, E, Neuhard, J, Willemoes, M, Larsen, S.
Deposit date:2004-02-18
Release date:2004-05-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural, Kinetic, and Mutational Studies of the Zinc Ion Environment in Tetrameric Cytidine Deaminase
Biochemistry, 43, 2004
3DCQ
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BU of 3dcq by Molmil
LECB (PA-LII) in complex with the synthetic ligand 2G0
Descriptor: (2S)-1-[(2S)-6-amino-2-({[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]acetyl}amino)hexanoyl]-N-[(1S)-1-carbamoyl-3-methylbutyl]pyrrolidine-2-carboxamide, CALCIUM ION, Fucose-binding lectin PA-IIL
Authors:Johansson, E.M, Crusz, S.A, Kolomiets, E, Buts, L, Kadam, R.U, Cacciarini, M, Bartels, K.M, Diggle, S.P, Camara, M, Williams, P, Loris, R, Nativi, C, Rosenau, F, Jaeger, K.E, Darbre, T, Reymond, J.L.
Deposit date:2008-06-04
Release date:2009-01-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB.
Chem.Biol., 15, 2008
2J4H
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BU of 2j4h by Molmil
Crystal structure of a H121A Escherichia coli dCTP deaminase mutant enzyme
Descriptor: DEOXYCYTIDINE DIPHOSPHATE, DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION
Authors:Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M.
Deposit date:2006-08-31
Release date:2007-08-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme
FEBS J., 274, 2007
2J4Q
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BU of 2j4q by Molmil
Crystal structure of a E138A Escherichia coli dCTP deaminase mutant enzyme in complex with dTTP
Descriptor: DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Johansson, E, Thymark, M, Bynck, J.H, Fanoe, M, Larsen, S, Willemoes, M.
Deposit date:2006-09-05
Release date:2007-08-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulation of Dctp Deaminase from Escherichia Coli by Nonallosteric Dttp Binding to an Inactive Form of the Enzyme
FEBS J., 274, 2007
5II0
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BU of 5ii0 by Molmil
Crystal structure of the human calcitonin receptor ectodomain in complex with a truncated salmon calcitonin analogue
Descriptor: Calcitonin, Calcitonin receptor, SODIUM ION, ...
Authors:Johansson, E, Reedtz-Runge, S.
Deposit date:2016-03-01
Release date:2016-05-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Type II Turn of Receptor-bound Salmon Calcitonin Revealed by X-ray Crystallography.
J.Biol.Chem., 291, 2016
5J4S
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BU of 5j4s by Molmil
alpha-chymotrypsin from bovine pancreas in complex with a modified Bowman-Birk inhibitor from soybean
Descriptor: Bowman-Birk type proteinase inhibitor, Chymotrypsinogen A
Authors:Johansson, E, Tornoee, C.W.
Deposit date:2016-04-01
Release date:2017-04-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Divergent Protein Synthesis of Bowman-Birk Protease Inhibitors, their Hydrodynamic Behavior and Co-crystallization with alpha-Chymotrypsin
Synlett, 2017
5J4Q
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BU of 5j4q by Molmil
alpha-chymotrypsin from bovine pancreas in complex with Bowman-Birk inhibitor from soybean
Descriptor: Bowman-Birk type proteinase inhibitor, Chymotrypsinogen A
Authors:Johansson, E, Tornoee, C.W.
Deposit date:2016-04-01
Release date:2017-04-12
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Divergent Protein Synthesis of Bowman-Birk Protease Inhibitors, their Hydrodynamic Behavior and Co-crystallization with alpha-Chymotrypsin
Synlett, 2017
4M8O
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BU of 4m8o by Molmil
TERNARY COMPLEX OF DNA POLYMERASE EPSILON WITH AN INCOMING dATP
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2-AMINOETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Sauer-Eriksson, A.E, Hogg, M, Osterman, P, Johansson, E.
Deposit date:2013-08-13
Release date:2013-11-27
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for processive DNA synthesis by yeast DNA polymerase epsilon.
Nat.Struct.Mol.Biol., 21, 2014
8B67
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BU of 8b67 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing CTP in the polymerase active site
Descriptor: ACETATE ION, CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-26
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B79
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BU of 8b79 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing UTP in the polymerase active site
Descriptor: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-29
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B7E
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BU of 8b7e by Molmil
The crystal structure of N828V variant of DNA Pol Epsilon containing UTP in the polymerase active site
Descriptor: CALCIUM ION, DNA polymerase epsilon catalytic subunit A, GLYCEROL, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-29
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B6K
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BU of 8b6k by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing dCTP in the polymerase active site
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-27
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B77
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BU of 8b77 by Molmil
The crystal structure of N828V variant of DNA Pol Epsilon containing dATP in the polymerase active site
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-29
Release date:2023-10-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B76
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BU of 8b76 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing dTTP in the polymerase active site
Descriptor: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
Authors:Parkash, V, Johansson, E.
Deposit date:2022-09-28
Release date:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023

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