7T5F
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3H5V
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![BU of 3h5v by Molmil](/molmil-images/mine/3h5v) | Crystal structure of the GluR2-ATD | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 2 | Authors: | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | Deposit date: | 2009-04-22 | Release date: | 2009-06-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | Crystal structure and association behaviour of the GluR2 amino-terminal domain. Embo J., 28, 2009
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3H5W
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![BU of 3h5w by Molmil](/molmil-images/mine/3h5w) | Crystal structure of the GluR2-ATD in space group P212121 without solvent | Descriptor: | Glutamate receptor 2 | Authors: | Jin, R, Singh, S.K, Gu, S, Furukawa, H, Sobolevsky, A, Zhou, J, Jin, Y, Gouaux, E. | Deposit date: | 2009-04-22 | Release date: | 2009-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.686 Å) | Cite: | Crystal structure and association behaviour of the GluR2 amino-terminal domain. Embo J., 28, 2009
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7UIE
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![BU of 7uie by Molmil](/molmil-images/mine/7uie) | Crystal structure of HcE-JLE-G6 | Descriptor: | Botulinum neurotoxin E heavy chain, JLE-G6 | Authors: | Jin, R, Lam, K. | Deposit date: | 2022-03-29 | Release date: | 2023-04-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2. Nat Commun, 14, 2023
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3SAJ
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![BU of 3saj by Molmil](/molmil-images/mine/3saj) | Crystal Structure of glutamate receptor GluA1 Amino Terminal Domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 1, ... | Authors: | Jin, R, Zong, Y, Yao, G, Gu, S. | Deposit date: | 2011-06-02 | Release date: | 2011-06-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the glutamate receptor GluA1 N-terminal domain. Biochem.J., 438, 2011
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5VMR
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![BU of 5vmr by Molmil](/molmil-images/mine/5vmr) | |
5VID
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1MXU
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![BU of 1mxu by Molmil](/molmil-images/mine/1mxu) | CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) in complex with bromo-willardiine (Control for the crystal titration experiments) | Descriptor: | 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
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1MXV
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![BU of 1mxv by Molmil](/molmil-images/mine/1mxv) | crystal titration experiments (AMPA co-crystals soaked in 10 mM BrW) | Descriptor: | GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
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1MY2
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![BU of 1my2 by Molmil](/molmil-images/mine/1my2) | crystal titration experiment (AMPA complex control) | Descriptor: | (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry, 42, 2003
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1MXY
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![BU of 1mxy by Molmil](/molmil-images/mine/1mxy) | crystal titration experiments (AMPA co-crystals soaked in 10 uM BrW) | Descriptor: | GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry, 42, 2003
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1MXW
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![BU of 1mxw by Molmil](/molmil-images/mine/1mxw) | crystal titration experiments (AMPA co-crystals soaked in 1 mM BrW) | Descriptor: | GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry, 42, 2003
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1MY4
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![BU of 1my4 by Molmil](/molmil-images/mine/1my4) | crystal structure of glutamate receptor ligand-binding core in complex with iodo-willardiine in the Zn crystal form | Descriptor: | 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
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1MXZ
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![BU of 1mxz by Molmil](/molmil-images/mine/1mxz) | crystal titration experiments (AMPA co-crystals soaked in 1 uM BrW) | Descriptor: | GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. Biochemistry, 42, 2003
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1MXX
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![BU of 1mxx by Molmil](/molmil-images/mine/1mxx) | crystal titration experiments (AMPA co-crystals soaked in 100 uM BrW) | Descriptor: | GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
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1MY3
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![BU of 1my3 by Molmil](/molmil-images/mine/1my3) | crystal structure of glutamate receptor ligand-binding core in complex with bromo-willardiine in the Zn crystal form | Descriptor: | 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core:
Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
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1MY0
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![BU of 1my0 by Molmil](/molmil-images/mine/1my0) | crystal titration experiments (AMPA co-crystals soaked in 100 nM BrW) | Descriptor: | GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
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1MY1
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![BU of 1my1 by Molmil](/molmil-images/mine/1my1) | crystal titration experiments (AMPA co-crystals soaked in 10 nM BrW) | Descriptor: | GLUTAMATE RECEPTOR 2, ZINC ION | Authors: | Jin, R, Gouaux, E. | Deposit date: | 2002-10-03 | Release date: | 2003-06-10 | Last modified: | 2017-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the Function, Conformational Plasticity, and Dimer-Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal Biochemistry, 42, 2003
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2AL4
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![BU of 2al4 by Molmil](/molmil-images/mine/2al4) | CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH quisqualate and CX614. | Descriptor: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE, Glutamate receptor 2, ... | Authors: | Jin, R, Clark, S, Weeks, A.M, Dudman, J.T, Gouaux, E, Partin, K.M. | Deposit date: | 2005-08-04 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of positive allosteric modulators acting on AMPA receptors. J.Neurosci., 25, 2005
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2AL5
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![BU of 2al5 by Molmil](/molmil-images/mine/2al5) | Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with fluoro-willardiine and aniracetam | Descriptor: | 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2 | Authors: | Jin, R, Clark, S, Weeks, A.M, Dudman, J.T, Gouaux, E, Partin, K.M. | Deposit date: | 2005-08-04 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Mechanism of positive allosteric modulators acting on AMPA receptors. J.Neurosci., 25, 2005
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1ZC4
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![BU of 1zc4 by Molmil](/molmil-images/mine/1zc4) | Crystal structure of the Ral-binding domain of Exo84 in complex with the active RalA | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Ral-A, ... | Authors: | Jin, R, Junutula, J.R, Matern, H.T, Ervin, K.E, Scheller, R.H, Brunger, A.T. | Deposit date: | 2005-04-10 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase. Embo J., 24, 2005
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1ZC3
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![BU of 1zc3 by Molmil](/molmil-images/mine/1zc3) | Crystal structure of the Ral-binding domain of Exo84 in complex with the active RalA | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein Ral-A, ... | Authors: | Jin, R, Junutula, J.R, Matern, H.T, Ervin, K.E, Scheller, R.H, Brunger, A.T. | Deposit date: | 2005-04-10 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase. Embo J., 24, 2005
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1MQH
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![BU of 1mqh by Molmil](/molmil-images/mine/1mqh) | Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Bromo-Willardiine at 1.8 Angstroms Resolution | Descriptor: | 2-AMINO-3-(5-BROMO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, glutamate receptor 2 | Authors: | Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E. | Deposit date: | 2002-09-16 | Release date: | 2003-08-05 | Last modified: | 2017-08-02 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for partial agonist action at ionotropic glutamate receptors Nat.Neurosci., 6, 2003
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1MQI
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![BU of 1mqi by Molmil](/molmil-images/mine/1mqi) | Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Fluoro-Willardiine at 1.35 Angstroms Resolution | Descriptor: | 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, glutamate receptor 2 | Authors: | Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E. | Deposit date: | 2002-09-16 | Release date: | 2003-08-05 | Last modified: | 2017-08-02 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structural basis for partial agonist action at ionotropic glutamate receptors Nat.Neurosci., 6, 2003
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1MQJ
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![BU of 1mqj by Molmil](/molmil-images/mine/1mqj) | Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution | Descriptor: | 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ZINC ION, glutamate receptor 2 | Authors: | Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E. | Deposit date: | 2002-09-16 | Release date: | 2003-08-05 | Last modified: | 2017-08-02 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for partial agonist action at ionotropic glutamate receptors Nat.Neurosci., 6, 2003
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