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PDB: 134 results
2WQJ
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BU of 2wqj by Molmil
Crystal structure of a truncated variant of the human p73 tetramerization domain
Descriptor: TUMOR PROTEIN P73
Authors:Joerger, A.C.
Deposit date:2009-08-21
Release date:2009-10-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WQI
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BU of 2wqi by Molmil
Crystal structure of the human p73 tetramerization domain
Descriptor: TUMOR PROTEIN P73
Authors:Joerger, A.C.
Deposit date:2009-08-21
Release date:2009-10-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WTT
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BU of 2wtt by Molmil
Structure of the human p73 tetramerization domain (crystal form II)
Descriptor: TUMOR PROTEIN P73
Authors:Joerger, A.C.
Deposit date:2009-09-21
Release date:2009-10-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Evolution of P53, P63, and P73: Implication for Heterotetramer Formation.
Proc.Natl.Acad.Sci.USA, 106, 2009
2XWR
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BU of 2xwr by Molmil
Crystal structure of the DNA-binding domain of human p53 with extended N terminus
Descriptor: CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C, Natan, E, Fersht, A.R.
Deposit date:2010-11-04
Release date:2011-03-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Interaction of the P53 DNA-Binding Domain with its N-Terminal Extension Modulates the Stability of the P53 Tetramer.
J.Mol.Biol., 409, 2011
6GGD
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BU of 6ggd by Molmil
p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9324
Descriptor: Cellular tumor antigen p53, GLYCEROL, ZINC ION, ...
Authors:Joerger, A.C, Bauer, M.R.
Deposit date:2018-05-03
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.40000892 Å)
Cite:A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.
Future Med Chem, 11, 2019
6GGB
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BU of 6ggb by Molmil
p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9318
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cellular tumor antigen p53, ...
Authors:Joerger, A.C, Bauer, M.R.
Deposit date:2018-05-03
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.
Future Med Chem, 11, 2019
6GGA
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BU of 6gga by Molmil
p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9284
Descriptor: (7-bromanyl-9-ethyl-carbazol-3-yl)methyl-methyl-azanium, Cellular tumor antigen p53, ZINC ION
Authors:Joerger, A.C, Bauer, M.R.
Deposit date:2018-05-03
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.55000126 Å)
Cite:A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.
Future Med Chem, 11, 2019
6GGE
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BU of 6gge by Molmil
p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9327
Descriptor: Cellular tumor antigen p53, ZINC ION, [9-ethyl-7-(5-methylthiophen-2-yl)carbazol-3-yl]methyl-methyl-azanium
Authors:Joerger, A.C, Bauer, M.R.
Deposit date:2018-05-03
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.25000513 Å)
Cite:A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.
Future Med Chem, 11, 2019
6GGC
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BU of 6ggc by Molmil
p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9320
Descriptor: 1,2-ETHANEDIOL, Cellular tumor antigen p53, GLYCEROL, ...
Authors:Joerger, A.C.
Deposit date:2018-05-03
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.
Future Med Chem, 11, 2019
6GGF
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BU of 6ggf by Molmil
Structure of the p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9328
Descriptor: Cellular tumor antigen p53, GLYCEROL, ZINC ION, ...
Authors:Joerger, A.C, Bauer, M.R.
Deposit date:2018-05-03
Release date:2019-05-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.32000017 Å)
Cite:A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.
Future Med Chem, 11, 2019
4CZ5
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BU of 4cz5 by Molmil
Truncated tetramerization domain of zebrafish p53 (crystal form I)
Descriptor: CELLULAR TUMOR ANTIGEN P53
Authors:Joerger, A.C.
Deposit date:2014-04-16
Release date:2014-08-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.02 Å)
Cite:Tracing the Evolution of the P53 Tetramerization Domain
Structure, 22, 2014
4CZ7
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BU of 4cz7 by Molmil
Truncated tetramerization domain of zebrafish p53 (crystal form III)
Descriptor: CELLULAR TUMOR ANTIGEN P53, GLYCEROL, PHOSPHATE ION
Authors:Joerger, A.C.
Deposit date:2014-04-16
Release date:2014-08-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Tracing the Evolution of the P53 Tetramerization Domain
Structure, 22, 2014
4CZ6
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BU of 4cz6 by Molmil
Truncated tetramerization domain of zebrafish p53 (crystal form II)
Descriptor: CELLULAR TUMOR ANTIGEN P53, DI(HYDROXYETHYL)ETHER
Authors:Joerger, A.C.
Deposit date:2014-04-16
Release date:2014-08-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Tracing the Evolution of the P53 Tetramerization Domain
Structure, 22, 2014
4D1L
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BU of 4d1l by Molmil
Tetramerization domain of zebrafish p53 (crystal form I)
Descriptor: CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C.
Deposit date:2014-05-02
Release date:2014-08-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Tracing the Evolution of the P53 Tetramerization Domain
Structure, 22, 2014
4D1M
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BU of 4d1m by Molmil
Tetramerization domain of zebrafish p53 (crystal form II)
Descriptor: CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C.
Deposit date:2014-05-02
Release date:2014-08-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Tracing the Evolution of the P53 Tetramerization Domain
Structure, 22, 2014
1E46
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BU of 1e46 by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant E73S
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1E4B
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BU of 1e4b by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant N29Q
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1E48
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BU of 1e48 by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant E73Q/Y113F/Y209F
Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1E47
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BU of 1e47 by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant E73Q
Descriptor: 1,3-DIHYDROXYACETONEPHOSPHATE, BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of l-fuculose-1-phosphate aldolase mutants outlining motions during catalysis.
J. Mol. Biol., 303, 2000
1E4C
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BU of 1e4c by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant S71Q
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1E49
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BU of 1e49 by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant N29L/S71A
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1E4A
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BU of 1e4a by Molmil
L-Fuculose 1-Phosphate Aldolase from Escherichia coli Mutant Del(27)
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE 1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-06-30
Release date:2000-11-06
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of L-Fuculose-1-Phosphate Aldolase Mutants Outlining Motions During Catalysis
J.Mol.Biol., 303, 2000
1DZY
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BU of 1dzy by Molmil
L-Fuculose-1-Phosphate Aldolase from Escherichia coli Mutant E214A
Descriptor: BETA-MERCAPTOETHANOL, L-FUCULOSE-1-PHOSPHATE ALDOLASE, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-03-07
Release date:2000-06-02
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Catalytic Action of Fuculose 1-Phosphate Aldolase (Class II) as Derived from Structure-Directed Mutagenesis
Biochemistry, 39, 2000
1DZZ
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BU of 1dzz by Molmil
L-Fuculose-1-Phosphate Aldolase from Escherichia coli Mutant Y113F
Descriptor: BETA-MERCAPTOETHANOL, L-fuculose phosphate aldolase, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-03-07
Release date:2000-06-02
Last modified:2019-09-25
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Catalytic Action of Fuculose 1-Phosphate Aldolase (Class II) as Derived from Structure-Directed Mutagenesis
Biochemistry, 39, 2000
1DZV
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BU of 1dzv by Molmil
L-Fuculose-1-Phosphate Aldolase from Escherichia coli Mutant Y113F/Y209F
Descriptor: BETA-MERCAPTOETHANOL, L-fuculose phosphate aldolase, SULFATE ION, ...
Authors:Joerger, A.C, Schulz, G.E.
Deposit date:2000-03-07
Release date:2000-06-02
Last modified:2019-09-25
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Catalytic Action of Fuculose 1-Phosphate Aldolase (Class II) as Derived from Structure-Directed Mutagenesis
Biochemistry, 39, 2000

224572

數據於2024-09-04公開中

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